DEMEXIPTILINE

Possibly Marketed Outside US

Details

Stereochemistry	ACHIRAL
Molecular Formula	C18H18N2O
Molecular Weight	278.3483
Optical Activity	NONE
Defined Stereocenters	0 / 0
E/Z Centers	0
Charge	0

SHOW SMILES / InChI

Structure Search

SMILES

CNCCON=C1C2=C(C=CC=C2)C=CC3=C1C=CC=C3

InChI

InChIKey=SEDQWOMFMIJKCU-UHFFFAOYSA-N

InChI=1S/C18H18N2O/c1-19-12-13-21-20-18-16-8-4-2-6-14(16)10-11-15-7-3-5-9-17(15)18/h2-11,19H,12-13H2,1H3

HIDE SMILES / InChI

Molecular Formula	C18H18N2O
Molecular Weight	278.3483
Charge	0
Count

Stereochemistry	ACHIRAL
Additional Stereochemistry	No
Defined Stereocenters	0 / 0
E/Z Centers	0
Optical Activity	NONE

Description
Sources: http://www.slschofield.com/medicine/psychiatric_drugs_chart.html | https://www.ncbi.nlm.nih.gov/pubmed/7337336 | https://www.ncbi.nlm.nih.gov/pubmed/8370568 | https://coupons.pharmacy/tricyclic-antidepressants/ | https://books.google.ru/books?id=_J2ti4EkYpkC&pg=PA1218&lpg=PA1218&dq=Demexiptiline retrieved from Pharmaceutical Manufacturing Encyclopedia, 3rd Edition By William Andrew Publishing, p. 1218

Demexiptiline (Tinoran, Deparon) is a tricyclic antidepressant, noradrenergic drug. It is a norepinephrine reuptake inhibitor. Deparon was used in France for the treatment of depression.

Originator

Approval Year

PubMed

Title	Date	PubMed
Anti-immobility activity of different antidepressant drugs using the tail suspension test in normal or reserpinized mice.	1993	8370568
[Demexiptiline in the treatment of melancholic states (reflections after 3 years of use)].	1981-11	7337336

Patents

Sample Use Guides

In Vivo Use Guide

Treatment of depression: 50-75mg

Route of Administration: Unknown

Substance Class	Chemical Created by `admin` on `Mon Mar 31 18:20:59 GMT 2025` Edited by `admin` on `Mon Mar 31 18:20:59 GMT 2025`
Record UNII	EYX738UZ5P
Record Status	`Validated (UNII)`
Record Version

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Name

Type

Language

DEMEXIPTILINE

Official Name

English

DEMEXIPTILINE [MI]

Preferred Name

English

demexiptiline [INN]

Common Name

English

5H-DIBENZO(A,D)CYCLOHEPTEN-5-ONE O-(2-(METHYLAMINO)ETHYL)OXIME

Systematic Name

English

Demexiptiline [WHO-DD]

Common Name

English

Classification Tree Code System Code

NCI_THESAURUS

C265