Details
| Stereochemistry | ABSOLUTE |
| Molecular Formula | C10H11NO4 |
| Molecular Weight | 209.1986 |
| Optical Activity | UNSPECIFIED |
| Defined Stereocenters | 1 / 1 |
| E/Z Centers | 0 |
| Charge | 0 |
SHOW SMILES / InChI
SMILES
CC1=C(C=CC(=C1)C(O)=O)[C@H](N)C(O)=O
InChI
InChIKey=SGIKDIUCJAUSRD-QMMMGPOBSA-N
InChI=1S/C10H11NO4/c1-5-4-6(9(12)13)2-3-7(5)8(11)10(14)15/h2-4,8H,11H2,1H3,(H,12,13)(H,14,15)/t8-/m0/s1
| Molecular Formula | C10H11NO4 |
| Molecular Weight | 209.1986 |
| Charge | 0 |
| Count |
|
| Stereochemistry | ABSOLUTE |
| Additional Stereochemistry | No |
| Defined Stereocenters | 1 / 1 |
| E/Z Centers | 0 |
| Optical Activity | UNSPECIFIED |
Approval Year
PubMed
| Title | Date | PubMed |
|---|---|---|
| Competitive antagonism at metabotropic glutamate receptors by (S)-4-carboxyphenylglycine and (RS)-alpha-methyl-4-carboxyphenylglycine. | 1993 Jan 15 |
|
| Reduction of sensory and metabotropic glutamate receptor responses in the thalamus by the novel metabotropic glutamate receptor-1-selective antagonist S-2-methyl-4-carboxy-phenylglycine. | 1998 Aug |
|
| Neuroprotective activity of the potent and selective mGlu1a metabotropic glutamate receptor antagonist, (+)-2-methyl-4 carboxyphenylglycine (LY367385): comparison with LY357366, a broader spectrum antagonist with equal affinity for mGlu1a and mGlu5 receptors. | 1999 Feb |
|
| Anticonvulsant actions of LY 367385 ((+)-2-methyl-4-carboxyphenylglycine) and AIDA ((RS)-1-aminoindan-1,5-dicarboxylic acid). | 1999 Feb 26 |
|
| mGluR1 antagonist decreases tyrosine phosphorylation of NMDA receptor and attenuates infarct size after transient focal cerebral ischemia. | 2008 Jun |
Patents
| Substance Class |
Chemical
Created
by
admin
on
Edited
Sat Dec 16 10:01:30 GMT 2023
by
admin
on
Sat Dec 16 10:01:30 GMT 2023
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| Record UNII |
D8UW47H17B
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| Record Status |
Validated (UNII)
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| Record Version |
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5311261
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D8UW47H17B
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198419-91-9
Created by
admin on Sat Dec 16 10:01:30 GMT 2023 , Edited by admin on Sat Dec 16 10:01:30 GMT 2023
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DTXSID2042563
Created by
admin on Sat Dec 16 10:01:30 GMT 2023 , Edited by admin on Sat Dec 16 10:01:30 GMT 2023
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ACTIVE MOIETY |
