ALUMINUM HYDROXIDE-GLYCINE (2:1)

US Approved OTC

First approved in 1945

Details

Stereochemistry	ACHIRAL
Molecular Formula	C2H5NO2.2Al.6HO
Molecular Weight	231.0737
Optical Activity	NONE
Defined Stereocenters	0 / 0
E/Z Centers	0
Charge	0

SHOW SMILES / InChI

Structure of ALUMINUM HYDROXIDE-GLYCINE (2:1)

Structure Search

SMILES

[OH-].[OH-].[OH-].[OH-].[OH-].[OH-].[Al+3].[Al+3].NCC(O)=O

InChI

InChIKey=IEDTVAKYAQVPRQ-UHFFFAOYSA-H

InChI=1S/C2H5NO2.2Al.6H2O/c3-1-2(4)5;;;;;;;;/h1,3H2,(H,4,5);;;6*1H2/q;2*+3;;;;;;/p-6

HIDE SMILES / InChI

Molecular Formula	HO
Molecular Weight	17.0073
Charge	-1
Count

Stereochemistry	ACHIRAL
Additional Stereochemistry	No
Defined Stereocenters	0 / 0
E/Z Centers	0
Optical Activity	NONE

Molecular Formula	C2H5NO2
Molecular Weight	75.0666
Charge	0
Count

Stereochemistry	ACHIRAL
Additional Stereochemistry	No
Defined Stereocenters	0 / 0
E/Z Centers	0
Optical Activity	NONE

Molecular Formula	Al
Molecular Weight	26.9815
Charge	3
Count

Stereochemistry	ACHIRAL
Additional Stereochemistry	No
Defined Stereocenters	0 / 0
E/Z Centers	0
Optical Activity	NONE

Description
Sources: https://www.ncbi.nlm.nih.gov/pubmed/923767 | https://www.ncbi.nlm.nih.gov/pubmed/13518053

There is not much information related to the medical application of ALUMINIUM TRIGLYCINATE, also known as ALUMINIUM AMINOACETATE. Nevertheless, some articles are describing the antacid properties of this substance and its application in the treatment of peptic ulcer.

Approval Year

Conditions

Condition	Modality	Targets	Highest Phase	Product
peptic ulcer 4 Sources: https://www.ncbi.nlm.nih.gov/pubmed/13518053	Primary		Basic research	Unknown Approved Use Unknown

PubMed

Title	Date	PubMed
[Experimental and clinical evaluation of aluminum glycinate, a new intragastric buffer solution for achievement of prolonged physiological pH value].	1955 Aug 26	13258418
[Compression force and in-vitro antacid activity of aluminium hydroxide and aluminium glycinate tablets].	1977 Nov	923767
Osteomalacia from Al and Mg antacids. Report of a case of bilateral hip fracture.	1989 Jun	2750515
Gene expression in primary cultured astrocytes affected by aluminum: alteration of chaperons involved in protein folding.	2011 Jan	21432213

Sample Use Guides

In Vivo Use Guide

Unknown

Route of Administration: Unknown

In Vitro Use Guide

Unknown

Substance Class	Chemical Created by `admin` on `Fri Dec 15 15:17:41 UTC 2023` Edited by `admin` on `Fri Dec 15 15:17:41 UTC 2023`
Record UNII	E9L1NA800E
Record Status	`Validated (UNII)`
Record Version

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Name

Type

Language

ALUMINUM HYDROXIDE-GLYCINE (2:1)

Common Name

English

ALUMINIUM HYDROXIDE-GLYCINE (2:1)

Common Name

English

Code System Code Type Description

PUBCHEM

73415786

Created by admin on Fri Dec 15 15:17:41 UTC 2023 , Edited by admin on Fri Dec 15 15:17:41 UTC 2023

PRIMARY

FDA UNII

E9L1NA800E

Created by admin on Fri Dec 15 15:17:41 UTC 2023 , Edited by admin on Fri Dec 15 15:17:41 UTC 2023

PRIMARY

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