Details
| Stereochemistry | ACHIRAL |
| Molecular Formula | C20H18O4 |
| Molecular Weight | 322.3545 |
| Optical Activity | NONE |
| Defined Stereocenters | 0 / 0 |
| E/Z Centers | 0 |
| Charge | 0 |
SHOW SMILES / InChI
SMILES
CC1(C)OC2=C(C=CC(O)=C2C=C1)C3=CC4=CC=C(O)C=C4OC3
InChI
InChIKey=NGGYSPUAKQMTNP-UHFFFAOYSA-N
InChI=1S/C20H18O4/c1-20(2)8-7-16-17(22)6-5-15(19(16)24-20)13-9-12-3-4-14(21)10-18(12)23-11-13/h3-10,21-22H,11H2,1-2H3
| Molecular Formula | C20H18O4 |
| Molecular Weight | 322.3545 |
| Charge | 0 |
| Count |
|
| Stereochemistry | ACHIRAL |
| Additional Stereochemistry | No |
| Defined Stereocenters | 0 / 0 |
| E/Z Centers | 0 |
| Optical Activity | NONE |
Approval Year
| Substance Class |
Chemical
Created
by
admin
on
Edited
Mon Mar 31 21:15:37 GMT 2025
by
admin
on
Mon Mar 31 21:15:37 GMT 2025
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| Record UNII |
C6Y321Q75O
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| Record Status |
Validated (UNII)
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| Record Version |
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Common Name | English | ||
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Preferred Name | English |
| Code System | Code | Type | Description | ||
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480774
Created by
admin on Mon Mar 31 21:15:37 GMT 2025 , Edited by admin on Mon Mar 31 21:15:37 GMT 2025
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60008-03-9
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admin on Mon Mar 31 21:15:37 GMT 2025 , Edited by admin on Mon Mar 31 21:15:37 GMT 2025
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C6Y321Q75O
Created by
admin on Mon Mar 31 21:15:37 GMT 2025 , Edited by admin on Mon Mar 31 21:15:37 GMT 2025
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Glabrene
Created by
admin on Mon Mar 31 21:15:37 GMT 2025 , Edited by admin on Mon Mar 31 21:15:37 GMT 2025
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DTXSID90208715
Created by
admin on Mon Mar 31 21:15:37 GMT 2025 , Edited by admin on Mon Mar 31 21:15:37 GMT 2025
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PRIMARY |
| Related Record | Type | Details | ||
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PARENT -> CONSTITUENT ALWAYS PRESENT | |||
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PARENT -> CONSTITUENT ALWAYS PRESENT |
Minimum Inhibitory Concentration (MIC) for Staphylococcus aureus (ATCC 13709) = 25 mcg ml and Mycobacterium smegmatis (ATCC 6371) = 25 mcg ml.
Extracts of G. glabra var. typica (Spanish licorice)-but not var. grandulifera (Russian licorice) were repeatedly active in the screen.
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PARENT -> CONSTITUENT ALWAYS PRESENT |
GLABRENE showed antibacterial activity against MSSAs (strains FDA 209P and Smith) and MRSAs(strains K3 and ST 28) (MICs 1.56?25 ug/ml). This compound exhibited antimicrobial activity against Micrococcus luteus ATCC 9341 and Bacillus subtilis PCI 219 (MICs 3.13?25 ug/ml) but not against Klebsiella pneumoniae PCI 602 and Pseudomonas aeruginosa IFO 3445.
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