Approval Year
| Substance Class |
Protein
Created
by
admin
on
Edited
Sat Dec 16 19:55:24 GMT 2023
by
admin
on
Sat Dec 16 19:55:24 GMT 2023
|
| Protein Type | ENZYME |
| Protein Sub Type | METHYLTRANSFERASE |
| Sequence Origin | HUMAN |
| Sequence Type | COMPLETE |
| Record UNII |
CAU4JAJ646
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| Record Status |
Validated (UNII)
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| Record Version |
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-
Download
| Name | Type | Language | ||
|---|---|---|---|---|
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Common Name | English | ||
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Common Name | English |
| Code System | Code | Type | Description | ||
|---|---|---|---|---|---|
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P50135
Created by
admin on Sat Dec 16 19:55:25 GMT 2023 , Edited by admin on Sat Dec 16 19:55:25 GMT 2023
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PRIMARY | |||
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CAU4JAJ646
Created by
admin on Sat Dec 16 19:55:25 GMT 2023 , Edited by admin on Sat Dec 16 19:55:25 GMT 2023
|
PRIMARY |
| Related Record | Type | Details | ||
|---|---|---|---|---|
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SUBSTRATE -> METABOLIC ENZYME |
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INHIBITOR->OFF-TARGET |
HNMT inhibitors may increase histamine levels in peripheral tissues and exacerbate histamine-related diseases, such as allergic rhinitis, urticaria, and peptic ulcer disease. However, the effect of HNMT inhibitors on brain function is not yet fully understood. Some studies suggest that an increase in brain histamine levels by novel HNMT inhibitors could contribute to the improvement of brain disorders.
IC50
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NON-INHIBITOR->OFF TARGET |
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INHIBITOR->OFF-TARGET |
IC50
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| Name | Property Type | Amount | Referenced Substance | Defining | Parameters | References |
|---|---|---|---|---|---|---|
| MOL_WEIGHT:NUMBER(CALCULATED) | CHEMICAL |
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| Molecular Formula | CHEMICAL |
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