TABILAUTIDE

Details

Stereochemistry	ABSOLUTE
Molecular Formula	C27H49N5O8
Molecular Weight	571.7067
Optical Activity	UNSPECIFIED
Defined Stereocenters	4 / 4
E/Z Centers	0
Charge	0

SHOW SMILES / InChI

Structure Search

SMILES

CCCCCCCCCCCC(=O)N[C@@H](C)C(=O)N[C@H](CCC(=O)N[C@@H](CCC[C@H](N)C(N)=O)C(O)=O)C(O)=O

InChI

InChIKey=TUNXCNXMSJZNPO-XSDIEEQYSA-N

InChI=1S/C27H49N5O8/c1-3-4-5-6-7-8-9-10-11-15-22(33)30-18(2)25(36)32-21(27(39)40)16-17-23(34)31-20(26(37)38)14-12-13-19(28)24(29)35/h18-21H,3-17,28H2,1-2H3,(H2,29,35)(H,30,33)(H,31,34)(H,32,36)(H,37,38)(H,39,40)/t18-,19-,20-,21+/m0/s1

HIDE SMILES / InChI

Molecular Formula	C27H49N5O8
Molecular Weight	571.7067
Charge	0
Count

Stereochemistry	ABSOLUTE
Additional Stereochemistry	No
Defined Stereocenters	4 / 4
E/Z Centers	0
Optical Activity	UNSPECIFIED

Description
Sources: https://www.ncbi.nlm.nih.gov/pubmed/25303221 | https://www.ncbi.nlm.nih.gov/pubmed/3266200 | https://www.ncbi.nlm.nih.gov/pubmed/2754438

Tabilautide (also known as RP 56142) is a tripeptide derivative patented by Rhone-Poulenc Industries S. A. as an immune adjuvant. In preclinical studies, Tabilautide displays potent protective activities against bacterial infections such as K. pneumoniae, L. monocytogenes or S. Typhimurium. Besides that Tabilautide shows antimetastatic activity and induces macrophage activation and enhanced cytotoxicity of natural killer cells in spleen, blood, and liver. These activities correlate with prophylactic and therapeutic effects of Tabilautide on artificial liver metastases of histiocytosarcoma.

Originator

Approval Year

PubMed

Title	Date	PubMed
Mucoadhesive polymers-based film as a carrier system for sublingual delivery of glutathione.	2015-01	25303221

Patents

Substance Class	Chemical Created by `admin` on `Mon Mar 31 18:32:03 GMT 2025` Edited by `admin` on `Mon Mar 31 18:32:03 GMT 2025`
Record UNII	EZ61NB05TG
Record Status	`Validated (UNII)`
Record Version

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Name

Type

Language

tabilautide [INN]

Preferred Name

English

TABILAUTIDE

Official Name

English

Classification Tree Code System Code

NCI_THESAURUS

C308