GLYCINEXYLIDIDE

Details

Stereochemistry	ACHIRAL
Molecular Formula	C10H14N2O
Molecular Weight	178.231
Optical Activity	NONE
Defined Stereocenters	0 / 0
E/Z Centers	0
Charge	0

SHOW SMILES / InChI

Structure Search

SMILES

CC1=CC=CC(C)=C1NC(=O)CN

InChI

InChIKey=IXYVBZOSGGJWCW-UHFFFAOYSA-N

InChI=1S/C10H14N2O/c1-7-4-3-5-8(2)10(7)12-9(13)6-11/h3-5H,6,11H2,1-2H3,(H,12,13)

HIDE SMILES / InChI

Molecular Formula	C10H14N2O
Molecular Weight	178.231
Charge	0
Count

Stereochemistry	ACHIRAL
Additional Stereochemistry	No
Defined Stereocenters	0 / 0
E/Z Centers	0
Optical Activity	NONE

Approval Year

PubMed

Title	Date	PubMed
Involvement of liver carboxylesterases in the in vitro metabolism of lidocaine.	2002 Jun	12019189
Chromatographic determination of free lidocaine and its active metabolites in plasma from patients under epidural anesthesia.	2002 Nov	12698986
Effect of the CYP3A4 inhibitor erythromycin on the pharmacokinetics of lignocaine and its pharmacologically active metabolites in subjects with normal and impaired liver function.	2003 Jan	12534644
Free lidocaine concentrations during continuous epidural anesthesia in geriatric patients.	2003 May-Jun	12772139
Utility of nonaqueous capillary electrophoresis for the determination of lidocaine and its metabolites in human plasma: a comparison of ultraviolet and mass spectrometric detection.	2004	15481095
Cytochrome P450 1A2 is a major determinant of lidocaine metabolism in vivo: effects of liver function.	2004 Jan	14749694
Effect of lidocaine on the minimum alveolar concentration of isoflurane in dogs.	2004 Oct	15509291
Propofol does not inhibit lidocaine metabolism during epidural anesthesia.	2004 Oct	15385363
Thrombosis as a conformational disease.	2005 Feb	15710578
Differential effect of chronic renal failure on the pharmacokinetics of lidocaine in patients receiving and not receiving hemodialysis.	2006 Dec	17178261
Determination of lidocaine and its two N-desethylated metabolites in dog and horse plasma by high-performance liquid chromatography combined with electrospray ionization tandem mass spectrometry.	2007 Jun 1	17296334
Serum concentrations of lidocaine and its metabolites after prolonged infusion in healthy horses.	2008 Jun	18267881
Effect of erythromycin and rifampicin on monoethylglycinexylidide test.	2008 Mar	21279172
[Determination of lidocaine and its metabolites in human plasma by liquid chromatography in combination with tandem mass spectrometry].	2010 Jul	20848799
Quantitative analysis of lignocaine and metabolites in equine urine and plasma by liquid chromatography-tandem mass spectrometry.	2010 Jul 15	20566304

Patents

Substance Class	Chemical Created by `admin` on `Sat Dec 16 10:02:42 GMT 2023` Edited by `admin` on `Sat Dec 16 10:02:42 GMT 2023`
Record UNII	D2D932W316
Record Status	`Validated (UNII)`
Record Version

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Name

Type

Language

GLYCINEXYLIDIDE

Common Name

English

GLYCYLXYLIDIDE

Common Name

English

N-GLYCYL-2,6-XYLIDINE

Systematic Name

English

W-49167

Code

English

GX

Common Name

English

GLYCYL XYLIDIDE

Common Name

English

N-(2,6-DIMETHYLPHENYL)GLYCINAMIDE

Systematic Name

English

ASTRA-6204

Code

English

.OMEGA.-AMINO-2,6-DIMETHYLACETANILIDE

Systematic Name

English

N-(2,6-DIMETHYLPHENYL)-2-AMINOACETAMIDE

Systematic Name

English

2-AMINO-2',6'-DIMETHYLACETOANILIDE

Systematic Name

English

Code System Code Type Description

FDA UNII

D2D932W316