DISTEAROYLPHOSPHATIDYLCHOLINE, DL-

Details

Stereochemistry	RACEMIC
Molecular Formula	C44H88NO8P
Molecular Weight	790.1452
Optical Activity	( + / - )
Defined Stereocenters	0 / 1
E/Z Centers	0
Charge	0

SHOW SMILES / InChI

Structure of DISTEAROYLPHOSPHATIDYLCHOLINE, DL-

Structure Search

SMILES

CCCCCCCCCCCCCCCCCC(=O)OCC(COP([O-])(=O)OCC[N+](C)(C)C)OC(=O)CCCCCCCCCCCCCCCCC

InChI

InChIKey=NRJAVPSFFCBXDT-UHFFFAOYSA-N

InChI=1S/C44H88NO8P/c1-6-8-10-12-14-16-18-20-22-24-26-28-30-32-34-36-43(46)50-40-42(41-52-54(48,49)51-39-38-45(3,4)5)53-44(47)37-35-33-31-29-27-25-23-21-19-17-15-13-11-9-7-2/h42H,6-41H2,1-5H3

HIDE SMILES / InChI

Molecular Formula	C44H88NO8P
Molecular Weight	790.1452
Charge	0
Count

Stereochemistry	MIXED
Additional Stereochemistry	No
Defined Stereocenters	0 / 1
E/Z Centers	0
Optical Activity	( + / - )

Description
Sources: https://www.accessdata.fda.gov/drugsatfda_docs/label/2016/203684s002lbl.pdf | https://imaging.bracco.com/us-en/products/contrast-enhanced-ultrasound/lumason

DISTEAROYLPHOSPHATIDYLCHOLINE, DL- (DSPC) is a component of LUMASON® (sulfur hexafluoride lipid-type A microspheres). It is an ultrasound contrast agent indicated for use in the heart echocardiography and in ultrasonography of the liver and the urinary tract. The sulfur hexafluoride lipid microspheres are composed of SF6 gas in the core surrounded by an outer shell monolayer of phospholipids such as DSPC.

Approval Year

Conditions

Condition	Modality	Highest Phase	Product
Vesicoureteral reflux 4 Sources: https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=7c679424-c3f7-ed02-892f-20ca0d775089#section-1	Diagnostic	Approved 8429	LUMASON Approved Use Lumason is an ultrasound contrast agent indicated for use - in echocardiography to opacify the left ventricular chamber and to improve the delineation of the left ventricular endocardial border in adult patients with suboptimal echocardiograms - in ultrasonography of the liver for characterization of focal liver lesions in adult and pediatric patients - in ultrasonography of the urinary tract for the evaluation of suspected or known vesicoureteral reflux in pediatric patients Launch Date 2014
Heart Disease 2 Sources: https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=7c679424-c3f7-ed02-892f-20ca0d775089#section-1	Diagnostic	Approved 8429	LUMASON Approved Use Lumason is an ultrasound contrast agent indicated for use - in echocardiography to opacify the left ventricular chamber and to improve the delineation of the left ventricular endocardial border in adult patients with suboptimal echocardiograms - in ultrasonography of the liver for characterization of focal liver lesions in adult and pediatric patients - in ultrasonography of the urinary tract for the evaluation of suspected or known vesicoureteral reflux in pediatric patients Launch Date 2014
Focal liver lesions 2 Sources: https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=7c679424-c3f7-ed02-892f-20ca0d775089#section-1	Diagnostic	Approved 8429	LUMASON Approved Use Lumason is an ultrasound contrast agent indicated for use - in echocardiography to opacify the left ventricular chamber and to improve the delineation of the left ventricular endocardial border in adult patients with suboptimal echocardiograms - in ultrasonography of the liver for characterization of focal liver lesions in adult and pediatric patients - in ultrasonography of the urinary tract for the evaluation of suspected or known vesicoureteral reflux in pediatric patients Launch Date 2014

Sample Use Guides

In Vivo Use Guide

Echocardiography: After reconstitution, administer LUMASON® 2 mL as an intravenous injection in adult patients. Ultrasonography of the liver in adults: After reconstitution, administer LUMASON® 2.4 mL as an intravenous injection.

Route of Administration: Intravenous

Substance Class	Chemical Created by `admin` on `Fri Dec 15 15:19:26 GMT 2023` Edited by `admin` on `Fri Dec 15 15:19:26 GMT 2023`
Record UNII	EAG959U971
Record Status	`Validated (UNII)`
Record Version

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Name

Type

Language

DISTEAROYLPHOSPHATIDYLCHOLINE, DL-

Common Name

English

1,2-DISTEAROYLLECITHIN

Common Name

English

1,2-DISTEAROYL PHOSPHATIDYLCHOLINE, (±)-

Common Name

English

1,2-DISTEAROYL-DL-PHOSPHATIDYLCHOLINE

Common Name

English

DSPC DL-

Common Name

English

DIOCTADECANOYL PHOSPHATIDYLCHOLINE

Common Name

English

Code System Code Type Description

CAS

4539-70-2