DAROVASERTIB

Details

Stereochemistry	ACHIRAL
Molecular Formula	C22H23F3N8O
Molecular Weight	472.4662
Optical Activity	NONE
Defined Stereocenters	0 / 0
E/Z Centers	0
Charge	0

SHOW SMILES / InChI

Structure Search

SMILES

CC1(N)CCN(CC1)C2=CC=CN=C2NC(=O)C3=C(N)N=CC(=N3)C4=C(C=CC=N4)C(F)(F)F

InChI

InChIKey=XXJXHXJWQSCNPX-UHFFFAOYSA-N

InChI=1S/C22H23F3N8O/c1-21(27)6-10-33(11-7-21)15-5-3-9-29-19(15)32-20(34)17-18(26)30-12-14(31-17)16-13(22(23,24)25)4-2-8-28-16/h2-5,8-9,12H,6-7,10-11,27H2,1H3,(H2,26,30)(H,29,32,34)

HIDE SMILES / InChI

Molecular Formula	C22H23F3N8O
Molecular Weight	472.4662
Charge	0
Count

Stereochemistry	ACHIRAL
Additional Stereochemistry	No
Defined Stereocenters	0 / 0
E/Z Centers	0
Optical Activity	NONE

Approval Year

Targets

Primary Target	Pharmacology	Condition	Potency
Protein kinase C, PKC; classical/novel 4 Target ID: CHEMBL2096620 Sources: https://worldwide.espacenet.com/publicationDetails/biblio?DB=EPODOC&II=0&ND=3&adjacent=true&locale=en_EP&FT=D&date=20160211&CC=WO&NR=2016020864A1&KC=A1	Inhibitor 8297

Substance Class	Chemical Created by `admin` on `Sat Dec 16 10:17:57 UTC 2023` Edited by `admin` on `Sat Dec 16 10:17:57 UTC 2023`
Record UNII	E0YF0M8O09
Record Status	`Validated (UNII)`
Record Version

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Name

Type

Language

DAROVASERTIB

Official Name

English

3-AMINO-N-(3-(4-AMINO-4-METHYLPIPERIDIN-1-YL)PYRIDIN-2-YL)-6-(3-(TRIFLUOROMETHYL)PYRIDIN-2-YL)PYRAZINE-2-CARBOXAMIDE

Systematic Name

English

2-PYRAZINECARBOXAMIDE, 3-AMINO-N-(3-(4-AMINO-4-METHYL-1-PIPERIDINYL)-2-PYRIDINYL)-6-(3-(TRIFLUOROMETHYL)-2-PYRIDINYL)-

Systematic Name

English

LXS196

Code

English

Darovasertib [WHO-DD]

Common Name

English

IDE-196

Code

English

IDE196

Code

English

LXS-196

Code

English

DAROVASERTIB [USAN]

Common Name

English

NVP-LXS-196

Code

English

darovasertib [INN]

Common Name

English

Classification Tree Code System Code

FDA ORPHAN DRUG

873322