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Details

Stereochemistry ACHIRAL
Molecular Formula C20H12F2N6
Molecular Weight 374.3463
Optical Activity NONE
Defined Stereocenters 0 / 0
E/Z Centers 0
Charge 0

SHOW SMILES / InChI
Structure of JNJ-38877618

SMILES

FC(F)(C1=NN=C2C=CC(=NN12)C3=CC=NC=C3)C4=CC5=C(C=C4)N=CC=C5

InChI

InChIKey=KOAWAWHSMVKCON-UHFFFAOYSA-N
InChI=1S/C20H12F2N6/c21-20(22,15-3-4-16-14(12-15)2-1-9-24-16)19-26-25-18-6-5-17(27-28(18)19)13-7-10-23-11-8-13/h1-12H

HIDE SMILES / InChI

Molecular Formula C20H12F2N6
Molecular Weight 374.3463
Charge 0
Count
Stereochemistry ACHIRAL
Additional Stereochemistry No
Defined Stereocenters 0 / 0
E/Z Centers 0
Optical Activity NONE

Approval Year

Substance Class Chemical
Created
by admin
on Sat Dec 16 11:54:47 GMT 2023
Edited
by admin
on Sat Dec 16 11:54:47 GMT 2023
Record UNII
E0B2IZB5H5
Record Status Validated (UNII)
Record Version
  • Download
Name Type Language
JNJ-38877618
Code English
OMO-1
Code English
OMO1
Code English
6-(DIFLUORO-(6-(4-PYRIDYL)-(1,2,4)TRIAZOLO(4,3-B)PYRIDAZIN-3-YL)METHYL)QUINOLINE
Systematic Name English
QUINOLINE, 6-(DIFLUORO(6-(4-PYRIDINYL)-1,2,4-TRIAZOLO(4,3-B)PYRIDAZIN-3-YL)METHYL)-
Systematic Name English
OMO 1 [WHO-DD]
Common Name English
JNJ38877618
Code English
Code System Code Type Description
CAS
943540-74-7
Created by admin on Sat Dec 16 11:54:47 GMT 2023 , Edited by admin on Sat Dec 16 11:54:47 GMT 2023
PRIMARY
FDA UNII
E0B2IZB5H5
Created by admin on Sat Dec 16 11:54:47 GMT 2023 , Edited by admin on Sat Dec 16 11:54:47 GMT 2023
PRIMARY
PUBCHEM
57654476
Created by admin on Sat Dec 16 11:54:47 GMT 2023 , Edited by admin on Sat Dec 16 11:54:47 GMT 2023
PRIMARY
SMS_ID
300000042483
Created by admin on Sat Dec 16 11:54:47 GMT 2023 , Edited by admin on Sat Dec 16 11:54:47 GMT 2023
PRIMARY
Related Record Type Details
ACTIVE MOIETY
Originator: Janssen-Cilag; Mechanism of Action: Proto oncogene protein c met inhibitor; Orphan Drug Status: No; On Fast track: No; New Molecular Entity: Yes; Highest Development Phase: Phase I for Cancer; Most Recent Event: 15 Oct 2013 Janssen-Cilag plans a phase I trial for Healthy volunteers in the UK (NCT01964872)