TRIPALMITIN

Details

Stereochemistry	ACHIRAL
Molecular Formula	C51H98O6
Molecular Weight	807.3202
Optical Activity	NONE
Defined Stereocenters	0 / 0
E/Z Centers	0
Charge	0

SHOW SMILES / InChI

Structure Search

SMILES

CCCCCCCCCCCCCCCC(=O)OCC(COC(=O)CCCCCCCCCCCCCCC)OC(=O)CCCCCCCCCCCCCCC

InChI

InChIKey=PVNIQBQSYATKKL-UHFFFAOYSA-N

InChI=1S/C51H98O6/c1-4-7-10-13-16-19-22-25-28-31-34-37-40-43-49(52)55-46-48(57-51(54)45-42-39-36-33-30-27-24-21-18-15-12-9-6-3)47-56-50(53)44-41-38-35-32-29-26-23-20-17-14-11-8-5-2/h48H,4-47H2,1-3H3

HIDE SMILES / InChI

Molecular Formula	C51H98O6
Molecular Weight	807.3202
Charge	0
Count

Stereochemistry	ACHIRAL
Additional Stereochemistry	No
Defined Stereocenters	0 / 0
E/Z Centers	0
Optical Activity	NONE

Description
Sources: https://www.ebi.ac.uk/chebi/searchId.do?chebiId=CHEBI:77393 | https://www.cir-safety.org/sites/default/files/trigly092017TAR.pdf

Tripalmitin is a triglyceride obtained by formal acylation of the three hydroxy groups of glycerol by palmitic (hexadecanoic) acid. It derives from a hexadecanoic acid. Tripalmitin is used as a skin conditioning agent.

Approval Year

PubMed

Title	Date	PubMed
Nondestructive rheological measurement of aqueous dispersions of solid lipid nanoparticles: effects of lipid types and concentrations on dispersion consistency.	2010-09	20184417
A rapid separation technique for overcoming suppression of triacylglycerols by phosphatidylcholine using MALDI-TOF MS.	2010-08	20447931
Optimisation of tripalmitin-rich fractionation from palm stearin by response surface methodology.	2010-07	20549806
Evolving neural network optimization of cholesteryl ester separation by reversed-phase HPLC.	2010-07	20490467
Regulation of hepatic gene expression by saturated fatty acids.	2010-03-16	20227267
Two-step solid lipid extrusion as a process to modify dissolution behavior.	2010-03	20309654
Investigating the relationship between drug distribution in solid lipid matrices and dissolution behaviour using Raman spectroscopy and mapping.	2010-03	19691104
Screening of food grade lipases to be used in esterification and interesterification reactions of industrial interest.	2010-02	19263247
Cellular stress responses: cell survival and cell death.	2010	20182529
Fatty acid selectivity of lipases during acidolysis reaction between oleic acid and monoacid triacylglycerols.	2009-11-11	19835376
Susceptibility of pancreatic beta cells to fatty acids is regulated by LXR/PPARalpha-dependent stearoyl-coenzyme A desaturase.	2009-09-29	19787047
Impact of surfactant properties on oxidative stability of beta-carotene encapsulated within solid lipid nanoparticles.	2009-09-09	19691283
Thermostable lipases from the extreme thermophilic anaerobic bacteria Thermoanaerobacter thermohydrosulfuricus SOL1 and Caldanaerobacter subterraneus subsp. tengcongensis.	2009-09	19579003
Lipase-catalyzed reactions at interfaces of two-phase systems and microemulsions.	2009-09	18795240
Tailor-made dissolution profiles by extruded matrices based on lipid polyethylene glycol mixtures.	2009-08-04	19358867
Proteins altered by elevated levels of palmitate or glucose implicated in impaired glucose-stimulated insulin secretion.	2009-07-16	19607692
Influence of structural variations on drug release from lipid/polyethylene glycol matrices.	2009-07-12	19406229
Solid lipid nanoparticles: a modern formulation approach in drug delivery system.	2009-07	20502539
Effect of surfactant surface coverage on formation of solid lipid nanoparticles (SLN).	2009-06-01	19380149
Effect of electromagnetic field and surface modification on the electrical behavior of novel solid lipid nanoparticles covered with l-arginine.	2009-06-01	19181492
Biochemical characterization of a putative wheat caffeic acid O-methyltransferase.	2009-04	19211254
Animal-derived surfactants for the treatment and prevention of neonatal respiratory distress syndrome: summary of clinical trials.	2009-02	19436610
Understanding the solid-state behaviour of triglyceride solid lipid extrudates and its influence on dissolution.	2009-01	18588976
Nanomedicine in pulmonary delivery.	2009	20054434
Biosynthesis of storage compounds by Rhodococcus jostii RHA1 and global identification of genes involved in their metabolism.	2008-12-12	19077282
Plant products for pharmacology: application of enzymes in their transformations.	2008-12	19330086
Polaron hopping in some biomolecular solids and their charge transfer complexes.	2008-12	19239130
Temperature scanning ultrasonic velocity study of complex thermal transformations in solid lipid nanoparticles.	2008-11-18	18925768
Modeling of the triglyceride-rich core in lipoprotein particles.	2008-11-06	18844397
Construction of a taste-blind medaka fish and quantitative assay of its preference-aversion behavior.	2008-11	18700838
Long-term exposure of mouse pancreatic islets to oleate or palmitate results in reduced glucose-induced somatostatin and oversecretion of glucagon.	2008-09	18622593
Composition of adipose tissue and marrow fat in humans by 1H NMR at 7 Tesla.	2008-09	18509197
Palmitate impairs and eicosapentaenoate restores insulin secretion through regulation of SREBP-1c in pancreatic islets.	2008-09	18458149
Lipid droplets: a classic organelle with new outfits.	2008-08	18546013
Structure-activity relationships of wheat flavone O-methyltransferase: a homodimer of convenience.	2008-05	18397325
Micro-scale flow cytometry-based and biochemical analysis of lipid signaling in primary B cell subpopulations.	2007-12-24	18385809
Ultrasonic scattering in chocolate and model systems containing sucrose, tripalmitin and olive oil.	2007-11	18051170
Slow recrystallization of tripalmitoylglycerol from MCT oil observed by 2H NMR.	2007-10-17	17880150
Mechanisms involved in the cytotoxic and cytoprotective actions of saturated versus monounsaturated long-chain fatty acids in pancreatic beta-cells.	2007-08	17641278
Effects of stereospecific positioning of fatty acids in triacylglycerol structures in native and randomized fats: a review of their nutritional implications.	2007-07-12	17625019
Production of solid lipid nanoparticle suspensions using supercritical fluid extraction of emulsions (SFEE) for pulmonary delivery using the AERx system.	2007-07-10	17582648
Enzymatic production of infant milk fat analogs containing palmitic acid: optimization of reactions by response surface methodology.	2007-05	17430912
Development and evaluation of nitrendipine loaded solid lipid nanoparticles: influence of wax and glyceride lipids on plasma pharmacokinetics.	2007-04-20	17161566
Enzymatic interesterification of tripalmitin with vegetable oil blends for formulation of caprine milk infant formula analogs.	2007-02	17235135
High-temperature micro liquid chromatography for lipid molecular species analysis with evaporative light scattering detection.	2007-01-26	17161844
Importance of solid lipid nanoparticles (SLN) in various administration routes and future perspectives.	2007	18019829
[Effect of crystallization temperature of palm oil on its crystallization. IV. The influence of tripalmitoylglycerol (PPP) on the crystallization of 1,3-dipalmitoyl-2-oleoyl-glycerol (POP) and 1,2-dioleoyl-3-palmitoyl-glycerol (POO)].	2007	17898485
Tripalmitin-based cationic lipospheres: preparation, characterization and in Lab-on-a-chip applications.	2006-11-28	17718971
Pharmacokinetics, tissue distribution and bioavailability of nitrendipine solid lipid nanoparticles after intravenous and intraduodenal administration.	2006-11	17090399
Human milk fat substitutes containing omega-3 fatty acids.	2006-05-17	19127750

Patents

Sample Use Guides

In Vivo Use Guide

Mice: tripalmitin (0--250 g fat/kg)

Route of Administration: Oral

Substance Class	Chemical Created by `admin` on `Mon Mar 31 17:56:51 GMT 2025` Edited by `admin` on `Mon Mar 31 17:56:51 GMT 2025`
Record UNII	D133ZRF50U
Record Status	`Validated (UNII)`
Record Version

Download

Name

Type

Language

TRIPALMITIN

Official Name

English

BAROLUB LCD

Preferred Name

English

tripalmitin [INN]

Common Name

English

1,2,3-PROPANETRIYL TRIHEXADECANOATE

Systematic Name

English

DYNASAN 116

Brand Name

English

TRIPALMITIN [MI]

Common Name

English

TRIPALMITOYLGLYCEROL

Systematic Name

English

SPEZIALFETT 116

Brand Name

English

GLYCEROL TRIPALMITATE

Systematic Name

English

GLYCERYL TRIHEXADECANOATE

Systematic Name

English

HEXADECANOIC ACID, 1,1',1''-(1,2,3-PROPANETRIYL) ESTER

Common Name

English

DYNOSAN 114

Brand Name

English

GLYCERYL TRIPALMITATE

Systematic Name

English

PALMITIC ACID TRIGLYCERIDE

Common Name

English

HEXADECANOIC ACID, 1,2,3-PROPANETRIYL ESTER

Common Name

English

Code System Code Type Description

WIKIPEDIA

TRIPALMITIN