TETULOMAB TETRAXETAN LU-177

Investigational

Approval Year

Substance Class	Protein
Protein Type	MONOCLONAL ANTIBODY
Protein Sub Type	IGG1
Sequence Origin	MOUSE
Sequence Type	COMPLETE
Record UNII	CPW7BR9UY7
Record Status	`Validated (UNII)`
Record Version

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Name

Type

Language

TETULOMAB TETRAXETAN LU-177

Common Name

English

(SUP 177)LU-TETULOMAB

Preferred Name

English

ANTI-CD37 ANTIBODY TETULOMAB TETRAXETAN LU-177

Common Name

English

177LU-TETULOMAB

Common Name

English

177LU-TETRAXETAN-TETULOMAB

Common Name

English

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Classification Tree

Code System

Code

Designated

FDA ORPHAN DRUG

433014

Positive

EU-Orphan Drug

EU/03/14/1271

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Code System

Code

Type

Description

DRUG BANK

DB12227

PRIMARY

FDA UNII

CPW7BR9UY7

PRIMARY

NCI_THESAURUS

C105403

PRIMARY

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Related Record

Type

Details


					VTD13G7FDK

LEUKOCYTE ANTIGEN CD37

TARGET -> INHIBITOR

Amount:

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Related Record

Type

Details


					CPW7BR9UY7

TETULOMAB TETRAXETAN LU-177

ACTIVE MOIETY

Amount:

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Structural Modifications

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Modification Type	Location Site	Location Type	Residue Modified	Extent	Fragment Name	Fragment Approval
AMINO_ACID_SUBSTITUTION		RESIDUE_SPECIFIC	K	Amount: MOLE RATION [5 to 6] (limits)	LYSINE .EPISILON.CARBAMOTHIOBENZYL-2-TETRAXAN	6QU69VIG75
MOIETY		RESIDUE_SPECIFIC	Lysine	Amount: MOLE RATIO [5 to 6] (limits)	LUTETIUM LU-177 CATION	7BMT0JDQ3M

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Name	Property Type	Amount	Referenced Substance	Defining	Parameters	References
Molecular Formula	CHEMICAL	ESTIMATED
MOL_WEIGHT:NUMBER AVERAGE(MASS SPECTROMETRY)	CHEMICAL	NUMBER AVERAGE 151731 Da (average)

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