Details
| Stereochemistry | RACEMIC |
| Molecular Formula | C21H27NO.ClH |
| Molecular Weight | 345.906 |
| Optical Activity | ( + / - ) |
| Defined Stereocenters | 0 / 1 |
| E/Z Centers | 0 |
| Charge | 0 |
SHOW SMILES / InChI
SMILES
Cl.CC(CC(O)(C1=CC=CC=C1)C2=CC=CC=C2)N3CCCCC3
InChI
InChIKey=YFROVFWOPWMFRE-UHFFFAOYSA-N
InChI=1S/C21H27NO.ClH/c1-18(22-15-9-4-10-16-22)17-21(23,19-11-5-2-6-12-19)20-13-7-3-8-14-20;/h2-3,5-8,11-14,18,23H,4,9-10,15-17H2,1H3;1H
| Molecular Formula | C21H27NO |
| Molecular Weight | 309.4452 |
| Charge | 0 |
| Count |
|
| Stereochemistry | RACEMIC |
| Additional Stereochemistry | No |
| Defined Stereocenters | 0 / 1 |
| E/Z Centers | 0 |
| Optical Activity | ( + / - ) |
| Molecular Formula | ClH |
| Molecular Weight | 36.461 |
| Charge | 0 |
| Count |
|
| Stereochemistry | ACHIRAL |
| Additional Stereochemistry | No |
| Defined Stereocenters | 0 / 0 |
| E/Z Centers | 0 |
| Optical Activity | NONE |
Aspaminol (1,1 diphenyl-3-piperidinobutanol hydrochloride) is a nonspecific smooth muscle relaxant. It inhibits calcium uptake. The relaxation of smooth muscle induced by aspaminol may be due to a combining of aspaminol with calcium ions at the binding sites on the surface of smooth muscle, thus decreasing the supply of calcium ions to the contractile element.
Approval Year
PubMed
| Title | Date | PubMed |
|---|---|---|
| Relationship between synaptosomal calcium uptake and antinociceptive action of morphine. | 1983-06 |
|
| Effect of 1,1-diphenyl-3-piperidinobutanol hydrochloride (Aspaminol) on the stimuli-induced calcium uptake in rat brain synaptosomes. | 1981-12 |
|
| Comparison of effects of external Ca2+ on antioxytocin actions of antispasmodics in ovariectomized and estradiol-treated rat uteri. | 1980-08 |
|
| Calcium ions and relaxation of intestinal smooth muscle induced by papaverine and aspaminol. | 1977-04 |
| Substance Class |
Chemical
Created
by
admin
on
Edited
Mon Mar 31 21:22:40 GMT 2025
by
admin
on
Mon Mar 31 21:22:40 GMT 2025
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| Record UNII |
E071P1I925
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| Record Status |
Validated (UNII)
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| Record Version |
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55701-20-7
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admin on Mon Mar 31 21:22:40 GMT 2025 , Edited by admin on Mon Mar 31 21:22:40 GMT 2025
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E071P1I925
Created by
admin on Mon Mar 31 21:22:40 GMT 2025 , Edited by admin on Mon Mar 31 21:22:40 GMT 2025
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PARENT -> SALT/SOLVATE |
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ACTIVE MOIETY |