FLUACIZINE

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National Institutes of Health Divider Arrow

NCATS

Details

Stereochemistry	ACHIRAL
Molecular Formula	C20H21F3N2OS
Molecular Weight	394.454
Optical Activity	NONE
Defined Stereocenters	0 / 0
E/Z Centers	0
Charge	0

SHOW SMILES / InChI

Structure of FLUACIZINE

Structure Search

SMILES

CCN(CC)CCC(=O)N1C2=CC(=CC=C2SC3=C1C=CC=C3)C(F)(F)F

InChI

InChIKey=VHEOUJNDDFHPGJ-UHFFFAOYSA-N

InChI=1S/C20H21F3N2OS/c1-3-24(4-2)12-11-19(26)25-15-7-5-6-8-17(15)27-18-10-9-14(13-16(18)25)20(21,22)23/h5-10,13H,3-4,11-12H2,1-2H3

HIDE SMILES / InChI

Molecular Formula	C20H21F3N2OS
Molecular Weight	394.454
Charge	0
Count

Stereochemistry	ACHIRAL
Additional Stereochemistry	No
Defined Stereocenters	0 / 0
E/Z Centers	0
Optical Activity	NONE

Description
Sources: https://www.ncbi.nlm.nih.gov/mesh/67001228 | https://www.ncbi.nlm.nih.gov/pubmed/6305

FLUACIZINE, a member of phenothiazines, is a tricyclic antidepressant developed in Russia. It is the trifluoromethyl analog of chloracizine.

Approval Year

PubMed

PubMed

Title	Date	PubMed
Effect of fluacizine on the uptake of exogenous noradrenalin.	1974 Nov	4441683
Effect of fluacizine on the uptake of exogenous noradrenalin by the isolated rat vas deferens.	1974 Sep	4153328

Patents

Patents

Substance Class	Chemical Created by `admin` on `Fri Dec 15 16:24:15 UTC 2023` Edited by `admin` on `Fri Dec 15 16:24:15 UTC 2023`
Record UNII	E2M3325B1R
Record Status	`Validated (UNII)`
Record Version

Download

Name

Type

Language

FLUACIZINE

Official Name

English

FLUACIZINE [MI]

Common Name

English

fluacizine [INN]

Common Name

English

10-(3-(DIETHYLAMINO)PROPIONYL)-2-(TRIFLUOROMETHYL)PHENOTHIAZINE

Systematic Name

English

Classification Tree Code System Code

NCI_THESAURUS

C29756

Created by admin on Fri Dec 15 16:24:15 UTC 2023 , Edited by admin on Fri Dec 15 16:24:15 UTC 2023

Code System Code Type Description

SMS_ID

100000081022

Created by admin on Fri Dec 15 16:24:15 UTC 2023 , Edited by admin on Fri Dec 15 16:24:15 UTC 2023

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WIKIPEDIA

Fluacizine

Created by admin on Fri Dec 15 16:24:15 UTC 2023 , Edited by admin on Fri Dec 15 16:24:15 UTC 2023

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INN

2999

Created by admin on Fri Dec 15 16:24:15 UTC 2023 , Edited by admin on Fri Dec 15 16:24:15 UTC 2023

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ChEMBL

CHEMBL92281

Created by admin on Fri Dec 15 16:24:15 UTC 2023 , Edited by admin on Fri Dec 15 16:24:15 UTC 2023

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PUBCHEM

161562

Created by admin on Fri Dec 15 16:24:15 UTC 2023 , Edited by admin on Fri Dec 15 16:24:15 UTC 2023

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FDA UNII

E2M3325B1R

Created by admin on Fri Dec 15 16:24:15 UTC 2023 , Edited by admin on Fri Dec 15 16:24:15 UTC 2023

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NCI_THESAURUS

C65702

Created by admin on Fri Dec 15 16:24:15 UTC 2023 , Edited by admin on Fri Dec 15 16:24:15 UTC 2023

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EPA CompTox

DTXSID2046175

Created by admin on Fri Dec 15 16:24:15 UTC 2023 , Edited by admin on Fri Dec 15 16:24:15 UTC 2023

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CAS

30223-48-4

Created by admin on Fri Dec 15 16:24:15 UTC 2023 , Edited by admin on Fri Dec 15 16:24:15 UTC 2023

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EVMPD

SUB07660MIG

Created by admin on Fri Dec 15 16:24:15 UTC 2023 , Edited by admin on Fri Dec 15 16:24:15 UTC 2023

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MERCK INDEX

m5415

Created by admin on Fri Dec 15 16:24:15 UTC 2023 , Edited by admin on Fri Dec 15 16:24:15 UTC 2023

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Merck Index

DRUG CENTRAL

3230

Created by admin on Fri Dec 15 16:24:15 UTC 2023 , Edited by admin on Fri Dec 15 16:24:15 UTC 2023

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Related Record Type Details


					E2M3325B1R

ACTIVE MOIETY