U.S. Department of Health & Human Services Divider Arrow National Institutes of Health Divider Arrow NCATS

Details

Stereochemistry RACEMIC
Molecular Formula C15H23N
Molecular Weight 217.3498
Optical Activity ( + / - )
Defined Stereocenters 0 / 1
E/Z Centers 0
Charge 0

SHOW SMILES / InChI
Structure of PROLINTANE

SMILES

CCCC(CC1=CC=CC=C1)N2CCCC2

InChI

InChIKey=OJCPSBCUMRIPFL-UHFFFAOYSA-N
InChI=1S/C15H23N/c1-2-8-15(16-11-6-7-12-16)13-14-9-4-3-5-10-14/h3-5,9-10,15H,2,6-8,11-13H2,1H3

HIDE SMILES / InChI

Molecular Formula C15H23N
Molecular Weight 217.3498
Charge 0
Count
Stereochemistry RACEMIC
Additional Stereochemistry No
Defined Stereocenters 0 / 1
E/Z Centers 0
Optical Activity ( + / - )

Prolintane is an amphetamine-related CNS stimulant and norepinephrine-dopamine reuptake inhibitor that has been used for the treatment of narcolepsy and attention deficit hyperactivity disorder in Africa, Australia, and Europe. Under the trade-name "Katovit", prolintane was commercialized by the Spanish pharmaceutical company, FHER. Katovit was sold until 2001 and was most often used by students and workers as a stimulant to provide energy, promote alertness and concentration. The use of prolintane as a doping agent in athletics has been noted worldwide. Prolintane, like many amphetamine derivatives, increases the concentration of dopamine in the synaptic cleft. Adverse effects of the drug include insomnia, nervousness, irritability, and dizziness. Overdoses of prolintane may cause hallucinations, psychosis, and death. Individuals who abuse prolintane risk becoming dependent as tolerance may develop.

Approval Year

PubMed

PubMed

TitleDatePubMed
Visual hallucinations induced by the combination of prolintane and diphenhydramine.
2002 Jan
Application of comprehensive two-dimensional gas chromatography to drugs analysis in doping control.
2003 Jun 6
[Sleeplessness. Helping with paradoxical medication].
2005 Dec 8
Substance Class Chemical
Created
by admin
on Fri Dec 15 19:13:37 GMT 2023
Edited
by admin
on Fri Dec 15 19:13:37 GMT 2023
Record UNII
EM4YZW677H
Record Status Validated (UNII)
Record Version
  • Download
Name Type Language
PROLINTANE
INN   MI   WHO-DD  
INN  
Official Name English
PHENYLPYRROLIDINOPENTANE
Systematic Name English
Prolintane [WHO-DD]
Common Name English
prolintane [INN]
Common Name English
PYRROLIDINE, 1-(1-(PHENYLMETHYL)BUTYL)-
Systematic Name English
PYRROLIDINE, 1-(1-BENZYLBUTYL)-
Systematic Name English
PROLINTANE [MI]
Common Name English
PROLINTAN
Common Name English
1-(.ALPHA.-PROPYLPHENETHYL)PYRROLIDINE
Systematic Name English
1-PHENYL-2-PYRROLIDINYLPENTANE
Systematic Name English
Classification Tree Code System Code
WHO-ATC N06BX14
Created by admin on Fri Dec 15 19:13:37 GMT 2023 , Edited by admin on Fri Dec 15 19:13:37 GMT 2023
WHO-VATC QN06BX14
Created by admin on Fri Dec 15 19:13:37 GMT 2023 , Edited by admin on Fri Dec 15 19:13:37 GMT 2023
Code System Code Type Description
WIKIPEDIA
PROLINTANE
Created by admin on Fri Dec 15 19:13:37 GMT 2023 , Edited by admin on Fri Dec 15 19:13:37 GMT 2023
PRIMARY
EVMPD
SUB10083MIG
Created by admin on Fri Dec 15 19:13:37 GMT 2023 , Edited by admin on Fri Dec 15 19:13:37 GMT 2023
PRIMARY
CAS
493-92-5
Created by admin on Fri Dec 15 19:13:37 GMT 2023 , Edited by admin on Fri Dec 15 19:13:37 GMT 2023
PRIMARY
SMS_ID
100000081144
Created by admin on Fri Dec 15 19:13:37 GMT 2023 , Edited by admin on Fri Dec 15 19:13:37 GMT 2023
PRIMARY
MERCK INDEX
m9166
Created by admin on Fri Dec 15 19:13:37 GMT 2023 , Edited by admin on Fri Dec 15 19:13:37 GMT 2023
PRIMARY Merck Index
INN
1171
Created by admin on Fri Dec 15 19:13:37 GMT 2023 , Edited by admin on Fri Dec 15 19:13:37 GMT 2023
PRIMARY
CAS
140145-74-0
Created by admin on Fri Dec 15 19:13:37 GMT 2023 , Edited by admin on Fri Dec 15 19:13:37 GMT 2023
SUPERSEDED
FDA UNII
EM4YZW677H
Created by admin on Fri Dec 15 19:13:37 GMT 2023 , Edited by admin on Fri Dec 15 19:13:37 GMT 2023
PRIMARY
DRUG BANK
DB13438
Created by admin on Fri Dec 15 19:13:37 GMT 2023 , Edited by admin on Fri Dec 15 19:13:37 GMT 2023
PRIMARY
EPA CompTox
DTXSID70862031
Created by admin on Fri Dec 15 19:13:37 GMT 2023 , Edited by admin on Fri Dec 15 19:13:37 GMT 2023
PRIMARY
RXCUI
34604
Created by admin on Fri Dec 15 19:13:37 GMT 2023 , Edited by admin on Fri Dec 15 19:13:37 GMT 2023
PRIMARY RxNorm
MESH
C005598
Created by admin on Fri Dec 15 19:13:37 GMT 2023 , Edited by admin on Fri Dec 15 19:13:37 GMT 2023
PRIMARY
NCI_THESAURUS
C170358
Created by admin on Fri Dec 15 19:13:37 GMT 2023 , Edited by admin on Fri Dec 15 19:13:37 GMT 2023
PRIMARY
PUBCHEM
14592
Created by admin on Fri Dec 15 19:13:37 GMT 2023 , Edited by admin on Fri Dec 15 19:13:37 GMT 2023
PRIMARY
ChEMBL
CHEMBL2111047
Created by admin on Fri Dec 15 19:13:37 GMT 2023 , Edited by admin on Fri Dec 15 19:13:37 GMT 2023
PRIMARY
DRUG CENTRAL
2283
Created by admin on Fri Dec 15 19:13:37 GMT 2023 , Edited by admin on Fri Dec 15 19:13:37 GMT 2023
PRIMARY
ECHA (EC/EINECS)
207-784-5
Created by admin on Fri Dec 15 19:13:37 GMT 2023 , Edited by admin on Fri Dec 15 19:13:37 GMT 2023
PRIMARY
Related Record Type Details
SALT/SOLVATE -> PARENT
Related Record Type Details
METABOLITE -> PARENT
Related Record Type Details
ACTIVE MOIETY