Crebankitug

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National Institutes of Health Divider Arrow

NCATS

Approval Year

Substance Class	Protein Created by `admin` on `Tue Apr 01 21:57:13 GMT 2025` Edited by `admin` on `Tue Apr 01 21:57:13 GMT 2025`
Protein Type	MONOCLONAL ANTIBODY
Protein Sub Type	IGG1\|LAMDA
Sequence Origin	HUMAN
Sequence Type	COMPLETE
Record UNII	CP5EMC5O5G
Record Status	`Validated (UNII)`
Record Version

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Name

Type

Language

Crebankitug

Official Name

English

H-gamma1 heavy chain Homo sapiens (1-447) [VH (Homo sapiens IGHV3-43D*03 (87.8%) -(IGHD) -IGHJ4*01 (100%), CDR-IMGT [8.8.10] (26-33.51-58.97-106)) (1-117) -Homo sapiens IGHG1*03v (100%), G1m3>G1m17, nG1m1 CH1 K120, CH3 E12, M14 (CH1 R120>K (214) (118-215

Preferred Name

English

Immunoglobulin G1, anti-(human/Macaca fascicularis interleukin-7 receptor subunit ?) (human monoclonal ZB-168 ?1-chain), disulfide with human monoclonal ZB-168 ?-chain, dimer

Common Name

English

immunoglobulin G1-lambda2, anti-[Homo sapiens IL7R (interleukin 7 receptor, IL7RA, CD127)], Homo sapiens monoclonal antibody

Common Name

English

crebankitug [INN]

Common Name

English

Code System Code Type Description

INN

13072

Created by admin on Tue Apr 01 21:57:13 GMT 2025 , Edited by admin on Tue Apr 01 21:57:13 GMT 2025

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CAS

2893793-17-2

Created by admin on Tue Apr 01 21:57:13 GMT 2025 , Edited by admin on Tue Apr 01 21:57:13 GMT 2025

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SMS_ID

300000054793

Created by admin on Tue Apr 01 21:57:13 GMT 2025 , Edited by admin on Tue Apr 01 21:57:13 GMT 2025

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FDA UNII

CP5EMC5O5G

Created by admin on Tue Apr 01 21:57:13 GMT 2025 , Edited by admin on Tue Apr 01 21:57:13 GMT 2025

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NCI_THESAURUS

C206896

Created by admin on Tue Apr 01 21:57:13 GMT 2025 , Edited by admin on Tue Apr 01 21:57:13 GMT 2025

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From	To
1_22	1_96
1_144	1_200
1_220	3_215
1_226	2_226
1_229	2_229
1_261	1_321
1_367	1_425
2_22	2_96
2_144	2_200
2_220	4_215
2_261	2_321
2_367	2_425
3_22	3_91
3_138	3_197
4_22	4_91
4_138	4_197

Glycosylation Type

MAMMALIAN

Glycosylation Link Type	Site
N	1_297
N	2_297

Related Record Type Details


					9J9913QZ47

INTERLEUKIN-7 RECEPTOR SUBUNIT ALPHA

TARGET -> INHIBITOR

Amount:

Related Record Type Details


					CP5EMC5O5G

ACTIVE MOIETY

Amount:

Structural Modifications

Modification Type	Location Site	Location Type	Residue Modified	Extent	Fragment Name	Fragment Approval
AMINO ACID REMOVAL	[1_447] [2_447]	C-TERMINUS			LYSINE	K3Z4F929H6

Name	Property Type	Amount	Referenced Substance	Defining	Parameters	References
MOL_WEIGHT:NUMBER(CALCULATED)	CHEMICAL
Molecular Formula	CHEMICAL