Details
Stereochemistry | ABSOLUTE |
Molecular Formula | 2C21H37FN2O3S.C4H4O4 |
Molecular Weight | 949.259 |
Optical Activity | UNSPECIFIED |
Defined Stereocenters | 2 / 2 |
E/Z Centers | 1 |
Charge | 0 |
SHOW SMILES / InChI
SMILES
OC(=O)\C=C\C(O)=O.CCN(CCCCCC(C)(C)F)CCC[C@H](O)C1=CC=C(NS(C)(=O)=O)C=C1.CCN(CCCCCC(C)(C)F)CCC[C@H](O)C2=CC=C(NS(C)(=O)=O)C=C2
InChI
InChIKey=ODFOUAATRQAOLG-MMSVOLSESA-N
InChI=1S/2C21H37FN2O3S.C4H4O4/c2*1-5-24(16-8-6-7-15-21(2,3)22)17-9-10-20(25)18-11-13-19(14-12-18)23-28(4,26)27;5-3(6)1-2-4(7)8/h2*11-14,20,23,25H,5-10,15-17H2,1-4H3;1-2H,(H,5,6)(H,7,8)/b;;2-1+/t2*20-;/m00./s1
Molecular Formula | C21H37FN2O3S |
Molecular Weight | 416.593 |
Charge | 0 |
Count |
|
Stereochemistry | ABSOLUTE |
Additional Stereochemistry | No |
Defined Stereocenters | 1 / 1 |
E/Z Centers | 0 |
Optical Activity | UNSPECIFIED |
Molecular Formula | C4H4O4 |
Molecular Weight | 116.0722 |
Charge | 0 |
Count |
|
Stereochemistry | ACHIRAL |
Additional Stereochemistry | No |
Defined Stereocenters | 0 / 0 |
E/Z Centers | 1 |
Optical Activity | NONE |
Trecetilide is a class III antiarrhythmic agent developed for the treatment of atrial flutter and fibrillation. Trecetilide probably has effects on the cardiac myocyte membrane that are similar to ibutilide. It is being developed for both oral and intravenous administration. Unlike ibutilide, trecetilide has good oral bioavailability. Trecetilide has a good metabolic stability. As with ibutilide, its mechanism of class III action may involve both rectifier K+ current blockade and other mechanisms of prolonging repolarization.
Approval Year
Substance Class |
Chemical
Created
by
admin
on
Edited
Fri Dec 15 16:06:44 GMT 2023
by
admin
on
Fri Dec 15 16:06:44 GMT 2023
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Record UNII |
C4D4FJ1455
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Record Status |
Validated (UNII)
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Record Version |
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-
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Common Name | English |
Classification Tree | Code System | Code | ||
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NCI_THESAURUS |
C47793
Created by
admin on Fri Dec 15 16:06:44 GMT 2023 , Edited by admin on Fri Dec 15 16:06:44 GMT 2023
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Code System | Code | Type | Description | ||
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C117132
Created by
admin on Fri Dec 15 16:06:44 GMT 2023 , Edited by admin on Fri Dec 15 16:06:44 GMT 2023
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PRIMARY | |||
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C81428
Created by
admin on Fri Dec 15 16:06:44 GMT 2023 , Edited by admin on Fri Dec 15 16:06:44 GMT 2023
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PRIMARY | |||
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6441132
Created by
admin on Fri Dec 15 16:06:44 GMT 2023 , Edited by admin on Fri Dec 15 16:06:44 GMT 2023
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PRIMARY | |||
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191349-60-7
Created by
admin on Fri Dec 15 16:06:44 GMT 2023 , Edited by admin on Fri Dec 15 16:06:44 GMT 2023
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PRIMARY | |||
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CHEMBL269446
Created by
admin on Fri Dec 15 16:06:44 GMT 2023 , Edited by admin on Fri Dec 15 16:06:44 GMT 2023
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PRIMARY | |||
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JJ-68
Created by
admin on Fri Dec 15 16:06:44 GMT 2023 , Edited by admin on Fri Dec 15 16:06:44 GMT 2023
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PRIMARY | |||
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C4D4FJ1455
Created by
admin on Fri Dec 15 16:06:44 GMT 2023 , Edited by admin on Fri Dec 15 16:06:44 GMT 2023
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PRIMARY |
Related Record | Type | Details | ||
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PARENT -> SALT/SOLVATE | |||
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PARENT -> SALT/SOLVATE |
Related Record | Type | Details | ||
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ACTIVE MOIETY |