SODIUM-AND CHLORIDE-DEPENDENT CREATINE TRANSPORTER 1

Approval Year

Substance Class	Protein Created by `admin` on `Wed Apr 02 00:43:46 GMT 2025` Edited by `admin` on `Wed Apr 02 00:43:46 GMT 2025`
Protein Type	TRANSPORTER
Protein Sub Type
Sequence Origin	HUMAN
Sequence Type	COMPLETE
Record UNII	EWB0UC2OWD
Record Status	`Validated (UNII)`
Record Version

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Name

Type

Language

SODIUM-AND CHLORIDE-DEPENDENT CREATINE TRANSPORTER 1

Common Name

English

CREATINE TRANSPORTER 1

Preferred Name

English

CT1

Common Name

English

SOLUTE CARRIER FAMILY 6 MEMBER 8

Common Name

English

SLC6A8

Common Name

English

Code System Code Type Description

FDA UNII

EWB0UC2OWD

Created by admin on Wed Apr 02 00:43:46 GMT 2025 , Edited by admin on Wed Apr 02 00:43:46 GMT 2025

PRIMARY

UNIPROT

P48029

Created by admin on Wed Apr 02 00:43:46 GMT 2025 , Edited by admin on Wed Apr 02 00:43:46 GMT 2025

PRIMARY

Glycosylation Type

HUMAN

Glycosylation Link Type	Site
N	1_192
N	1_197
N	1_548

Related Record Type Details


					UL1984YRKA

Ompenaclid

INHIBITOR -> TARGET

Comments:

RGX-202 inhibits phosphocreatine uptake by SLC6a8, thereby reducing intracellular levels of phosphocreatine available for ATP synthesis in tumor cells.

Amount:

Name	Property Type	Amount	Referenced Substance	Defining	Parameters	References
MOL_WEIGHT:NUMBER(CALCULATED)	CHEMICAL