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Details

Stereochemistry ACHIRAL
Molecular Formula C6H5O7.3C5H14NO
Molecular Weight 501.6128
Optical Activity NONE
Defined Stereocenters 0 / 0
E/Z Centers 0
Charge 0

SHOW SMILES / InChI
Structure of TRICHOLINE CITRATE

SMILES

C(C(=O)[O-])C(CC(=O)[O-])(C(=O)[O-])O.C[N+](C)(C)CCO.C[N+](C)(C)CCO.C[N+](C)(C)CCO

InChI

InChIKey=RPERJPYDELTDMR-UHFFFAOYSA-K
InChI=1S/C6H8O7.3C5H14NO/c7-3(8)1-6(13,5(11)12)2-4(9)10;3*1-6(2,3)4-5-7/h13H,1-2H2,(H,7,8)(H,9,10)(H,11,12);3*7H,4-5H2,1-3H3/q;3*+1/p-3

HIDE SMILES / InChI

Molecular Formula C6H8O7
Molecular Weight 192.1238
Charge 0
Count
Stereochemistry ACHIRAL
Additional Stereochemistry No
Defined Stereocenters 0 / 0
E/Z Centers 0
Optical Activity NONE

Molecular Formula C5H13NO
Molecular Weight 103.163
Charge 0
Count
Stereochemistry RACEMIC
Additional Stereochemistry No
Defined Stereocenters 0 / 0
E/Z Centers 0
Optical Activity NONE

TRICHOLINE CITRATE is indicated for the treatment and management of hepatic disorders and asthma symptoms in adults. It exerts lipotropic action in the hepatic cells. It also can lower the symptoms of asthma and reducing the pro-inflammatory and inflammatory mediators of the leukotriene pathway.

Approval Year

Conditions

Conditions

ConditionModalityTargetsHighest PhaseProduct
Primary
Cypron

Approved Use

Cyproheptadine Tricholine Citrate & Sorbitol Syrup is used for the treatment, control, prevention, & improvement of the following diseases, conditions and symptoms: · Occasional Constipation · Liver Disorders · Asthma Symptoms In Adults · Allergic Reactions · Seasonal Allergies · Mild And Uncomplicated Hives
Primary
Cypron

Approved Use

Cyproheptadine Tricholine Citrate & Sorbitol Syrup is used for the treatment, control, prevention, & improvement of the following diseases, conditions and symptoms: · Occasional Constipation · Liver Disorders · Asthma Symptoms In Adults · Allergic Reactions · Seasonal Allergies · Mild And Uncomplicated Hives
Overview

Overview

CYP3A4CYP2C9CYP2D6hERG



OverviewOther

Other InhibitorOther SubstrateOther Inducer









Drug as perpetrator​

Drug as perpetrator​

TargetModalityActivityMetaboliteClinical evidence
moderate
moderate
moderate
no [Activation >10 uM]
no [Activation >10 uM]
no [Activation >10 uM]
no [Activation >10 uM]
no [Activation >10 uM]
no
yes
Drug as victim
Substance Class Chemical
Created
by admin
on Sat Jun 26 03:57:29 UTC 2021
Edited
by admin
on Sat Jun 26 03:57:29 UTC 2021
Record UNII
EH8N140TJ7
Record Status Validated (UNII)
Record Version
  • Download
Name Type Language
TRICHOLINE CITRATE
WHO-DD  
Common Name English
ETHANAMINIUM, 2-HYDROXY-N,N,N-TRIMETHYL-, SALT WITH 2-HYDROXY-1,2,3-PROPANETRICARBOXYLIC ACID (3:1)
Common Name English
TRICHOLINE CITRATE [WHO-DD]
Common Name English
ETHANAMINIUM, 2-HYDROXY-N,N,N-TRIMETHYL-, 2-HYDROXY-1,2,3-PROPANETRICARBOXYLATE (3:1)
Systematic Name English
CHOLINE CITRATE [WHO-DD]
Common Name English
CHOLINE CITRATE
WHO-DD  
Systematic Name English
Code System Code Type Description
PUBCHEM
11024
Created by admin on Sat Jun 26 03:57:29 UTC 2021 , Edited by admin on Sat Jun 26 03:57:29 UTC 2021
PRIMARY
RXCUI
2453
Created by admin on Sat Jun 26 03:57:29 UTC 2021 , Edited by admin on Sat Jun 26 03:57:29 UTC 2021
PRIMARY RxNorm
ECHA (EC/EINECS)
208-907-5
Created by admin on Sat Jun 26 03:57:29 UTC 2021 , Edited by admin on Sat Jun 26 03:57:29 UTC 2021
PRIMARY
CAS
546-63-4
Created by admin on Sat Jun 26 03:57:29 UTC 2021 , Edited by admin on Sat Jun 26 03:57:29 UTC 2021
PRIMARY
EPA CompTox
546-63-4
Created by admin on Sat Jun 26 03:57:29 UTC 2021 , Edited by admin on Sat Jun 26 03:57:29 UTC 2021
PRIMARY
FDA UNII
EH8N140TJ7
Created by admin on Sat Jun 26 03:57:29 UTC 2021 , Edited by admin on Sat Jun 26 03:57:29 UTC 2021
PRIMARY
EVMPD
SUB13351MIG
Created by admin on Sat Jun 26 03:57:29 UTC 2021 , Edited by admin on Sat Jun 26 03:57:29 UTC 2021
PRIMARY
Related Record Type Details
PARENT -> SALT/SOLVATE
PARENT -> SALT/SOLVATE