Details
| Stereochemistry | ABSOLUTE |
| Molecular Formula | 2C20H27NO2.C4H6O6 |
| Molecular Weight | 776.9546 |
| Optical Activity | UNSPECIFIED |
| Defined Stereocenters | 8 / 8 |
| E/Z Centers | 0 |
| Charge | 0 |
SHOW SMILES / InChI
SMILES
O[C@H]([C@@H](O)C(O)=O)C(O)=O.OC1=CC2=C(C[C@H]3N(CC4CC4)CC[C@@]25CCCC[C@@]35O)C=C1.OC6=CC7=C(C[C@H]8N(CC9CC9)CC[C@@]7%10CCCC[C@@]8%10O)C=C6
InChI
InChIKey=ONHZWTYSVRYZMM-HQLXQQFBSA-N
InChI=1S/2C20H27NO2.C4H6O6/c2*22-16-6-5-15-11-18-20(23)8-2-1-7-19(20,17(15)12-16)9-10-21(18)13-14-3-4-14;5-1(3(7)8)2(6)4(9)10/h2*5-6,12,14,18,22-23H,1-4,7-11,13H2;1-2,5-6H,(H,7,8)(H,9,10)/t2*18-,19+,20-;1-,2-/m111/s1
| Molecular Formula | C20H27NO2 |
| Molecular Weight | 313.4339 |
| Charge | 0 |
| Count |
|
| Stereochemistry | ABSOLUTE |
| Additional Stereochemistry | No |
| Defined Stereocenters | 3 / 3 |
| E/Z Centers | 0 |
| Optical Activity | UNSPECIFIED |
| Molecular Formula | C4H6O6 |
| Molecular Weight | 150.0868 |
| Charge | 0 |
| Count |
|
| Stereochemistry | ABSOLUTE |
| Additional Stereochemistry | No |
| Defined Stereocenters | 2 / 2 |
| E/Z Centers | 0 |
| Optical Activity | UNSPECIFIED |
Oxilorphan (also known as levo-BC-2605) was developed as a long-acting, narcotic antagonist that has agonist properties. Oxilorphan is a partial agonist at the kappa-opioid receptor and antagonist of the mu-opioid receptor. During clinical trials, oxilorphan had led to dysphoria, which combined with its hallucinogenic effects, serves to limit its clinical usefulness. As a result, many patients who experienced these side effects refused to take additional doses in clinical trials.
Approval Year
| Substance Class |
Chemical
Created
by
admin
on
Edited
Fri Dec 15 15:24:12 UTC 2023
by
admin
on
Fri Dec 15 15:24:12 UTC 2023
|
| Record UNII |
D9S0U9ELR7
|
| Record Status |
Validated (UNII)
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| Record Version |
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-
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133083128
Created by
admin on Fri Dec 15 15:24:12 UTC 2023 , Edited by admin on Fri Dec 15 15:24:12 UTC 2023
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PRIMARY | |||
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D9S0U9ELR7
Created by
admin on Fri Dec 15 15:24:12 UTC 2023 , Edited by admin on Fri Dec 15 15:24:12 UTC 2023
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39695-17-5
Created by
admin on Fri Dec 15 15:24:12 UTC 2023 , Edited by admin on Fri Dec 15 15:24:12 UTC 2023
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PRIMARY |
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PARENT -> SALT/SOLVATE | |||
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PARENT -> SALT/SOLVATE |
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ACTIVE MOIETY |