Details
| Stereochemistry | ACHIRAL |
| Molecular Formula | C10H14N2O |
| Molecular Weight | 178.231 |
| Optical Activity | NONE |
| Defined Stereocenters | 0 / 0 |
| E/Z Centers | 0 |
| Charge | 0 |
SHOW SMILES / InChI
SMILES
CC1=CC=CC(C)=C1NC(=O)CN
InChI
InChIKey=IXYVBZOSGGJWCW-UHFFFAOYSA-N
InChI=1S/C10H14N2O/c1-7-4-3-5-8(2)10(7)12-9(13)6-11/h3-5H,6,11H2,1-2H3,(H,12,13)
| Molecular Formula | C10H14N2O |
| Molecular Weight | 178.231 |
| Charge | 0 |
| Count |
|
| Stereochemistry | ACHIRAL |
| Additional Stereochemistry | No |
| Defined Stereocenters | 0 / 0 |
| E/Z Centers | 0 |
| Optical Activity | NONE |
Approval Year
PubMed
| Title | Date | PubMed |
|---|---|---|
| Chromatographic determination of free lidocaine and its active metabolites in plasma from patients under epidural anesthesia. | 2002 Nov |
|
| Effect of the CYP3A4 inhibitor erythromycin on the pharmacokinetics of lignocaine and its pharmacologically active metabolites in subjects with normal and impaired liver function. | 2003 Jan |
|
| Free lidocaine concentrations during continuous epidural anesthesia in geriatric patients. | 2003 May-Jun |
|
| Utility of nonaqueous capillary electrophoresis for the determination of lidocaine and its metabolites in human plasma: a comparison of ultraviolet and mass spectrometric detection. | 2004 |
|
| Cytochrome P450 1A2 is a major determinant of lidocaine metabolism in vivo: effects of liver function. | 2004 Jan |
|
| Effect of lidocaine on the minimum alveolar concentration of isoflurane in dogs. | 2004 Oct |
|
| Propofol does not inhibit lidocaine metabolism during epidural anesthesia. | 2004 Oct |
|
| Thrombosis as a conformational disease. | 2005 Feb |
|
| Differential effect of chronic renal failure on the pharmacokinetics of lidocaine in patients receiving and not receiving hemodialysis. | 2006 Dec |
|
| Determination of lidocaine and its two N-desethylated metabolites in dog and horse plasma by high-performance liquid chromatography combined with electrospray ionization tandem mass spectrometry. | 2007 Jun 1 |
|
| Serum concentrations of lidocaine and its metabolites after prolonged infusion in healthy horses. | 2008 Jun |
|
| Effect of erythromycin and rifampicin on monoethylglycinexylidide test. | 2008 Mar |
|
| [Determination of lidocaine and its metabolites in human plasma by liquid chromatography in combination with tandem mass spectrometry]. | 2010 Jul |
|
| Quantitative analysis of lignocaine and metabolites in equine urine and plasma by liquid chromatography-tandem mass spectrometry. | 2010 Jul 15 |
Patents
| Substance Class |
Chemical
Created
by
admin
on
Edited
Sat Dec 16 10:02:42 UTC 2023
by
admin
on
Sat Dec 16 10:02:42 UTC 2023
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| Record UNII |
D2D932W316
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| Record Status |
Validated (UNII)
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18865-38-8
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357241
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87833
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DTXSID40876064
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| Related Record | Type | Details | ||
|---|---|---|---|---|
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BINDER->LIGAND |
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| Related Record | Type | Details | ||
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PARENT -> METABOLITE LESS ACTIVE |
