INSULIN ASPART

Description
Sources: https://www.accessdata.fda.gov/drugsatfda_docs/label/2000/20986lbl.pdf | http://endocrine-system.emedtv.com/insulin-aspart/what-is-insulin-aspart-used-for-p3.html

Insulin aspart, a human insulin analogue, is a rapid-acting, parenteral blood glucose-lowering agent. Insulin aspart was marketed under the brand name NovoLog for the treatment of adult patients with diabetes mellitus, for the control of hyperglycemia. The primary activity of the drug is the regulation of glucose metabolism. Insulin aspart binds to the insulin receptors on muscle and fat cells and lower blood glucose by facilitating the cellular uptake of glucose and simultaneously inhibiting the output of glucose from the liver. This drug has an off-label treatment for gestational diabetes (temporary diabetes caused by diabetes).

Approval Year

Targets

Primary Target	Pharmacology	Condition	Potency
Insulin receptor 13 Target ID: P06213 Gene ID: 3643.0 Gene Symbol: INSR Target Organism: Homo sapiens (Human) Sources: https://www.ncbi.nlm.nih.gov/pubmed/17026485 \| https://www.accessdata.fda.gov/drugsatfda_docs/label/2000/20986lbl.pdf	Agonist 2752

Conditions

Condition	Modality	Targets	Highest Phase	Product
diabetes mellitus 3 Sources: https://www.accessdata.fda.gov/drugsatfda_docs/label/2000/20986lbl.pdf	Primary		Approved 8583	NOVOLOG Approved Use NovoLog™ is indicated for the treatment of adult patients with diabetes mellitus, for the control of hyperglycemia. Because NovoLog™ has a more rapid onset and a shorter duration of action than human regular insulin, NovoLog™ should normally be used in regimens together with an intermediate or long-acting insulin. Launch Date 2000

PubMed

Title	Date	PubMed
Efficacy of biphasic insulin aspart in patients with type 2 diabetes.	2005	16519038

Sample Use Guides

In Vivo Use Guide

NovoLog™ (insulin aspart) should be administered by subcutaneous injection in the abdominal wall, the thigh, or the upper arm. Injection sites should be rotated within the same region. As with all insulins, the duration NovoLog™ should generally be given immediately before a meal. The dosage of NovoLog™ should be individualized and determined, based on the physician's advice, in accordance with the needs of the patient. The total daily individual insulin requirement is usually between 0.5 - 1.0 units/kg/day.

Route of Administration: Other

Substance Class	Protein Created by `admin` on `Tue Apr 01 16:22:53 GMT 2025` Edited by `admin` on `Tue Apr 01 16:22:53 GMT 2025`
Protein Sub Type
Sequence Type	COMPLETE
Record UNII	D933668QVX
Record Status	`Validated (UNII)`
Record Version

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Related Record	Type

Name

Type

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INSULIN ASPART

Official Name

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NOVOLOG

Preferred Name

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INA-X14

Code

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Insulin aspart protamine [WHO-DD]

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INSULIN ASPART [USAN]

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INSULIN ASPART [JAN]

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INSULIN ASPART [MI]

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insulin aspart [INN]

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INSULIN ASPART RECOMBINANT [ORANGE BOOK]

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RYZODEG 70/30 COMPONENT INSULIN ASPART

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INSULIN, ASPART, HUMAN

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INSULIN, ASPART PROTAMINE, HUMAN

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INSULIN ASPART [USP-RS]

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INSULIN ASPART [EMA EPAR]

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NN-1218

Code

English

B-28-ASP-INSULIN

Code

English

INSULIN-X14

Code

English

INSULIN ASPART PROTAMINE RECOMBINANT [ORANGE BOOK]

Common Name

English

NOVORAPID

Brand Name

English

NN1218

Code

English

ASPART-PH20

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English

B28-ASP-INSULIN

Code

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Insulin aspart protamine (crystalline) [WHO-DD]

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INSULIN B28(ASP) PROTAMINE RECOMBINANT HUMAN

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INSULIN,ASPART PROTAMINE [VANDF]

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INSULIN X14

Code

English

INSULIN ASPART [EP MONOGRAPH]

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Classification Tree Code System Code

NDF-RT

N0000004931