SPHINGOSINE 1-PHOSPHATE RECEPTOR 3

Substance Class	Protein Created by `admin` on `Sat Dec 16 14:58:37 GMT 2023` Edited by `admin` on `Sat Dec 16 14:58:37 GMT 2023`
Protein Type	RECEPTOR
Protein Sub Type
Sequence Origin	HUMAN
Sequence Type	COMPLETE
Record UNII	F5D2GQ34MY
Record Status	`Validated (UNII)`
Record Version

Name

Type

Language

Common Name

English

ENDOTHELIAL DIFFERENTIATION G-PROTEIN COUPLED RECEPTOR 3

Common Name

English

S1P3

Common Name

English

S1P RECEPTOR EDG-3

Common Name

English

S1P RECEPTOR 3

Common Name

English

S1PR3

Common Name

English

SPHINGOSINE 1-PHOSPHATE RECEPTOR EDG-3

Common Name

English

Code System Code Type Description

UNIPROT

Q99500

Created by admin on Sat Dec 16 14:58:38 GMT 2023 , Edited by admin on Sat Dec 16 14:58:38 GMT 2023

PRIMARY

FDA UNII

F5D2GQ34MY

Created by admin on Sat Dec 16 14:58:38 GMT 2023 , Edited by admin on Sat Dec 16 14:58:38 GMT 2023

PRIMARY

Glycosylation Type

HUMAN

Glycosylation Link Type	Site
N	1_15

Related Record Type Details


					92YDM6122J

AGONIST -> TARGET

Comments:

Phase2 clinical trial results of siponimod and ceralifimod suggest that S1P3 and S1P4 targeting are not needed for therapeutic efficacy.

Amount:

Name	Property Type	Amount	Referenced Substance	Defining	Parameters	References
Molecular Formula	CHEMICAL
MOL_WEIGHT	CHEMICAL