Ompenaclid

Investigational

Details

Stereochemistry	ACHIRAL
Molecular Formula	C4H9N3O2
Molecular Weight	131.1332
Optical Activity	NONE
Defined Stereocenters	0 / 0
E/Z Centers	0
Charge	0

SHOW SMILES / InChI

SMILES

NC(=N)NCCC(O)=O

InChI

InChIKey=KMXXSJLYVJEBHI-UHFFFAOYSA-N

InChI=1S/C4H9N3O2/c5-4(6)7-2-1-3(8)9/h1-2H2,(H,8,9)(H4,5,6,7)

HIDE SMILES / InChI

Molecular Formula	C4H9N3O2
Molecular Weight	131.1332
Charge	0
Count	MOL RATIO 1 MOL RATIO (average)

Stereochemistry	ACHIRAL
Additional Stereochemistry	No
Defined Stereocenters	0 / 0
E/Z Centers	0
Optical Activity	NONE

Approval Year

PubMed

PubMed

Show entries

Title	Date	PubMed
Mitochondrial intermembrane inclusion bodies: the common denominator between human mitochondrial myopathies and creatine depletion, due to impairment of cellular energetics.	1997 Sep	9309701
Synthesis and biological activity of aminoguanidine and diaminoguanidine analogues of the antidiabetic/antiobesity agent 3-guanidinopropionic acid.	2001 Apr 12	11312923
Fiber type and metabolic dependence of T2 increases in stimulated rat muscles.	2001 Feb	11160061
Pseudomonas aeruginosa PAO1 genes for 3-guanidinopropionate and 4-guanidinobutyrate utilization may be derived from a common ancestor.	2005 Dec	16339950
Increased guanidino species in murine and human succinate semialdehyde dehydrogenase (SSADH) deficiency.	2006 Apr	16504488

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Substance Class	Chemical
Record UNII	UL1984YRKA
Record Status	`Validated (UNII)`
Record Version

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Name

Type

Language

Ompenaclid

Official Name

English

3-Guanidinopropanoic acid

Systematic Name

English

ORISTAR GPA

Brand Name

English

AMIDINO BETA-ALANINE [INCI]

Common Name

English

RGX 202 [WHO-DD]

Common Name

English

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Classification Tree

Code System

Code

Chemical

DSLD

1758 (Number of products:1)

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Code System

Code

Type

Description

INN

12181

PRIMARY

PUBCHEM

67701

PRIMARY

EPA CompTox

DTXSID40188795

PRIMARY

WIKIPEDIA

Guanidinopropionic acid

PRIMARY

ECHA (EC/EINECS)

206-530-0

PRIMARY

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Related Record

Type

Details


					EWB0UC2OWD

SODIUM-AND CHLORIDE-DEPENDENT CREATINE TRANSPORTER 1

TARGET -> INHIBITOR

Comments:

RGX-202 inhibits phosphocreatine uptake by SLC6a8, thereby reducing intracellular levels of phosphocreatine available for ATP synthesis in tumor cells.

Amount: