U.S. Department of Health & Human Services Divider Arrow National Institutes of Health Divider Arrow NCATS

Approval Year

Substance Class Structurally Diverse
Created
by admin
on Sat Dec 16 19:49:17 UTC 2023
Edited
by admin
on Sat Dec 16 19:49:17 UTC 2023
Source Materials Class ORGANISM
Source Materials Type ALLOGENIC HUMAN
Source Materials State ALLOGENIC
Source Materials Parent
Part BLOOD CELL
Fraction Material Type CELL
Fraction Name T-cells
Record UNII
CH357NR3E3
Record Status Validated (UNII)
Record Version
  • Download
Name Type Language
Posoleucel
INN  
Official Name English
posoleucel [INN]
Common Name English
Viralym-M
Common Name English
ALVR-105
Common Name English
ALVR105
Common Name English
Code System Code Type Description
FDA UNII
CH357NR3E3
Created by admin on Sat Dec 16 19:49:18 UTC 2023 , Edited by admin on Sat Dec 16 19:49:18 UTC 2023
PRIMARY
INN
11363
Created by admin on Sat Dec 16 19:49:18 UTC 2023 , Edited by admin on Sat Dec 16 19:49:18 UTC 2023
PRIMARY
Related Record Type Details
TARGET ORGANISM->INHIBITOR
T-cells to eliminate actively expressing cells and provide T-cell help for antibody production
TARGET ORGANISM->INHIBITOR
T-cells to eliminate actively expressing cells and provide T-cell help for antibody production
TARGET ORGANISM->INHIBITOR
T-cells to eliminate actively expressing cells and provide T-cell help for antibody production
TARGET ORGANISM->INHIBITOR
T-cells to eliminate actively expressing cells and provide T-cell help for antibody production
TARGET ORGANISM->INHIBITOR
T-cells to eliminate actively expressing cells and provide T-cell help for antibody production
Related Record Type Details
ACTIVE MOIETY

Agent Modifications

Modification Process Modification Role Modification Type Amount Fragment Name Fragment ID
IMMUNOSELECTION IMMUNIZATION IMMUNOLOGICAL EBNA1 Pool of 158 peptides derived from a peptide scan (15mers with 11 aa overlap) through Epstein-Barr nuclear antigen Q9E9PR7B6Q
IMMUNOSELECTION IMMUNIZATION IMMUNOLOGICAL BKV (capsid protein VP1) Pool of 88 peptides derived from a peptide scan (15mers with 11 aa overlap) through Major capsid protein VP1 of BK Polyomavirus (BKV). 4CH7FZ6E46
IMMUNOSELECTION IMMUNIZATION IMMUNOLOGICAL PM-HAdV3 (Pool of 234 peptides derived from a peptide scan (15mers with 11 aa overlap) through Hexon protein of Human Adenovirus (HAdV) - type B serotype 3) J4MA6E23JR
CULTURE EXPANSION BIOLOGICAL FETAL SERUM, BOVINE K5DD3J879P
IMMUNOSELECTION IMMUNIZATION IMMUNOLOGICAL HCMVA (pp65) Pool of 138 peptides derived from a peptide scan (15mers with 11 aa overlap) through 65 kDa phosphoprotein (pp65) of Human Cytomegalovirus (HCMV) J5DSL6YTT4
IMMUNOSELECTION IMMUNIZATION IMMUNOLOGICAL UNSPECIFIED SUBSTANCE 6c57757b
IMMUNOSELECTION IMMUNIZATION IMMUNOLOGICAL HAdV-5 (penton protein) Pool of 140 peptides derived from a peptide scan (15mers with 11 aa overlap) through Penton protein of Human Adenovirus (HAdV) - type B serotype 5. MH8T3997YU
IMMUNOSELECTION IMMUNIZATION IMMUNOLOGICAL PM-EBV-LMP2 (Pool of 122 peptides derived from a peptide scan (15mers with 11 aa overlap) through Latent membrane protein 2) HBS7T95QAY
IMMUNOSELECTION IMMUNIZATION IMMUNOLOGICAL UNSPECIFIED SUBSTANCE 80422dd1
IMMUNOSELECTION IMMUNIZATION IMMUNOLOGICAL Pool of 267 peptides derived from a peptide scan (15mers with 11 aa overlap) through Protein U90 of Human Herpesvirus 6 (HHV6) Z6DY4N885S
IMMUNOSELECTION IMMUNIZATION IMMUNOLOGICAL BK Virus large T antigen pool of 170 peptides derived from a peptide scan (15mers with 11 aa overlap) through Large T antigen of BK Polyomavirus (BKV) TL8W7SNX67
IMMUNOSELECTION IMMUNIZATION IMMUNOLOGICAL UNSPECIFIED SUBSTANCE 33602785
CULTURE EXPANSION CELL ACTIVATION INTERLEUKIN-7 HUMAN RECOMBINANT 418XB47Y71
IMMUNOSELECTION IMMUNIZATION IMMUNOLOGICAL EBV-BZLF1 Pool of 59 peptides derived from a peptide scan (15mers with 11 aa overlap) through BZLF1 Trans-activator protein of Epstein-Barr Virus UM8KG98JRF
CULTURE EXPANSION CELL ACTIVATION Recombinant Human IL-4 non-glycosylated, N-terminal Methionine V73MKE6TE2
Name Property Type Amount Referenced Substance Defining Parameters References
HLA MATCH BIOLOGICAL