Enozertinib

Approval Year

Substance Class	Concept
Record UNII	DU24UP8R94
Record Status	`Validated (UNII)`
Record Version

Download

Name

Type

Language

enozertinib [INN]

Preferred Name

English

Enozertinib

Official Name

English

N-[2-[4-(4-Cyclopropyl-1-piperazinyl)-1-piperidinyl]-5-[[6-[(3R)-3-(3,5-difluorophenyl)-2-isoxazolidinyl]-4-pyrimidinyl]amino]-4-methoxyphenyl]-2-propenamide

Systematic Name

English

Code System Code Type Description

PUBCHEM

155696192

Created by admin on Wed Apr 02 10:18:07 GMT 2025 , Edited by admin on Wed Apr 02 10:18:07 GMT 2025

PRIMARY

FDA UNII

DU24UP8R94

Created by admin on Wed Apr 02 10:18:07 GMT 2025 , Edited by admin on Wed Apr 02 10:18:07 GMT 2025

PRIMARY

INN

13344

Created by admin on Wed Apr 02 10:18:07 GMT 2025 , Edited by admin on Wed Apr 02 10:18:07 GMT 2025

PRIMARY

CAS

2489185-38-6

Created by admin on Wed Apr 02 10:18:07 GMT 2025 , Edited by admin on Wed Apr 02 10:18:07 GMT 2025

PRIMARY

This is a non-substance concept

Related Record Type Details


					DU24UP8R94

Enozertinib

ACTIVE MOIETY

Comments:

epidermal growth factor receptor tyrosine kinase inhibitor, antineoplastic. target EGFR and HER2 alterations (EGFR exon 20 insertion, EGFR exon 20 insertion mutant requires a cysteine residue in the active site for covalent binding, FR and HER2 exon 20 insertion mutant cell,

Interaction Type:

PRECLINICAL

Amount: