EFLOXATE

U.S. Department of Health & Human Services Divider Arrow

National Institutes of Health Divider Arrow

NCATS

Details

Stereochemistry	ACHIRAL
Molecular Formula	C19H16O5
Molecular Weight	324.3273
Optical Activity	NONE
Defined Stereocenters	0 / 0
E/Z Centers	0
Charge	0

SHOW SMILES / InChI

Structure of EFLOXATE

Structure Search

SMILES

CCOC(=O)COC1=CC2=C(C=C1)C(=O)C=C(O2)C3=CC=CC=C3

InChI

InChIKey=ZVXBAHLOGZCFTP-UHFFFAOYSA-N

InChI=1S/C19H16O5/c1-2-22-19(21)12-23-14-8-9-15-16(20)11-17(24-18(15)10-14)13-6-4-3-5-7-13/h3-11H,2,12H2,1H3

HIDE SMILES / InChI

Molecular Formula	C19H16O5
Molecular Weight	324.3273
Charge	0
Count

Stereochemistry	ACHIRAL
Additional Stereochemistry	No
Defined Stereocenters	0 / 0
E/Z Centers	0
Optical Activity	NONE

Description
Sources: http://www.ncbi.nlm.nih.gov/pubmed/13816307
Curator's Comment: description was created based on several sources, including, http://www.recordati.com/en/about_us/history/

Efloxate is a coronary vasodilator developed in 1959 in Italy by Recordati and used for the treatment of angina pectoris. The drug is no longer marketed.

Originator

Approval Year

Conditions

Conditions

Condition	Modality	Targets	Highest Phase	Product
Angina pectoris 106 Sources: http://www.ncbi.nlm.nih.gov/pubmed/13816307	Primary		Approved 8429	RECORDIL Approved Use Unknown

PubMed

PubMed

Title	Date	PubMed

Sample Use Guides

In Vivo Use Guide

One 15 mg. tablet a day, gradually increased over 7 to 8 days to 3 or 4 tablets daily (45 to 60 mg.), and given over a period of at least three months.

Route of Administration: Oral

In Vitro Use Guide

Unknown

Substance Class	Chemical Created by `admin` on `Fri Dec 15 16:14:35 GMT 2023` Edited by `admin` on `Fri Dec 15 16:14:35 GMT 2023`
Record UNII	CZU6V3902K
Record Status	`Validated (UNII)`
Record Version

Download

Name

Type

Language

EFLOXATE

Official Name

English

EFLOXATE [JAN]

Common Name

English

ETHYL-((4-OXO-2-PHENYL-4H-1-BENZOPYRAN-7-YL)OXY) ACETATE

Systematic Name

English

Efloxate [WHO-DD]

Common Name

English

efloxate [INN]

Common Name

English

NSC-758891

Code

English

EFLOXATE [MI]

Common Name

English

EFLOXATE [MART.]

Common Name

English

Classification Tree Code System Code

NCI_THESAURUS

C29707

Created by admin on Fri Dec 15 16:14:35 GMT 2023 , Edited by admin on Fri Dec 15 16:14:35 GMT 2023

WHO-VATC

QC01DX13

Created by admin on Fri Dec 15 16:14:35 GMT 2023 , Edited by admin on Fri Dec 15 16:14:35 GMT 2023

WHO-ATC

C01DX13

Created by admin on Fri Dec 15 16:14:35 GMT 2023 , Edited by admin on Fri Dec 15 16:14:35 GMT 2023

Code System Code Type Description

NCI_THESAURUS

C74416

Created by admin on Fri Dec 15 16:14:35 GMT 2023 , Edited by admin on Fri Dec 15 16:14:35 GMT 2023

PRIMARY

MESH

C005472

Created by admin on Fri Dec 15 16:14:35 GMT 2023 , Edited by admin on Fri Dec 15 16:14:35 GMT 2023

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ChEMBL

CHEMBL1349073

Created by admin on Fri Dec 15 16:14:35 GMT 2023 , Edited by admin on Fri Dec 15 16:14:35 GMT 2023

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DRUG CENTRAL

991

Created by admin on Fri Dec 15 16:14:35 GMT 2023 , Edited by admin on Fri Dec 15 16:14:35 GMT 2023

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EVMPD

SUB06469MIG

Created by admin on Fri Dec 15 16:14:35 GMT 2023 , Edited by admin on Fri Dec 15 16:14:35 GMT 2023

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WIKIPEDIA

EFLOXATE

Created by admin on Fri Dec 15 16:14:35 GMT 2023 , Edited by admin on Fri Dec 15 16:14:35 GMT 2023

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FDA UNII

CZU6V3902K

Created by admin on Fri Dec 15 16:14:35 GMT 2023 , Edited by admin on Fri Dec 15 16:14:35 GMT 2023

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RXCUI

23852

Created by admin on Fri Dec 15 16:14:35 GMT 2023 , Edited by admin on Fri Dec 15 16:14:35 GMT 2023

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RxNorm

EPA CompTox

DTXSID3048736

Created by admin on Fri Dec 15 16:14:35 GMT 2023 , Edited by admin on Fri Dec 15 16:14:35 GMT 2023

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CAS

119-41-5

Created by admin on Fri Dec 15 16:14:35 GMT 2023 , Edited by admin on Fri Dec 15 16:14:35 GMT 2023

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MERCK INDEX

m1129

Created by admin on Fri Dec 15 16:14:35 GMT 2023 , Edited by admin on Fri Dec 15 16:14:35 GMT 2023

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Merck Index

INN

1452

Created by admin on Fri Dec 15 16:14:35 GMT 2023 , Edited by admin on Fri Dec 15 16:14:35 GMT 2023

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ECHA (EC/EINECS)

204-321-9

Created by admin on Fri Dec 15 16:14:35 GMT 2023 , Edited by admin on Fri Dec 15 16:14:35 GMT 2023

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PUBCHEM

8395

Created by admin on Fri Dec 15 16:14:35 GMT 2023 , Edited by admin on Fri Dec 15 16:14:35 GMT 2023

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DRUG BANK

DB13333

Created by admin on Fri Dec 15 16:14:35 GMT 2023 , Edited by admin on Fri Dec 15 16:14:35 GMT 2023

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NSC

758891

Created by admin on Fri Dec 15 16:14:35 GMT 2023 , Edited by admin on Fri Dec 15 16:14:35 GMT 2023

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SMS_ID

100000080516

Created by admin on Fri Dec 15 16:14:35 GMT 2023 , Edited by admin on Fri Dec 15 16:14:35 GMT 2023

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Related Record Type Details


					CZU6V3902K

EFLOXATE

ACTIVE MOIETY