IFINATAMAB DERUXTECAN

U.S. Department of Health & Human Services Divider Arrow

National Institutes of Health Divider Arrow

NCATS

Approval Year

Substance Class	Protein Created by `admin` on `Wed Apr 02 05:11:11 GMT 2025` Edited by `admin` on `Wed Apr 02 05:11:11 GMT 2025`
Protein Type	MONOCLONAL ANTIBODY CONJUGATE
Protein Sub Type	IGG1
Sequence Origin	HUMANIZED MOUSE
Sequence Type	COMPLETE
Record UNII	C6I0GC0GX5
Record Status	`Validated (UNII)`
Record Version

Download

Name

Type

Language

DS-7300A

Preferred Name

English

IFINATAMAB DERUXTECAN

Official Name

English

ifinatamab deruxtecan [INN]

Common Name

English

Ifinatamab deruxtecan [WHO-DD]

Common Name

English

IMMUNOGLOBULIN G1, ANTI-(HUMAN B7 HOMOLOG 3 PROTEIN) (HUMAN-MUS MUSCULUS MONOCLONAL MABX-9001A .GAMMA.1-CHAIN), DISULFIDE WITH HUMAN-MUS MUSCULUS MONOCLONAL MABX-9001A .KAPPA.-CHAIN, DIMER, THIOETHER WITH N-(6-(3-MERCAPTO-2,5-DIOXO-1-PYRROLIDINYL)-1-OXOH

Common Name

English

DS7300A

Code

English

MABX-9001A CYSTEINYL-DERUXTECAN

Common Name

English

IFINATAMAB DERUXTECAN [USAN]

Common Name

English

Classification Tree Code System Code

FDA ORPHAN DRUG

935123

Created by admin on Wed Apr 02 05:11:11 GMT 2025 , Edited by admin on Wed Apr 02 05:11:11 GMT 2025

Code System Code Type Description

CAS

2484870-92-8

Created by admin on Wed Apr 02 05:11:11 GMT 2025 , Edited by admin on Wed Apr 02 05:11:11 GMT 2025

PRIMARY

INN

11954

Created by admin on Wed Apr 02 05:11:11 GMT 2025 , Edited by admin on Wed Apr 02 05:11:11 GMT 2025

PRIMARY

FDA UNII

C6I0GC0GX5

Created by admin on Wed Apr 02 05:11:11 GMT 2025 , Edited by admin on Wed Apr 02 05:11:11 GMT 2025

PRIMARY

NCI_THESAURUS

C171577

Created by admin on Wed Apr 02 05:11:11 GMT 2025 , Edited by admin on Wed Apr 02 05:11:11 GMT 2025

PRIMARY

SMS_ID

300000040972

Created by admin on Wed Apr 02 05:11:11 GMT 2025 , Edited by admin on Wed Apr 02 05:11:11 GMT 2025

PRIMARY

USAN

NO-11

Created by admin on Wed Apr 02 05:11:11 GMT 2025 , Edited by admin on Wed Apr 02 05:11:11 GMT 2025

PRIMARY

Glycosylation Type

MAMMALIAN

Glycosylation Link Type	Site
N	1_302
N	2_302

Related Record Type Details


					961Y201EWR

TARGET->CONJUGATED TOXIN

Amount:


					4K42H9EDW7

PARENT -> CONJUGATE

Amount:

Related Record Type Details


					OQM5SD32BQ

N-[(1S,9S)-9-Ethyl-5-fluoro-2,3,9,10,13,15-hexahydro-9-hydroxy-4-methyl-10,13-dioxo-1H,12H-benzo[de]pyrano[3?,4?:6,7]indolizino[1,2-b]quinolin-1-yl]-2-hydroxyacetamide

PARENT -> METABOLITE ACTIVE

Amount:

Related Record Type Details


					C6I0GC0GX5

IFINATAMAB DERUXTECAN

ACTIVE MOIETY

Amount:

Structural Modifications

Modification Type	Location Site	Location Type	Residue Modified	Extent	Fragment Name	Fragment Approval
AMINO_ACID_SUBSTITUTION		RESIDUE_SPECIFIC		Amount:	CYSTEINYL DERUXTECAN	I1NS1DHT5R

Name	Property Type	Amount	Referenced Substance	Defining	Parameters	References
Molecular Formula	CHEMICAL
MOL_WEIGHT:NUMBER(CALCULATED)	CHEMICAL