MOZAFANCOGENE AUTOTEMCEL

U.S. Department of Health & Human Services Divider Arrow

National Institutes of Health Divider Arrow

NCATS

Approval Year

Substance Class	Structurally Diverse Created by `admin` on `Wed Apr 02 13:17:00 GMT 2025` Edited by `admin` on `Wed Apr 02 13:17:00 GMT 2025`
Source Materials Class	ORGANISM
Source Materials Type	AUTOLOGOUS HUMAN
Source Materials State	LIVE GENETICALLY MODIFIED
Source Materials Parent	`KG1PX42Z6Y` HOMO SAPEINS FETUS WHOLE
Part	blood
Fraction Material Type	cells
Fraction Name	hematopoietic cells
Record UNII	D82H29W72K
Record Status	`Validated (UNII)`
Record Version

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Name

Type

Language

RP-L102

Preferred Name

English

MOZAFANCOGENE AUTOTEMCEL

Official Name

English

MOZAFANCOGENE AUTOTEMCEL [USAN]

Common Name

English

mozafancogene autotemcel [INN]

Common Name

English

RP-L102 (A CELL THERAPY PRODUCT THAT CONSISTS OF AUTOLOGOUS GENETICALLY MODIFIED CD34+ HEMATOPOIETIC CELLS WITH A LENTIVIRAL VECTOR (LV) THAT ENCODES THE HUMAN FANCA GENE)

Common Name

English

Code System Code Type Description

FDA UNII

D82H29W72K

Created by admin on Wed Apr 02 13:17:00 GMT 2025 , Edited by admin on Wed Apr 02 13:17:00 GMT 2025

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SMS_ID

300000011640

Created by admin on Wed Apr 02 13:17:00 GMT 2025 , Edited by admin on Wed Apr 02 13:17:00 GMT 2025

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NCI_THESAURUS

C173602

Created by admin on Wed Apr 02 13:17:00 GMT 2025 , Edited by admin on Wed Apr 02 13:17:00 GMT 2025

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INN

11715

Created by admin on Wed Apr 02 13:17:00 GMT 2025 , Edited by admin on Wed Apr 02 13:17:00 GMT 2025

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USAN

HI-197

Created by admin on Wed Apr 02 13:17:00 GMT 2025 , Edited by admin on Wed Apr 02 13:17:00 GMT 2025

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Related Record Type Details


					D82H29W72K

MOZAFANCOGENE AUTOTEMCEL

ACTIVE MOIETY

Amount:

Agent Modifications

Modification Process	Modification Role	Modification Type	Amount	Fragment Name	Fragment ID
LENTIVIRAL TRANSFECTION				UNSPECIFIED SUBSTANCE	283d4948
CULTURE	CD34+ ENRICHMENT	BIOLOGICAL		UNSPECIFIED SUBSTANCE	9cd8c8f9

Structural Modifications

Modification Type	Location Site	Location Type	Residue Modified	Extent	Fragment Name	Fragment Approval
INSERTED GENE EXPRESSION VECTOR					UNSPECIFIED SUBSTANCE	b855b3ce (not in database)

Name	Property Type	Amount	Referenced Substance	Defining	Parameters	References
ANTIGEN EXPRESSED	BIOLOGICAL		`ZWL6BH0E0S` HEMATOPOIETIC PROGENITOR CELL ANTIGEN CD34