ZIDAPAMIDE

Details

Stereochemistry	RACEMIC
Molecular Formula	C16H16ClN3O3S
Molecular Weight	365.835
Optical Activity	( + / - )
Defined Stereocenters	0 / 1
E/Z Centers	0
Charge	0

SHOW SMILES / InChI

Structure Search

SMILES

CC1N(CC2=C1C=CC=C2)NC(=O)C3=CC=C(Cl)C(=C3)S(N)(=O)=O

InChI

InChIKey=BHUKYXOYJMLRAK-UHFFFAOYSA-N

InChI=1S/C16H16ClN3O3S/c1-10-13-5-3-2-4-12(13)9-20(10)19-16(21)11-6-7-14(17)15(8-11)24(18,22)23/h2-8,10H,9H2,1H3,(H,19,21)(H2,18,22,23)

HIDE SMILES / InChI

Molecular Formula	C16H16ClN3O3S
Molecular Weight	365.835
Charge	0
Count

Stereochemistry	RACEMIC
Additional Stereochemistry	No
Defined Stereocenters	0 / 1
E/Z Centers	0
Optical Activity	( + / - )

Description
Sources: https://www.google.com/patents/US4338331 | https://ncit.nci.nih.gov/ncitbrowser/ConceptReport.jsp?dictionary=NCI_Thesaurus&ns=NCI_Thesaurus&code=C82267 | https://books.google.com/books?id=_J2ti4EkYpkC&printsec=frontcover&hl=ru#v=onepage&q&f=false

Zidapamide (1-methyl-2-(3'-sulphenyl-4'-chlorobenzamido)-isoindoline) is an isoindoline derivative exerting diuretic, salutaric and hypotensive activity.

Originator

Approval Year

Conditions

Condition	Modality	Targets	Highest Phase	Product
Hypertension 575 Sources: https://www.google.com/patents/US4338331	Primary		Preclinical	Unknown Approved Use Unknown

Patents

Sample Use Guides

In Vivo Use Guide

In rodents zidapamide can be administered orally in a dose of 2.5-5 mg per day, depending upon whether it is required to utilize its hypertensive or diuretic action.

Route of Administration: Oral

In Vitro Use Guide

Unknown

Substance Class	Chemical Created by `admin` on `Wed Apr 02 09:30:23 GMT 2025` Edited by `admin` on `Wed Apr 02 09:30:23 GMT 2025`
Record UNII	F7KU1MIY58
Record Status	`Validated (UNII)`
Record Version

Download

Name

Type

Language

ISODAPAMIDE

Preferred Name

English

ZIDAPAMIDE

Official Name

English

4-CHLORO-N-(1-METHYL-2-ISOINDOLINYL)-3-SULFAMOYLBENZAMIDE

Systematic Name

English

zidapamide [INN]

Common Name

English

ZIDAPAMIDE [USAN]

Common Name

English

Classification Tree Code System Code

NCI_THESAURUS

C448