U.S. Department of Health & Human Services Divider Arrow National Institutes of Health Divider Arrow NCATS

Approval Year

Substance Class Protein
Created
by admin
on Sat Dec 16 14:26:32 GMT 2023
Edited
by admin
on Sat Dec 16 14:26:32 GMT 2023
Protein Type MONOCLONAL ANTIBODY CONJUGATE
Protein Sub Type IGG1
Sequence Origin HUMANIZED MOUSE
Sequence Type COMPLETE
Record UNII
E8US1SQ3B5
Record Status Validated (UNII)
Record Version
  • Download
Name Type Language
Upinitatug Rilsodotin
INN  
Official Name English
Immunoglobulin G1 [de-450-lysine], anti-(human sodium-dependent phosphate transport protein 2B) (human-Mus musculus monoclonal XMT-1535 γ1-chain), disulfide with human-Mus musculus monoclonal XMT-1535 κ-chain, dimer, thioether with N-(2-carboxyethyl)ca
Common Name English
XMT-1536
Code English
ANTIBODY-DRUG CONJUGATE ADC XMT-1536
Common Name English
Upifitamab Rilsodotin
Common Name English
upinitatug rilsodotin [INN]
Common Name English
Q4MDA7821L
Code English
ANTI-NAPI2B ADC XMT-1536
Common Name English
immunoglobulin G1-kappa, anti-[Homo sapiens SLC34A2 (solute carrier family 34 sodium phosphate member 2, sodium/phosphate cotransporter 2B, NaPi2b, NaPi3b, NAPI-3B)], monoclonal antibody, conjugated, via a thioether bond, to 3 to 5 flexible polymers PHF-
Common Name English
ANTI-NAPI2B/AURISTATIN F-HPA ADC XMT-1536
Common Name English
Code System Code Type Description
INN
11318
Created by admin on Sat Dec 16 14:26:32 GMT 2023 , Edited by admin on Sat Dec 16 14:26:32 GMT 2023
PRIMARY
NCI_THESAURUS
C147577
Created by admin on Sat Dec 16 14:26:32 GMT 2023 , Edited by admin on Sat Dec 16 14:26:32 GMT 2023
PRIMARY
FDA UNII
E8US1SQ3B5
Created by admin on Sat Dec 16 14:26:32 GMT 2023 , Edited by admin on Sat Dec 16 14:26:32 GMT 2023
PRIMARY
CAS
2254119-00-9
Created by admin on Sat Dec 16 14:26:32 GMT 2023 , Edited by admin on Sat Dec 16 14:26:32 GMT 2023
PRIMARY
From To
1_22 1_96
2_22 2_96
2_147 2_203
2_223 4_215
2_264 2_324
1_147 1_203
2_370 2_428
3_23 3_88
3_135 3_195
4_23 4_88
4_135 4_195
1_223 3_215
1_229 2_229
1_232 2_232
1_264 1_324
1_370 1_428
Glycosylation Type MAMMALIAN
Glycosylation Link Type Site
N 1_300
N 2_300
Related Record Type Details
TARGET->CONJUGATED TOXIN
TOXIN -> CONJUGATE
Related Record Type Details
METABOLITE ACTIVE -> PARENT
Related Record Type Details
ACTIVE MOIETY
Name Property Type Amount Referenced Substance Defining Parameters References
MOL_WEIGHT:WEIGHT AVERAGE CHEMICAL
Molecular Formula CHEMICAL