JNJ-38877618

FC(F)(C1=NN=C2C=CC(=NN12)C3=CC=NC=C3)C4=CC5=C(C=C4)N=CC=C5

InChIKey=KOAWAWHSMVKCON-UHFFFAOYSA-N

InChI=1S/C20H12F2N6/c21-20(22,15-3-4-16-14(12-15)2-1-9-24-16)19-26-25-18-6-5-17(27-28(18)19)13-7-10-23-11-8-13/h1-12H

Stereochemistry	ACHIRAL
Additional Stereochemistry	No
Defined Stereocenters	0 / 0
E/Z Centers	0
Optical Activity	NONE

C_max

Value	Dose	Co-administered	Analyte	Population
1372 ng/mL EXPERIMENT https://pubmed.ncbi.nlm.nih.gov/37260332/	250 mg 2 times / day multiple, oral dose: 250 mg route of administration: Oral experiment type: MULTIPLE co-administered:		JNJ-38877618 plasma	Homo sapiens population: UNHEALTHY age: ADULT sex: FEMALE / MALE food status: UNKNOWN

AUC

Value	Dose	Co-administered	Analyte	Population
5684 ng × h/mL EXPERIMENT https://pubmed.ncbi.nlm.nih.gov/37260332/	250 mg 2 times / day multiple, oral dose: 250 mg route of administration: Oral experiment type: MULTIPLE co-administered:		JNJ-38877618 plasma	Homo sapiens population: UNHEALTHY age: ADULT sex: FEMALE / MALE food status: UNKNOWN

T_1/2

Value	Dose	Co-administered	Analyte	Population
2.75 h EXPERIMENT https://pubmed.ncbi.nlm.nih.gov/37260332/	250 mg 2 times / day multiple, oral dose: 250 mg route of administration: Oral experiment type: MULTIPLE co-administered:		JNJ-38877618 plasma	Homo sapiens population: UNHEALTHY age: ADULT sex: FEMALE / MALE food status: UNKNOWN

Substance Class	Chemical Created by `admin` on `Tue Apr 01 17:24:47 GMT 2025` Edited by `admin` on `Tue Apr 01 17:24:47 GMT 2025`
Record UNII	E0B2IZB5H5
Record Status	`Validated (UNII)`
Record Version

Name

Type

Language

JNJ-38877618

Code

English

JNJ38877618

Preferred Name

English

OMO-1

Code

English

OMO1

Code

English

6-(DIFLUORO-(6-(4-PYRIDYL)-(1,2,4)TRIAZOLO(4,3-B)PYRIDAZIN-3-YL)METHYL)QUINOLINE

Systematic Name

English

QUINOLINE, 6-(DIFLUORO(6-(4-PYRIDINYL)-1,2,4-TRIAZOLO(4,3-B)PYRIDAZIN-3-YL)METHYL)-

Systematic Name

English

OMO 1 [WHO-DD]

Common Name

English

Code System Code Type Description

CAS

943540-74-7