Details
| Stereochemistry | ABSOLUTE |
| Molecular Formula | C18H38NO5P |
| Molecular Weight | 379.4718 |
| Optical Activity | UNSPECIFIED |
| Defined Stereocenters | 2 / 2 |
| E/Z Centers | 1 |
| Charge | 0 |
SHOW SMILES / InChI
SMILES
CCCCCCCCCCCCC\C=C\[C@@H](O)[C@@H](N)COP(O)(O)=O
InChI
InChIKey=DUYSYHSSBDVJSM-KRWOKUGFSA-N
InChI=1S/C18H38NO5P/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-18(20)17(19)16-24-25(21,22)23/h14-15,17-18,20H,2-13,16,19H2,1H3,(H2,21,22,23)/b15-14+/t17-,18+/m0/s1
| Molecular Formula | C18H38NO5P |
| Molecular Weight | 379.4718 |
| Charge | 0 |
| Count |
|
| Stereochemistry | ABSOLUTE |
| Additional Stereochemistry | No |
| Defined Stereocenters | 2 / 2 |
| E/Z Centers | 1 |
| Optical Activity | UNSPECIFIED |
Approval Year
Targets
| Primary Target | Pharmacology | Condition | Potency |
|---|---|---|---|
Target ID: P21453 Gene ID: 1901.0 Gene Symbol: S1PR1 Target Organism: Homo sapiens (Human) |
0.4 nM [IC50] | ||
Target ID: O95136 Gene ID: 9294.0 Gene Symbol: S1PR2 Target Organism: Homo sapiens (Human) |
3.8 nM [EC50] | ||
Target ID: Q99500 Gene ID: 1903.0 Gene Symbol: S1PR3 Target Organism: Homo sapiens (Human) |
0.6 nM [EC50] | ||
Target ID: O95977 Gene ID: 8698.0 Gene Symbol: S1PR4 Target Organism: Homo sapiens (Human) |
67.0 nM [EC50] | ||
Target ID: Q9H228 Gene ID: 53637.0 Gene Symbol: S1PR5 Target Organism: Homo sapiens (Human) |
0.5 nM [EC50] |
| Substance Class |
Chemical
Created
by
admin
on
Edited
Wed Apr 02 17:51:28 GMT 2025
by
admin
on
Wed Apr 02 17:51:28 GMT 2025
|
| Record UNII |
YVE187NJ1U
|
| Record Status |
Validated (UNII)
|
| Record Version |
|
-
Download
| Name | Type | Language | ||
|---|---|---|---|---|
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Preferred Name | English | ||
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Official Name | English | ||
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Common Name | English | ||
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Common Name | English |
| Classification Tree | Code System | Code | ||
|---|---|---|---|---|
|
NCI_THESAURUS |
C68425
Created by
admin on Wed Apr 02 17:51:29 GMT 2025 , Edited by admin on Wed Apr 02 17:51:29 GMT 2025
|
| Code System | Code | Type | Description | ||
|---|---|---|---|---|---|
|
Sphingosine 1-phosphate
Created by
admin on Wed Apr 02 17:51:29 GMT 2025 , Edited by admin on Wed Apr 02 17:51:29 GMT 2025
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PRIMARY | |||
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26993-30-6
Created by
admin on Wed Apr 02 17:51:29 GMT 2025 , Edited by admin on Wed Apr 02 17:51:29 GMT 2025
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PRIMARY | |||
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5283560
Created by
admin on Wed Apr 02 17:51:29 GMT 2025 , Edited by admin on Wed Apr 02 17:51:29 GMT 2025
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PRIMARY | |||
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YVE187NJ1U
Created by
admin on Wed Apr 02 17:51:29 GMT 2025 , Edited by admin on Wed Apr 02 17:51:29 GMT 2025
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PRIMARY | |||
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C126907
Created by
admin on Wed Apr 02 17:51:29 GMT 2025 , Edited by admin on Wed Apr 02 17:51:29 GMT 2025
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PRIMARY | NCIT | ||
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37550
Created by
admin on Wed Apr 02 17:51:29 GMT 2025 , Edited by admin on Wed Apr 02 17:51:29 GMT 2025
|
PRIMARY | |||
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DTXSID4037166
Created by
admin on Wed Apr 02 17:51:29 GMT 2025 , Edited by admin on Wed Apr 02 17:51:29 GMT 2025
|
PRIMARY |
| Related Record | Type | Details | ||
|---|---|---|---|---|
|
TARGET -> AGONIST |
EC50
|
||
|
TARGET -> AGONIST |
EC50
|
||
|
TARGET -> AGONIST |
EC50
|
||
|
|
INHIBITOR -> TARGET |
prevents binding to sphingosine-1-phosphate receptors
|
||
|
TARGET -> AGONIST |
Endogenous ligand. [?-35S]GTP binding assay. Interaction between S1P and S1P1 is thought to promote lymphocyte egress from lymph nodes.
EC50
|
||
|
TARGET -> AGONIST |
EC50
|
||
|
TARGET -> AGONIST |
EC50
|
| Related Record | Type | Details | ||
|---|---|---|---|---|
|
PARENT -> METABOLITE |
|
| Related Record | Type | Details | ||
|---|---|---|---|---|
|
ACTIVE MOIETY |
|
