Details
| Stereochemistry | ACHIRAL |
| Molecular Formula | C11H15NO2 |
| Molecular Weight | 193.2423 |
| Optical Activity | NONE |
| Defined Stereocenters | 0 / 0 |
| E/Z Centers | 0 |
| Charge | 0 |
SHOW SMILES / InChI
SMILES
CCCCOC(=O)C1=CC=C(N)C=C1
InChI
InChIKey=IUWVALYLNVXWKX-UHFFFAOYSA-N
InChI=1S/C11H15NO2/c1-2-3-8-14-11(13)9-4-6-10(12)7-5-9/h4-7H,2-3,8,12H2,1H3
| Molecular Formula | C11H15NO2 |
| Molecular Weight | 193.2423 |
| Charge | 0 |
| Count |
|
| Stereochemistry | ACHIRAL |
| Additional Stereochemistry | No |
| Defined Stereocenters | 0 / 0 |
| E/Z Centers | 0 |
| Optical Activity | NONE |
DescriptionSources: https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=89f262a4-a41b-41d7-806b-61b9b89542f0Curator's Comment: description was created based on several sources, including:
https://en.wikipedia.org/wiki/Butamben
Sources: https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=89f262a4-a41b-41d7-806b-61b9b89542f0
Curator's Comment: description was created based on several sources, including:
https://en.wikipedia.org/wiki/Butamben
Butamben is a local anesthetic. It is the ester of 4-aminobenzoic acid and butanol. It is one of three components in the topical anesthetic Cetacaine. The onset of Cetacaine-produced anesthesia is rapid (approximately 30 seconds) and the duration of anesthesia is typically 30-60 minutes, when used as directed. This effect is due to the rapid onset, but short duration of action of Benzocaine coupled with the slow onset, but extended duration of Tetracaine HCI and bridged by the intermediate action of Butamben.
Approval Year
PubMed
| Title | Date | PubMed |
|---|---|---|
| Kv1.1 channels of dorsal root ganglion neurons are inhibited by n-butyl-p-aminobenzoate, a promising anesthetic for the treatment of chronic pain. | 2003 Feb |
|
| Prediction of estrogen receptor agonists and characterization of associated molecular descriptors by statistical learning methods. | 2006 Nov |
|
| The evolution of farnesoid X, vitamin D, and pregnane X receptors: insights from the green-spotted pufferfish (Tetraodon nigriviridis) and other non-mammalian species. | 2011 Feb 3 |
Patents
Sample Use Guides
Cetacaine Spray: approximately one second or less for normal anesthesia
Cetacaine Liquid: 200 mg (approximately 0.2 mL) with a cotton applicator or directly to tissue
Cetacaine Gel: 200 mg of gel (a bead approximately 1/4 to 1/2 inches long) by gently depressing the pump
Route of Administration:
Topical
| Substance Class |
Chemical
Created
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Fri Dec 15 15:21:56 UTC 2023
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Fri Dec 15 15:21:56 UTC 2023
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| Record UNII |
EFW857872Q
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Validated (UNII)
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NCI_THESAURUS |
C245
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C75086
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202-317-1
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EFW857872Q
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1081501
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3051
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BUTAMBEN
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EFW857872Q
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m2785
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CHEMBL127516
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SUB13138MIG
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94-25-7
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19861
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SALT/SOLVATE -> PARENT |
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IMPURITY -> PARENT |
CHROMATOGRAPHIC PURITY (HPLC/UV)
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ACTIVE MOIETY |
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