1,2-DISTEAROYL-SN-GLYCERO-3-PHOSPHOCHOLINE

Details

Stereochemistry	ABSOLUTE
Molecular Formula	C44H88NO8P
Molecular Weight	790.1452
Optical Activity	UNSPECIFIED
Defined Stereocenters	1 / 1
E/Z Centers	0
Charge	0

SHOW SMILES / InChI

Structure of 1,2-DISTEAROYL-SN-GLYCERO-3-PHOSPHOCHOLINE

Structure Search

SMILES

CCCCCCCCCCCCCCCCCC(=O)OC[C@H](COP([O-])(=O)OCC[N+](C)(C)C)OC(=O)CCCCCCCCCCCCCCCCC

InChI

InChIKey=NRJAVPSFFCBXDT-HUESYALOSA-N

InChI=1S/C44H88NO8P/c1-6-8-10-12-14-16-18-20-22-24-26-28-30-32-34-36-43(46)50-40-42(41-52-54(48,49)51-39-38-45(3,4)5)53-44(47)37-35-33-31-29-27-25-23-21-19-17-15-13-11-9-7-2/h42H,6-41H2,1-5H3/t42-/m1/s1

HIDE SMILES / InChI

Molecular Formula	C44H88NO8P
Molecular Weight	790.1452
Charge	0
Count

Stereochemistry	EPIMERIC
Additional Stereochemistry	No
Defined Stereocenters	1 / 1
E/Z Centers	0
Optical Activity	UNSPECIFIED

Description
Sources: https://www.rxlist.com/tobi-podhaler-drug.htm | https://www.ncbi.nlm.nih.gov/pubmed/27469574

1,2-distearoyl-sn-glycero-3-phosphocholine (DSPC) a non-pyrogenic phospholipid, is used to produce liposomes that are capable of being loaded with a molecule of choice. This compound is also used as an inactive ingredient of drugs, e.g., for TOBI PODHALER which is indicated for the management of cystic fibrosis patients with Pseudomonas aeruginosa.

Approval Year

PubMed

Title	Date	PubMed
Interfacial molecular interactions based on the conformation recognition between the insoluble antitumor drug AD-1 and DSPC.	2016 Oct 1	27469574

Patents

Substance Class	Chemical Created by `admin` on `Fri Dec 15 15:16:38 GMT 2023` Edited by `admin` on `Fri Dec 15 15:16:38 GMT 2023`
Record UNII	043IPI2M0K
Record Status	`Validated (UNII)`
Record Version

Download

Name

Type

Language

1,2-DISTEAROYL-SN-GLYCERO-3-PHOSPHOCHOLINE

Common Name

English

DISTEAROYL-SN-GLYCERO-3-PHOSPHOCHOLINE

Common Name

English

1,2-DISTEAROYL-SN-GLYCERO-3-PHOSPHOCHOLINE (DSPC)

Common Name

English

DISTEAROYL GLYCEROPHOSPHOCHOLINE [INCI]

Common Name

English

L-DISTEAROYLLECITHIN

Common Name

English

DISTEAROYL-L-.ALPHA.-LECITHIN

Common Name

English

DISTEAROYL GLYCEROPHOSPHOCHOLINE

Official Name

English

DSPC R-ISOMER

Common Name

English

NSC-725285

Code

English

DSPC

Common Name

English

1,2-DISTEARIN SN-3-PHOSPHORYLCHOLINE

Common Name

English

1,2-DISTEAROYL-SN-GLYCERO-3-PHOSPHOCHOLINE [II]

Common Name

English

1,2-DIASTEAROYL-SN-GLYCERO-3-PHOSPHOCHOLINE

Common Name

English

3,5,9-TRIOXA-4-PHOSPHAHEPTACOSAN-1-AMINIUM, 4-HYDROXY-N,N,N-TRIMETHYL-10-OXO-7-((1-OXOOCTADECYL)OXY)-, INNER SALT, 4-OXIDE, (7R)-

Common Name

English

Code System Code Type Description

NSC

725285