ZINPENTRAXIN ALFA

U.S. Department of Health & Human Services Divider Arrow

National Institutes of Health Divider Arrow

NCATS

Investigational

Approval Year

Substance Class	Protein Created by `admin` on `Mon Mar 31 23:23:43 GMT 2025` Edited by `admin` on `Mon Mar 31 23:23:43 GMT 2025`
Protein Sub Type
Sequence Type	COMPLETE
Record UNII	F68WAH6N5E
Record Status	`Validated (UNII)`
Record Version

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Name

Type

Language

ZINPENTRAXIN ALFA

Official Name

English

PRM-151

Preferred Name

English

SERUM AMYLOID P-COMPONENT, RECOMBINANT

Common Name

English

AMYLOID P COMPONENT, SERUM, RECOMBINANT

Common Name

English

RG-30326

Code

English

Recombinant human Pentraxin-2

Common Name

English

PENTRAXIN 2 (HUMAN)

Common Name

English

Zinpentraxin alfa [WHO-DD]

Common Name

English

zinpentraxin alfa [INN]

Common Name

English

ZINPENTRAXIN ALFA [USAN]

Common Name

English

Human serum amyloid P component (SAP, pentraxin-2), non-covalent cyclic homopentamer, produced in Chinese hamster ovary (CHO) cells, glycoform alfa; serum amyloid P component (APCS, SAP, pentraxin 2, pentaxin 2, PTX2, 9.5S ?-1 glycoprotein), non-covalent

Common Name

English

RECOMBINANT HUMAN SERUM AMYLOID P

Common Name

English

RO-7490677

Code

English

RG6354

Code

English

RG30326

Code

English

PENTRAXIN-2

Common Name

English

Serum amyloid P protein (recombinant human PRM 151)

Common Name

English

RG-6354

Code

English

RO7490677

Code

English

PTX-2

Code

English

Classification Tree Code System Code

FDA ORPHAN DRUG

361111

Created by admin on Mon Mar 31 23:23:43 GMT 2025 , Edited by admin on Mon Mar 31 23:23:43 GMT 2025

FDA ORPHAN DRUG

416013

Created by admin on Mon Mar 31 23:23:43 GMT 2025 , Edited by admin on Mon Mar 31 23:23:43 GMT 2025

EU-Orphan Drug

EU/3/09/674

Created by admin on Mon Mar 31 23:23:43 GMT 2025 , Edited by admin on Mon Mar 31 23:23:43 GMT 2025

Code System Code Type Description

UNIPROT

P02743

Created by admin on Mon Mar 31 23:23:43 GMT 2025 , Edited by admin on Mon Mar 31 23:23:43 GMT 2025

PRIMARY

NCI_THESAURUS

C113177

Created by admin on Mon Mar 31 23:23:43 GMT 2025 , Edited by admin on Mon Mar 31 23:23:43 GMT 2025

PRIMARY

CAS

1387453-03-3

Created by admin on Mon Mar 31 23:23:43 GMT 2025 , Edited by admin on Mon Mar 31 23:23:43 GMT 2025

PRIMARY

EVMPD

SUB181451

Created by admin on Mon Mar 31 23:23:43 GMT 2025 , Edited by admin on Mon Mar 31 23:23:43 GMT 2025

PRIMARY

FDA UNII

F68WAH6N5E

Created by admin on Mon Mar 31 23:23:43 GMT 2025 , Edited by admin on Mon Mar 31 23:23:43 GMT 2025

PRIMARY

DRUG BANK

DB14852

Created by admin on Mon Mar 31 23:23:43 GMT 2025 , Edited by admin on Mon Mar 31 23:23:43 GMT 2025

PRIMARY

SMS_ID

100000167062

Created by admin on Mon Mar 31 23:23:43 GMT 2025 , Edited by admin on Mon Mar 31 23:23:43 GMT 2025

PRIMARY

INN

11816

Created by admin on Mon Mar 31 23:23:43 GMT 2025 , Edited by admin on Mon Mar 31 23:23:43 GMT 2025

PRIMARY

USAN

KL-86

Created by admin on Mon Mar 31 23:23:43 GMT 2025 , Edited by admin on Mon Mar 31 23:23:43 GMT 2025

PRIMARY

From	To
1_36	1_95
2_36	2_95
3_36	3_95
4_36	4_95
5_36	5_95

Linkage Type	Residue Index
COORDINATION COMPOUND	4_58	4_59	4_136	4_137	4_138	4_148
COORDINATION COMPOUND	5_58	5_59	5_136	5_137	5_138	5_148
COORDINATION COMPOUND	1_58	1_59	1_136	1_137	1_138	1_148
COORDINATION COMPOUND	2_58	2_59	2_136	2_137	2_138	2_148
COORDINATION COMPOUND	3_58	3_59	3_136	3_137	3_138	3_148

Glycosylation Type

MAMMALIAN

Glycosylation Link Type	Site
N	1_32
N	1_110
N	2_32
N	2_110
N	3_32
N	3_110
N	4_32
N	4_110
N	5_32
N	5_110

Related Record Type Details


					F68WAH6N5E

ZINPENTRAXIN ALFA

ACTIVE MOIETY

Amount:

Structural Modifications

Modification Type	Location Site	Location Type	Residue Modified	Extent	Fragment Name	Fragment Approval
AMINO_ACID_SUBSTITUTION	[5_58] [5_59] [5_136] [5_137] [5_138] [5_148]	SITE_SPECIFIC			CALCIUM BINDING DDENQQ-TYPE	6KHF07E33D
AMINO_ACID_SUBSTITUTION	[3_58] [3_59] [3_136] [3_137] [3_138] [3_148]	SITE_SPECIFIC			CALCIUM BINDING DDENQQ-TYPE	6KHF07E33D
AMINO_ACID_SUBSTITUTION	[1_58] [1_59] [1_136] [1_137] [1_138] [1_148]	SITE_SPECIFIC			CALCIUM BINDING DDENQQ-TYPE	6KHF07E33D
AMINO_ACID_SUBSTITUTION	[2_58] [2_59] [2_136] [2_137] [2_138] [2_148]	SITE_SPECIFIC			CALCIUM BINDING DDENQQ-TYPE	6KHF07E33D
AMINO_ACID_SUBSTITUTION	[4_58] [4_59] [4_136] [4_137] [4_138] [4_148]	SITE_SPECIFIC			CALCIUM BINDING DDENQQ-TYPE	6KHF07E33D

Name	Property Type	Amount	Referenced Substance	Defining	Parameters	References
MOL_WEIGHT:NUMBER(CALCULATED)	CHEMICAL
Molecular Formula	CHEMICAL