Details
| Stereochemistry | ACHIRAL |
| Molecular Formula | C19H25NO |
| Molecular Weight | 283.4079 |
| Optical Activity | ( + / - ) |
| Defined Stereocenters | 0 / 1 |
| E/Z Centers | 0 |
| Charge | 0 |
SHOW SMILES / InChI
SMILES
CCCN(CCC)C1CC2=CC=CC3=CC(O)=CC(C1)=C23
InChI
InChIKey=TWUJBHBRYYTEDL-UHFFFAOYSA-N
InChI=1S/C19H25NO/c1-3-8-20(9-4-2)17-10-14-6-5-7-15-12-18(21)13-16(11-17)19(14)15/h5-7,12-13,17,21H,3-4,8-11H2,1-2H3
| Molecular Formula | C19H25NO |
| Molecular Weight | 283.4079 |
| Charge | 0 |
| Count |
|
| Stereochemistry | RACEMIC |
| Additional Stereochemistry | No |
| Defined Stereocenters | 0 / 1 |
| E/Z Centers | 0 |
| Optical Activity | ( + / - ) |
Alentemol (U-66444B) is a selective dopamine agonist acting at presynaptic receptors to inhibit the release of dopamine. In preclinical studies the compound caused hypothermia in mice and inhibited amphetamine-stimulated omtor activity in mice. U-66444B was investigated by Upjohn Company for the treatment of schizophrenia, but the development of the drug was discontinued.
Approval Year
PubMed
| Title | Date | PubMed |
|---|---|---|
| Determination of alentamol hydrobromide, a novel antipsychotic agent, in human blood plasma and urine by high-performance liquid chromatography with fluorescence detection and solid-phase extraction. | 1991-04-19 |
|
| U-66444B and U-68553B, potent autoreceptor agonists at dopaminergic cell bodies and terminals. | 1990-08 |
Patents
| Substance Class |
Chemical
Created
by
admin
on
Edited
Mon Mar 31 18:24:17 GMT 2025
by
admin
on
Mon Mar 31 18:24:17 GMT 2025
|
| Record UNII |
F6S91MHL3E
|
| Record Status |
Validated (UNII)
|
| Record Version |
|
-
Download
| Name | Type | Language | ||
|---|---|---|---|---|
|
Preferred Name | English | ||
|
Official Name | English | ||
|
Systematic Name | English | ||
|
Systematic Name | English |
| Classification Tree | Code System | Code | ||
|---|---|---|---|---|
|
NCI_THESAURUS |
C66884
Created by
admin on Mon Mar 31 18:24:17 GMT 2025 , Edited by admin on Mon Mar 31 18:24:17 GMT 2025
|
| Code System | Code | Type | Description | ||
|---|---|---|---|---|---|
|
100000087852
Created by
admin on Mon Mar 31 18:24:17 GMT 2025 , Edited by admin on Mon Mar 31 18:24:17 GMT 2025
|
PRIMARY | |||
|
SUB05308MIG
Created by
admin on Mon Mar 31 18:24:17 GMT 2025 , Edited by admin on Mon Mar 31 18:24:17 GMT 2025
|
PRIMARY | |||
|
CHEMBL2104081
Created by
admin on Mon Mar 31 18:24:17 GMT 2025 , Edited by admin on Mon Mar 31 18:24:17 GMT 2025
|
PRIMARY | |||
|
Alentemol
Created by
admin on Mon Mar 31 18:24:17 GMT 2025 , Edited by admin on Mon Mar 31 18:24:17 GMT 2025
|
PRIMARY | |||
|
112891-97-1
Created by
admin on Mon Mar 31 18:24:17 GMT 2025 , Edited by admin on Mon Mar 31 18:24:17 GMT 2025
|
PRIMARY | |||
|
6755
Created by
admin on Mon Mar 31 18:24:17 GMT 2025 , Edited by admin on Mon Mar 31 18:24:17 GMT 2025
|
PRIMARY | |||
|
DTXSID80869556
Created by
admin on Mon Mar 31 18:24:17 GMT 2025 , Edited by admin on Mon Mar 31 18:24:17 GMT 2025
|
PRIMARY | |||
|
C77562
Created by
admin on Mon Mar 31 18:24:17 GMT 2025 , Edited by admin on Mon Mar 31 18:24:17 GMT 2025
|
PRIMARY | |||
|
60574
Created by
admin on Mon Mar 31 18:24:17 GMT 2025 , Edited by admin on Mon Mar 31 18:24:17 GMT 2025
|
PRIMARY | |||
|
F6S91MHL3E
Created by
admin on Mon Mar 31 18:24:17 GMT 2025 , Edited by admin on Mon Mar 31 18:24:17 GMT 2025
|
PRIMARY |
| Related Record | Type | Details | ||
|---|---|---|---|---|
|
|
ACTIVE MOIETY |
