GRISNILIMAB SETARITOX

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National Institutes of Health Divider Arrow

NCATS

Approval Year

Substance Class	Protein Created by `admin` on `Wed Apr 02 01:52:18 GMT 2025` Edited by `admin` on `Wed Apr 02 01:52:18 GMT 2025`
Protein Type	MONOCLONAL ANTIBODY CONJUGATE
Protein Sub Type	IGG2A
Sequence Origin	MOUSE
Sequence Type	COMPLETE
Record UNII	ES6SG61M8L
Record Status	`Validated (UNII)`
Record Version

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Name

Type

Language

IMMUNOGLOBULIN G2A, ANTI-(HUMAN CD7 ANTIGEN) (MUS MUSCULUS MONOCLONAL WT1 .GAMMA.2A-CHAIN), DISULFIDE WITH MUS MUSCULUS MONOCLONAL WT1 .LAMBDA.-CHAIN, DIMER, N6-(4-(1-MERCAPTOETHYL) BENZOYL) 260-DISULFIDE WITH RICIN A CHAIN (METHIONYL) (RECOMBINANT RICIN

Preferred Name

English

GRISNILIMAB SETARITOX

Official Name

English

IMMUNOGLOBULIN G2A-LAMBDA, ANTI-(CD7 (CD7ANTIGEN (P41),GP40, LEU-9, TP41, TP40)), MUS MUSCULUS MONOCLONAL ANTIBODY CONJUGATED TO RICIN TOXIN A (RTA)

Common Name

English

grisnilimab setaritox [INN]

Common Name

English

Classification Tree Code System Code

EU-Orphan Drug

EU/3/05/317

Created by admin on Wed Apr 02 01:52:18 GMT 2025 , Edited by admin on Wed Apr 02 01:52:18 GMT 2025

Code System Code Type Description

INN

11488

Created by admin on Wed Apr 02 01:52:18 GMT 2025 , Edited by admin on Wed Apr 02 01:52:18 GMT 2025

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SMS_ID

300000008870

Created by admin on Wed Apr 02 01:52:18 GMT 2025 , Edited by admin on Wed Apr 02 01:52:18 GMT 2025

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NCI_THESAURUS

C175793

Created by admin on Wed Apr 02 01:52:18 GMT 2025 , Edited by admin on Wed Apr 02 01:52:18 GMT 2025

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CAS

2361013-29-6

Created by admin on Wed Apr 02 01:52:18 GMT 2025 , Edited by admin on Wed Apr 02 01:52:18 GMT 2025

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FDA UNII

ES6SG61M8L

Created by admin on Wed Apr 02 01:52:18 GMT 2025 , Edited by admin on Wed Apr 02 01:52:18 GMT 2025

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From	To
4_137	4_196
4_22	4_90
3_137	3_196
3_22	3_90
2_373	2_431
2_267	2_327
2_150	2_205
2_138	4_214
2_22	2_96
1_373	1_431
1_267	1_327
1_235	2_235
1_233	2_233
1_230	2_230
1_150	1_205
1_138	3_214
1_22	1_96

Glycosylation Link Type	Site
N	1_303
N	2_303

Related Record Type Details


					5ADI68Z0PC

PARENT -> CONJUGATE

Amount:

Structural Modifications

Modification Type	Location Site	Location Type	Residue Modified	Extent	Fragment Name	Fragment Approval
AMINO_ACID_SUBSTITUTION	[1_43] [1_87] [1_215] [1_228] [1_323] [1_332] [1_398] [1_421] [2_43] [2_87] [2_215] [2_228] [2_323] [2_332] [2_398] [2_421] [3_72] [3_113] [3_132] [4_72] [4_113] [4_132]	SITE_SPECIFIC		Amount:	UNSPECIFIED SUBSTANCE	3821597e (not in database)
AMINO_ACID_SUBSTITUTION	[1_1] [2_1] [3_1] [4_1]	N-TERMINUS			PIDOLIC ACID	SZB83O1W42
AMINO ACID REMOVAL	[1_453] [2_453]	C-TERMINUS			LYSINE	K3Z4F929H6

Name	Property Type	Amount	Referenced Substance	Defining	Parameters	References
MOL_WEIGHT:NUMBER(CALCULATED)	CHEMICAL
Molecular Formula	CHEMICAL