| Stereochemistry | ACHIRAL |
| Molecular Formula | C11H17N3O3S |
| Molecular Weight | 271.336 |
| Optical Activity | NONE |
| Defined Stereocenters | 0 / 0 |
| E/Z Centers | 0 |
| Charge | 0 |
SHOW SMILES / InChI
SMILES
CCCCNC(=O)NS(=O)(=O)C1=CC=C(N)C=C1
InChI
InChIKey=VDTNNGKXZGSZIP-UHFFFAOYSA-N
InChI=1S/C11H17N3O3S/c1-2-3-8-13-11(15)14-18(16,17)10-6-4-9(12)5-7-10/h4-7H,2-3,8,12H2,1H3,(H2,13,14,15)
| Molecular Formula | C11H17N3O3S |
| Molecular Weight | 271.336 |
| Charge | 0 |
| Count |
MOL RATIO
1 MOL RATIO (average) |
| Stereochemistry | ACHIRAL |
| Additional Stereochemistry | No |
| Defined Stereocenters | 0 / 0 |
| E/Z Centers | 0 |
| Optical Activity | NONE |
Approval Year
PubMed
Sample Use Guides
Adult under 65 years old: 1 to 2 tablets a day, taken once; the dose is adjusted according to blood glucose.
The person over 65 or weakened: the initial dose is 1/2 tablet daily. Adjustment of the dosage is then made, depending on the blood glucose, in stages of at least 15 days.
Route of Administration:
Oral
It was observed the effect of BZ-55 (carbutamide) on one of the fundamental ways by which glucose is produced by the body. Slices of 60-90 mg weight were taken from the liver of a fed, normal rabbit. These slices were incubated in a phosphate-saline medium, pH 7.5, for 45 minutes, and the amounts of glucose produced by the slices were measured. Various amounts of BZ-55 (0.03; 0.06; 0.12; 0.25; 0.50 mg/ml) were added to the media, and in some cases insulin (1 unit/ml) or glucagon (2.5 y/ml) or insulin and glucagon were also added. Statistical analyses suggested that there was an inhibitory effect of BZ-55 upon glucose production in the absence of added insulin or glucagon.
