FLUACIZINE

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National Institutes of Health Divider Arrow

NCATS

Details

Stereochemistry	ACHIRAL
Molecular Formula	C20H21F3N2OS
Molecular Weight	394.454
Optical Activity	NONE
Defined Stereocenters	0 / 0
E/Z Centers	0
Charge	0

SHOW SMILES / InChI

Structure of FLUACIZINE

Structure Search

SMILES

CCN(CC)CCC(=O)N1C2=CC(=CC=C2SC3=C1C=CC=C3)C(F)(F)F

InChI

InChIKey=VHEOUJNDDFHPGJ-UHFFFAOYSA-N

InChI=1S/C20H21F3N2OS/c1-3-24(4-2)12-11-19(26)25-15-7-5-6-8-17(15)27-18-10-9-14(13-16(18)25)20(21,22)23/h5-10,13H,3-4,11-12H2,1-2H3

HIDE SMILES / InChI

Molecular Formula	C20H21F3N2OS
Molecular Weight	394.454
Charge	0
Count

Stereochemistry	ACHIRAL
Additional Stereochemistry	No
Defined Stereocenters	0 / 0
E/Z Centers	0
Optical Activity	NONE

Description
Sources: https://www.ncbi.nlm.nih.gov/mesh/67001228 | https://www.ncbi.nlm.nih.gov/pubmed/6305

FLUACIZINE, a member of phenothiazines, is a tricyclic antidepressant developed in Russia. It is the trifluoromethyl analog of chloracizine.

Approval Year

PubMed

PubMed

Title	Date	PubMed
Effect of fluacizine on the uptake of exogenous noradrenalin.	1974-11	4441683
Effect of fluacizine on the uptake of exogenous noradrenalin by the isolated rat vas deferens.	1974-09	4153328

Patents

Patents

Substance Class	Chemical Created by `admin` on `Mon Mar 31 18:26:56 GMT 2025` Edited by `admin` on `Mon Mar 31 18:26:56 GMT 2025`
Record UNII	E2M3325B1R
Record Status	`Validated (UNII)`
Record Version

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Name

Type

Language

FLUACIZINE [MI]

Preferred Name

English

FLUACIZINE

Official Name

English

fluacizine [INN]

Common Name

English

10-(3-(DIETHYLAMINO)PROPIONYL)-2-(TRIFLUOROMETHYL)PHENOTHIAZINE

Systematic Name

English

Classification Tree Code System Code

NCI_THESAURUS

C29756

Created by admin on Mon Mar 31 18:26:56 GMT 2025 , Edited by admin on Mon Mar 31 18:26:56 GMT 2025

Code System Code Type Description

SMS_ID

100000081022

Created by admin on Mon Mar 31 18:26:56 GMT 2025 , Edited by admin on Mon Mar 31 18:26:56 GMT 2025

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WIKIPEDIA

Fluacizine

Created by admin on Mon Mar 31 18:26:56 GMT 2025 , Edited by admin on Mon Mar 31 18:26:56 GMT 2025

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INN

2999

Created by admin on Mon Mar 31 18:26:56 GMT 2025 , Edited by admin on Mon Mar 31 18:26:56 GMT 2025

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ChEMBL

CHEMBL92281

Created by admin on Mon Mar 31 18:26:56 GMT 2025 , Edited by admin on Mon Mar 31 18:26:56 GMT 2025

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PUBCHEM

161562

Created by admin on Mon Mar 31 18:26:56 GMT 2025 , Edited by admin on Mon Mar 31 18:26:56 GMT 2025

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FDA UNII

E2M3325B1R

Created by admin on Mon Mar 31 18:26:56 GMT 2025 , Edited by admin on Mon Mar 31 18:26:56 GMT 2025

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NCI_THESAURUS

C65702

Created by admin on Mon Mar 31 18:26:56 GMT 2025 , Edited by admin on Mon Mar 31 18:26:56 GMT 2025

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EPA CompTox

DTXSID2046175

Created by admin on Mon Mar 31 18:26:56 GMT 2025 , Edited by admin on Mon Mar 31 18:26:56 GMT 2025

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CAS

30223-48-4

Created by admin on Mon Mar 31 18:26:56 GMT 2025 , Edited by admin on Mon Mar 31 18:26:56 GMT 2025

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EVMPD

SUB07660MIG

Created by admin on Mon Mar 31 18:26:56 GMT 2025 , Edited by admin on Mon Mar 31 18:26:56 GMT 2025

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MERCK INDEX

m5415

Created by admin on Mon Mar 31 18:26:56 GMT 2025 , Edited by admin on Mon Mar 31 18:26:56 GMT 2025

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Merck Index

DRUG CENTRAL

3230

Created by admin on Mon Mar 31 18:26:56 GMT 2025 , Edited by admin on Mon Mar 31 18:26:56 GMT 2025

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Related Record Type Details


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