TRITOQUALINE

Details

Stereochemistry	MIXED
Molecular Formula	C26H32N2O8
Molecular Weight	500.5419
Optical Activity	UNSPECIFIED
Defined Stereocenters	0 / 2
E/Z Centers	0
Charge	0

SHOW SMILES / InChI

Structure Search

SMILES

CCOc1c2c(c(c(c1OCC)OCC)N)C(=O)OC2C3c4c(CCN3C)cc5c(c4OC)OCO5

InChI

InChIKey=IRGJVQIJENCTQF-UHFFFAOYSA-N

InChI=1S/C26H32N2O8/c1-6-31-23-17-16(18(27)24(32-7-2)25(23)33-8-3)26(29)36-21(17)19-15-13(9-10-28(19)4)11-14-20(22(15)30-5)35-12-34-14/h11,19,21H,6-10,12,27H2,1-5H3

HIDE SMILES / InChI

Molecular Formula	C26H32N2O8
Molecular Weight	500.5419
Charge	0
Count

Stereochemistry	MIXED
Additional Stereochemistry	No
Defined Stereocenters	0 / 2
E/Z Centers	0
Optical Activity	UNSPECIFIED

Description
Sources: https://www.sciencedirect.com/science/article/pii/S0335745703000479 | http://sante.lefigaro.fr/medicaments/3052109-hypostamine-100mg-cpr-20

Tritoqualine is an inhibitor of histidine decarboxylase, an enzyme that catalyzes the conversion of histidine to histamine. Tritoqualine does not act on histamine receptors. It was marketed since 1960 for the treatment of allergic conditions and is available under tradename Hypostamine.

Approval Year

PubMed

Title	Date	PubMed

Patents

Substance Class	Chemical Created by `admin` on `Sat Jun 26 10:55:54 UTC 2021` Edited by `admin` on `Sat Jun 26 10:55:54 UTC 2021`
Record UNII	F4MW5166YH
Record Status	`Validated (UNII)`
Record Version

Download

Name

Type

Language

TRITOQUALINE

Official Name

English

HYPOSTAMIN

Brand Name

English

MCI-5011

Code

English

554L

Code

English

TRITOQUALINE [MART.]

Common Name

English

INHIBOSTAMIN

Brand Name

English

L-554

Code

English

HYPOSTAMINE

Brand Name

English

TRITOQUALINE [INN]

Common Name

English

35NZ

Code

English

7-AMINO-4,5,6-TRIETHOXY-3-(5,6,7,8-TETRAHYDRO-4-METHOXY-6-METHYL-1,3-DIOXOLO(4,5-G)ISOQUINOLIN-5-YL)-1(3H)-ISOBENZOFURANONE

Systematic Name

English

TRITOQUALINE [WHO-DD]

Common Name

English

LIVALFA

Brand Name

English

7-AMINO-4,5,6-TRIETHOXY-3-(5,6,7,8-TETRAHYDRO-4-METHOXY-6-METHYL-1,3-DIOXOLO(4,5-G)ISOQUINOLIN-5-YL)PHTHALIDE

Systematic Name

English

TRITOQUALINE [MI]

Common Name

English

TRITOCALINE

Common Name

English

Classification Tree Code System Code

WHO-VATC

QR06AX21