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Details

Stereochemistry ACHIRAL
Molecular Formula C22H25N3O4
Molecular Weight 395.4516
Optical Activity NONE
Defined Stereocenters 0 / 0
E/Z Centers 0
Charge 0

SHOW SMILES / InChI
Structure of ABANOQUIL

SMILES

COC1=CC2=C(CN(CC2)C3=NC4=CC(OC)=C(OC)C=C4C(N)=C3)C=C1OC

InChI

InChIKey=ANZIISNSHPKVRV-UHFFFAOYSA-N
InChI=1S/C22H25N3O4/c1-26-18-7-13-5-6-25(12-14(13)8-19(18)27-2)22-10-16(23)15-9-20(28-3)21(29-4)11-17(15)24-22/h7-11H,5-6,12H2,1-4H3,(H2,23,24)

HIDE SMILES / InChI

Molecular Formula C22H25N3O4
Molecular Weight 395.4516
Charge 0
Count
Stereochemistry ACHIRAL
Additional Stereochemistry No
Defined Stereocenters 0 / 0
E/Z Centers 0
Optical Activity NONE

Abanoquil (UK-52,046), an antiarrhythmic drug, is an alpha 1-adrenoceptor antagonist, has been studied for the treatment of erectile dysfunction.

Approval Year

Targets

Targets

Primary TargetPharmacologyConditionPotency
PubMed

PubMed

TitleDatePubMed
Abanoquil, a new alpha-1 adrenoceptor antagonist. In vitro and in vivo effect on erectile tissue.
2000 Mar
Patents

Patents

Sample Use Guides

single oral doses of abanoquil 0.25, 0.5 and 1 mg
Route of Administration: Oral
Substance Class Chemical
Created
by admin
on Thu Jul 06 23:10:27 UTC 2023
Edited
by admin
on Thu Jul 06 23:10:27 UTC 2023
Record UNII
F738MWY53L
Record Status Validated (UNII)
Record Version
  • Download
Name Type Language
ABANOQUIL
INN  
INN  
Official Name English
4-AMINO-2-(3,4-DIHYDRO-6,7-DIMETHOXY-2(1H)-ISOQUINOLYL)-6,7-DIMETHOXYQUINOLINE
Systematic Name English
abanoquil [INN]
Common Name English
Classification Tree Code System Code
NCI_THESAURUS C29713
Created by admin on Thu Jul 06 23:10:27 UTC 2023 , Edited by admin on Thu Jul 06 23:10:27 UTC 2023
Code System Code Type Description
WIKIPEDIA
ABANOQUIL
Created by admin on Thu Jul 06 23:10:27 UTC 2023 , Edited by admin on Thu Jul 06 23:10:27 UTC 2023
PRIMARY
FDA UNII
F738MWY53L
Created by admin on Thu Jul 06 23:10:27 UTC 2023 , Edited by admin on Thu Jul 06 23:10:27 UTC 2023
PRIMARY
INN
6761
Created by admin on Thu Jul 06 23:10:27 UTC 2023 , Edited by admin on Thu Jul 06 23:10:27 UTC 2023
PRIMARY
NCI_THESAURUS
C72566
Created by admin on Thu Jul 06 23:10:27 UTC 2023 , Edited by admin on Thu Jul 06 23:10:27 UTC 2023
PRIMARY
MESH
C058534
Created by admin on Thu Jul 06 23:10:27 UTC 2023 , Edited by admin on Thu Jul 06 23:10:27 UTC 2023
PRIMARY
SMS_ID
100000082323
Created by admin on Thu Jul 06 23:10:27 UTC 2023 , Edited by admin on Thu Jul 06 23:10:27 UTC 2023
PRIMARY
PUBCHEM
164089
Created by admin on Thu Jul 06 23:10:27 UTC 2023 , Edited by admin on Thu Jul 06 23:10:27 UTC 2023
PRIMARY
ChEMBL
CHEMBL324090
Created by admin on Thu Jul 06 23:10:27 UTC 2023 , Edited by admin on Thu Jul 06 23:10:27 UTC 2023
PRIMARY
EPA CompTox
DTXSID40238163
Created by admin on Thu Jul 06 23:10:27 UTC 2023 , Edited by admin on Thu Jul 06 23:10:27 UTC 2023
PRIMARY
CAS
90402-40-7
Created by admin on Thu Jul 06 23:10:27 UTC 2023 , Edited by admin on Thu Jul 06 23:10:27 UTC 2023
PRIMARY
EVMPD
SUB07358MIG
Created by admin on Thu Jul 06 23:10:27 UTC 2023 , Edited by admin on Thu Jul 06 23:10:27 UTC 2023
PRIMARY
Related Record Type Details
ACTIVE MOIETY