ABANOQUIL

U.S. Department of Health & Human Services Divider Arrow

National Institutes of Health Divider Arrow

NCATS

Details

Stereochemistry	ACHIRAL
Molecular Formula	C22H25N3O4
Molecular Weight	395.4516
Optical Activity	NONE
Defined Stereocenters	0 / 0
E/Z Centers	0
Charge	0

SHOW SMILES / InChI

Structure of ABANOQUIL

Structure Search

SMILES

COC1=CC2=C(CN(CC2)C3=NC4=CC(OC)=C(OC)C=C4C(N)=C3)C=C1OC

InChI

InChIKey=ANZIISNSHPKVRV-UHFFFAOYSA-N

InChI=1S/C22H25N3O4/c1-26-18-7-13-5-6-25(12-14(13)8-19(18)27-2)22-10-16(23)15-9-20(28-3)21(29-4)11-17(15)24-22/h7-11H,5-6,12H2,1-4H3,(H2,23,24)

HIDE SMILES / InChI

Molecular Formula	C22H25N3O4
Molecular Weight	395.4516
Charge	0
Count

Stereochemistry	ACHIRAL
Additional Stereochemistry	No
Defined Stereocenters	0 / 0
E/Z Centers	0
Optical Activity	NONE

Description
Sources: https://www.ncbi.nlm.nih.gov/pubmed/10845763

Abanoquil (UK-52,046), an antiarrhythmic drug, is an alpha 1-adrenoceptor antagonist, has been studied for the treatment of erectile dysfunction.

Approval Year

Targets

Targets

Primary Target	Pharmacology	Condition	Potency
Adrenergic receptor alpha-1 169 Target ID: CHEMBL2094251 Sources: https://www.ncbi.nlm.nih.gov/pubmed/10845763	Antagonist 2778

PubMed

PubMed

Title	Date	PubMed

Patents

Patents

Sample Use Guides

In Vivo Use Guide

single oral doses of abanoquil 0.25, 0.5 and 1 mg

Route of Administration: Oral

Substance Class	Chemical Created by `admin` on `Sat Dec 16 17:50:36 UTC 2023` Edited by `admin` on `Sat Dec 16 17:50:36 UTC 2023`
Record UNII	F738MWY53L
Record Status	`Validated (UNII)`
Record Version

Download

Name

Type

Language

ABANOQUIL

Official Name

English

4-AMINO-2-(3,4-DIHYDRO-6,7-DIMETHOXY-2(1H)-ISOQUINOLYL)-6,7-DIMETHOXYQUINOLINE

Systematic Name

English

abanoquil [INN]

Common Name

English

Classification Tree Code System Code

NCI_THESAURUS

C29713

Created by admin on Sat Dec 16 17:50:36 UTC 2023 , Edited by admin on Sat Dec 16 17:50:36 UTC 2023

Code System Code Type Description

WIKIPEDIA

ABANOQUIL

Created by admin on Sat Dec 16 17:50:36 UTC 2023 , Edited by admin on Sat Dec 16 17:50:36 UTC 2023

PRIMARY

FDA UNII

F738MWY53L

Created by admin on Sat Dec 16 17:50:36 UTC 2023 , Edited by admin on Sat Dec 16 17:50:36 UTC 2023

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INN

6761

Created by admin on Sat Dec 16 17:50:36 UTC 2023 , Edited by admin on Sat Dec 16 17:50:36 UTC 2023

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NCI_THESAURUS

C72566

Created by admin on Sat Dec 16 17:50:36 UTC 2023 , Edited by admin on Sat Dec 16 17:50:36 UTC 2023

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MESH

C058534

Created by admin on Sat Dec 16 17:50:36 UTC 2023 , Edited by admin on Sat Dec 16 17:50:36 UTC 2023

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SMS_ID

100000082323

Created by admin on Sat Dec 16 17:50:36 UTC 2023 , Edited by admin on Sat Dec 16 17:50:36 UTC 2023

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PUBCHEM

164089

Created by admin on Sat Dec 16 17:50:36 UTC 2023 , Edited by admin on Sat Dec 16 17:50:36 UTC 2023

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ChEMBL

CHEMBL324090

Created by admin on Sat Dec 16 17:50:36 UTC 2023 , Edited by admin on Sat Dec 16 17:50:36 UTC 2023

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EPA CompTox

DTXSID40238163

Created by admin on Sat Dec 16 17:50:36 UTC 2023 , Edited by admin on Sat Dec 16 17:50:36 UTC 2023

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CAS

90402-40-7

Created by admin on Sat Dec 16 17:50:36 UTC 2023 , Edited by admin on Sat Dec 16 17:50:36 UTC 2023

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EVMPD

SUB07358MIG

Created by admin on Sat Dec 16 17:50:36 UTC 2023 , Edited by admin on Sat Dec 16 17:50:36 UTC 2023

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Related Record Type Details


					F738MWY53L

ABANOQUIL

ACTIVE MOIETY