U.S. Department of Health & Human Services Divider Arrow National Institutes of Health Divider Arrow NCATS

Details

Stereochemistry ACHIRAL
Molecular Formula C20H21F3N2OS
Molecular Weight 394.454
Optical Activity NONE
Defined Stereocenters 0 / 0
E/Z Centers 0
Charge 0

SHOW SMILES / InChI
Structure of FLUACIZINE

SMILES

CCN(CC)CCC(=O)N1C2=CC(=CC=C2SC3=C1C=CC=C3)C(F)(F)F

InChI

InChIKey=VHEOUJNDDFHPGJ-UHFFFAOYSA-N
InChI=1S/C20H21F3N2OS/c1-3-24(4-2)12-11-19(26)25-15-7-5-6-8-17(15)27-18-10-9-14(13-16(18)25)20(21,22)23/h5-10,13H,3-4,11-12H2,1-2H3

HIDE SMILES / InChI

Molecular Formula C20H21F3N2OS
Molecular Weight 394.454
Charge 0
Count
Stereochemistry ACHIRAL
Additional Stereochemistry No
Defined Stereocenters 0 / 0
E/Z Centers 0
Optical Activity NONE

FLUACIZINE, a member of phenothiazines, is a tricyclic antidepressant developed in Russia. It is the trifluoromethyl analog of chloracizine.

Approval Year

PubMed

PubMed

TitleDatePubMed
Effect of fluacizine on the uptake of exogenous noradrenalin.
1974 Nov
Effect of fluacizine on the uptake of exogenous noradrenalin by the isolated rat vas deferens.
1974 Sep
Patents

Patents

Substance Class Chemical
Created
by admin
on Fri Dec 15 16:24:15 GMT 2023
Edited
by admin
on Fri Dec 15 16:24:15 GMT 2023
Record UNII
E2M3325B1R
Record Status Validated (UNII)
Record Version
  • Download
Name Type Language
FLUACIZINE
INN   MI  
INN  
Official Name English
FLUACIZINE [MI]
Common Name English
fluacizine [INN]
Common Name English
10-(3-(DIETHYLAMINO)PROPIONYL)-2-(TRIFLUOROMETHYL)PHENOTHIAZINE
Systematic Name English
Classification Tree Code System Code
NCI_THESAURUS C29756
Created by admin on Fri Dec 15 16:24:15 GMT 2023 , Edited by admin on Fri Dec 15 16:24:15 GMT 2023
Code System Code Type Description
SMS_ID
100000081022
Created by admin on Fri Dec 15 16:24:15 GMT 2023 , Edited by admin on Fri Dec 15 16:24:15 GMT 2023
PRIMARY
WIKIPEDIA
Fluacizine
Created by admin on Fri Dec 15 16:24:15 GMT 2023 , Edited by admin on Fri Dec 15 16:24:15 GMT 2023
PRIMARY
INN
2999
Created by admin on Fri Dec 15 16:24:15 GMT 2023 , Edited by admin on Fri Dec 15 16:24:15 GMT 2023
PRIMARY
ChEMBL
CHEMBL92281
Created by admin on Fri Dec 15 16:24:15 GMT 2023 , Edited by admin on Fri Dec 15 16:24:15 GMT 2023
PRIMARY
PUBCHEM
161562
Created by admin on Fri Dec 15 16:24:15 GMT 2023 , Edited by admin on Fri Dec 15 16:24:15 GMT 2023
PRIMARY
FDA UNII
E2M3325B1R
Created by admin on Fri Dec 15 16:24:15 GMT 2023 , Edited by admin on Fri Dec 15 16:24:15 GMT 2023
PRIMARY
NCI_THESAURUS
C65702
Created by admin on Fri Dec 15 16:24:15 GMT 2023 , Edited by admin on Fri Dec 15 16:24:15 GMT 2023
PRIMARY
EPA CompTox
DTXSID2046175
Created by admin on Fri Dec 15 16:24:15 GMT 2023 , Edited by admin on Fri Dec 15 16:24:15 GMT 2023
PRIMARY
CAS
30223-48-4
Created by admin on Fri Dec 15 16:24:15 GMT 2023 , Edited by admin on Fri Dec 15 16:24:15 GMT 2023
PRIMARY
EVMPD
SUB07660MIG
Created by admin on Fri Dec 15 16:24:15 GMT 2023 , Edited by admin on Fri Dec 15 16:24:15 GMT 2023
PRIMARY
MERCK INDEX
m5415
Created by admin on Fri Dec 15 16:24:15 GMT 2023 , Edited by admin on Fri Dec 15 16:24:15 GMT 2023
PRIMARY Merck Index
DRUG CENTRAL
3230
Created by admin on Fri Dec 15 16:24:15 GMT 2023 , Edited by admin on Fri Dec 15 16:24:15 GMT 2023
PRIMARY
Related Record Type Details
ACTIVE MOIETY