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Details

Stereochemistry MIXED
Molecular Formula C21H24O4
Molecular Weight 340.4129
Optical Activity UNSPECIFIED
Defined Stereocenters 0 / 2
E/Z Centers 0
Charge 0

SHOW SMILES / InChI
Structure of BISPHENOL A DIGLYCIDYL ETHER

SMILES

CC(C)(C1=CC=C(OCC2CO2)C=C1)C3=CC=C(OCC4CO4)C=C3

InChI

InChIKey=LCFVJGUPQDGYKZ-UHFFFAOYSA-N
InChI=1S/C21H24O4/c1-21(2,15-3-7-17(8-4-15)22-11-19-13-24-19)16-5-9-18(10-6-16)23-12-20-14-25-20/h3-10,19-20H,11-14H2,1-2H3

HIDE SMILES / InChI

Molecular Formula C21H24O4
Molecular Weight 340.4129
Charge 0
Count
MOL RATIO 1 MOL RATIO (average)
Stereochemistry MIXED
Additional Stereochemistry No
Defined Stereocenters 0 / 2
E/Z Centers 0
Optical Activity UNSPECIFIED

Description

Bisphenol A diglycidyl ether (BADGE) is a ligand for peroxisome proliferator-activated receptor gamma (PPARgamma); in addition, this compound can antagonize the ability of agonist ligands such as rosiglitazone to activate the transcriptional and adipogenic action of this receptor. The elevation of BADGE concentration in epoxy resins-coated aluminium tubes poses a risk of developing contact dermatitis to patients sensitized to epoxy resins.

Approval Year

Targets

Primary TargetPharmacologyConditionPotency
100.0 µM [IC50]

PubMed

Substance Class Chemical
Record UNII
F3XRM1NX4H
Record Status Validated (UNII)
Record Version