Details
Stereochemistry | ACHIRAL |
Molecular Formula | C2H2F4 |
Molecular Weight | 102.0309 |
Optical Activity | NONE |
Defined Stereocenters | 0 / 0 |
E/Z Centers | 0 |
Charge | 0 |
SHOW SMILES / InChI
SMILES
FCC(F)(F)F
InChI
InChIKey=LVGUZGTVOIAKKC-UHFFFAOYSA-N
InChI=1S/C2H2F4/c3-1-2(4,5)6/h1H2
Molecular Formula | C2H2F4 |
Molecular Weight | 102.0309 |
Charge | 0 |
Count |
|
Stereochemistry | ACHIRAL |
Additional Stereochemistry | No |
Defined Stereocenters | 0 / 0 |
E/Z Centers | 0 |
Optical Activity | NONE |
Norflurane (1,1,1,2-Tetrafluoroethane) is a non-flammable gas used primarily as a "high-temperature" refrigerant for domestic refrigeration and automobile air conditioners. Other uses include plastic foam blowing, as a cleaning solvent, a propellant for the delivery of pharmaceuticals (e.g. bronchodilators), wine cork removers, gas dusters, and in air driers for removing the moisture from compressed air. Liquid Norflurane absorbs a high amount of thermal energy from the environment during its evaporation at atmospheric pressure. Norflurane is commercially available as a liquid in pressurized cylinders or cans. Norflurane is used as a propellant for some metered dose inhalers and as an inhalational anesthetic agent in animal studies.
Approval Year
PubMed
Title | Date | PubMed |
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Medical aerosol propellant interference with infrared anaesthetic gas monitors. | 2004 Jun |
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CH-stretching overtone spectroscopy of 1,1,1,2-tetrafluoroethane. | 2005 Jun 23 |
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Orofacial cold hyperalgesia due to infraorbital nerve constriction injury in rats: reversal by endothelin receptor antagonists but not non-steroidal anti-inflammatory drugs. | 2006 Jul |
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Toxicokinetics of 1,1,1,2-tetrafluoroethane (HFC-134a) in male volunteers after experimental exposure. | 2006 Nov 1 |
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Extrinsic allergic alveolitis with eosinophil infiltration induced by 1,1,1,2-tetrafluoroethane (HFC-134a): a case report. | 2007 |
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Cryosurgical treatment of gingival melanin pigmentation with tetrafluoroethane. | 2007 Apr |
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Dynamic skin cooling with an environmentally compatible alternative cryogen during laser surgery. | 2007 Dec |
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Stability and activity of lipase in subcritical 1,1,1,2-tetrafluoroethane (R134a). | 2007 Dec |
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Determination of reference ultrasound parameters for model and hydrofluoroalkane propellants using high-resolution ultrasonic spectroscopy. | 2008 |
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Dental pulp testing: a review. | 2009 |
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A force field for 3,3,3-fluoro-1-propenes, including HFO-1234yf. | 2010 Aug 12 |
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Effect of repeated refrigerant spray applications using various carriers on pulpal temperature change. | 2010 May-Jun |
|
Symmetry measures of the electron density. | 2010 Oct |
Patents
Substance Class |
Chemical
Created
by
admin
on
Edited
Fri Dec 15 15:19:32 UTC 2023
by
admin
on
Fri Dec 15 15:19:32 UTC 2023
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Record UNII |
DH9E53K1Y8
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Record Status |
Validated (UNII)
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Record Version |
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EPA PESTICIDE CODE |
100895
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DTXSID1021324
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1,1,1,2-Tetrafluoroethane
Created by
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PRIMARY | 1,1,1,2-tetrafluoroethane, R-134a, Forane 134a, Genetron 134a, Florasol 134a, Suva 134a or HFC-134a, also known as norflurane (INN), is a haloalkane refrigerant with thermodynamic properties similar to R-12 (dichlorodifluoromethane) but with insignificant ozone depletion potential. It has the formula CH2FCF3 and a boiling point of −26.3 ?C (−15.34 ?F) at atmospheric pressure. R-134a cylinders are colored light blue.[2] Attempts at phasing out its use as a refrigerant with substances that have lower global warming potentials, such as HFO-1234yf are underway. |
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ACTIVE MOIETY |