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Details

Stereochemistry ACHIRAL
Molecular Formula C22H25N3O4
Molecular Weight 395.4516
Optical Activity NONE
Defined Stereocenters 0 / 0
E/Z Centers 0
Charge 0

SHOW SMILES / InChI
Structure of ABANOQUIL

SMILES

COC1=CC2=C(CN(CC2)C3=NC4=CC(OC)=C(OC)C=C4C(N)=C3)C=C1OC

InChI

InChIKey=ANZIISNSHPKVRV-UHFFFAOYSA-N
InChI=1S/C22H25N3O4/c1-26-18-7-13-5-6-25(12-14(13)8-19(18)27-2)22-10-16(23)15-9-20(28-3)21(29-4)11-17(15)24-22/h7-11H,5-6,12H2,1-4H3,(H2,23,24)

HIDE SMILES / InChI
Molecular Formula C22H25N3O4
Molecular Weight 395.4516
Charge 0
Count
MOL RATIO 1 MOL RATIO (average)
Stereochemistry ACHIRAL
Additional Stereochemistry No
Defined Stereocenters 0 / 0
E/Z Centers 0
Optical Activity NONE

Description

Abanoquil (UK-52,046), an antiarrhythmic drug, is an alpha 1-adrenoceptor antagonist, has been studied for the treatment of erectile dysfunction.

Approval Year

Unknown
139,594

Targets

Primary TargetPharmacologyConditionPotency
Adrenergic receptor alpha-1
169
Antagonist
2,778

PubMed

Patents

JPS6440425A
3

Sample Use Guides

In Vivo Use Guide
single oral doses of abanoquil 0.25, 0.5 and 1 mg
Route of Administration: Oral
Substance Class Chemical
Record UNII
F738MWY53L
Record Status Validated (UNII)
Record Version
NIH
NCATS
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