ISOBUTANE

Possibly Marketed Outside US

Details

Stereochemistry	ACHIRAL
Molecular Formula	C4H10
Molecular Weight	58.1222
Optical Activity	NONE
Defined Stereocenters	0 / 0
E/Z Centers	0
Charge	0

SHOW SMILES / InChI

Structure Search

SMILES

CC(C)C

InChI

InChIKey=NNPPMTNAJDCUHE-UHFFFAOYSA-N

InChI=1S/C4H10/c1-4(2)3/h4H,1-3H3

HIDE SMILES / InChI

Molecular Formula	C4H10
Molecular Weight	58.1222
Charge	0
Count

Stereochemistry	ACHIRAL
Additional Stereochemistry	No
Defined Stereocenters	0 / 0
E/Z Centers	0
Optical Activity	NONE

Description
Sources: https://www.ncbi.nlm.nih.gov/pubmed/20055182

Isobutane was used as a propellant for aerosol cans and foam products. It was studied as a potential substitute candidate for screen non-chlorofluorocarbon (CFC) metered dose inhaler (MDI) propellant.

Approval Year

PubMed

Title	Date	PubMed
Comparative efficiencies of isopropyl and tert-butyl alcohols for extracting zeins from maize endosperm.	2002-07-03	12083896
Synthesis of novel quaternary amino acids using molybdenum-catalyzed asymmetric allylic alkylation.	2002-06-26	12071719
Antifungal agents. 10. New derivatives of 1-[(aryl)[4-aryl-1H-pyrrol-3-yl]methyl]-1H-imidazole, synthesis, anti-candida activity, and quantitative structure-analysis relationship studies.	2002-06-20	12061875
Conversion of tricoordinate to hexacoordinate phosphorus. Formation of a phosphorane-phosphatrane system.	2002-06-19	12059227
Unique dual fluorescence of sterically congested hexaalkyl benzenehexacarboxylates: mechanism and application to viscosity probing.	2002-06-19	12059217
Synthesis and characterization of an air-stable gallium hydride, [t-Bu(H)Ga(mu-NEt(2))](2), and related chloride derivatives.	2002-06-03	12033900
Design and development of highly effective Lewis acid catalysts for enantioselective Diels-Alder reactions.	2002-05-29	12022822
Regarding the stability of d(0) monocyclopentadienyl zirconium acetamidinate complexes bearing alkyl substituents with beta-hydrogens.	2002-05-29	12022813
Simultaneous determination of preservatives in beverages, vinegar, aqueous sauces, and quasi-drug drinks by stir-bar sorptive extraction (SBSE) and thermal desorption GC-MS.	2002-05	12012172
In vivo protective effect of protocatechuic acid on tert-butyl hydroperoxide-induced rat hepatotoxicity.	2002-05	11955669
Synthesis and biological properties of amino acid amide ligand-based pyridinioalkanoyl thioesters as anti-HIV agents.	2002-05	11886789
Coupling of isoprenoid triflates with organoboron nucleophiles: synthesis and biological evaluation of geranylgeranyl diphosphate analogues.	2002-05	11886785
Tertiary pentyl groups enhance salen titanium catalyst for highly enantioselective trimethylsilylcyanation of aldehydes.	2002-04-19	11950323
Conformational studies by dynamic NMR. 88.(1) stereomutation processes in the diastereoisomers of a representative amino alcohol and related amide precursors.	2002-04-19	11950313
Endo-oxacyclizations of polyepoxides: biomimetic synthesis of fused polycyclic ethers.	2002-04-19	11950296
Regioselective metabolism of taxoids by human CYP3A4 and 2C8: structure-activity relationship.	2002-04	11901098
Transformation of mutagenic aromatic amines into non-mutagenic species by alkyl substituents. Part II: alkylation far away from the amino function.	2002-03-25	11909752
Nickel complexes of bidentate [S2] and [SN] borato ligands.	2002-03-25	11896705
Formation of a 1-bicyclo[1.1.1]pentyl anion and an experimental determination of the acidity and C-H bond dissociation energy of 3-tert-butylbicyclo[1.1.1]pentane.	2002-03-20	11890831
Tunneling and sterically induced ring puckering in a substituted [8]annulene anion radical.	2002-03-20	11890821
Quantitative determination of n-propane, iso-butane, and n-butane by headspace GC-MS in intoxications by inhalation of lighter fluid.	2002-03-14	11890178
Behavior and characteristics of amine derivatives obtained with o-phthaldialdehyde/3-mercaptopropionic acid and with o-phthaldialdehyde/N-acetyl-L-cysteine reagents.	2002-03-08	11999740
Natural deuterium distribution in branched-chain medium-length fatty acids is nonstatistical: a site-specific study by quantitative 2H NMR spectroscopy of the fatty acids of capsaicinoids.	2002-03-01	11921400
Antioxidant properties of silybin glycosides.	2002-03	11933137
Antifungal amides from Piper arboreum and Piper tuberculatum.	2002-03	11853747
Palladium(0)-catalyzed enantioselective O,S-rearrangement of racemic O-allylic thiocarbamates: a new entry to enantioenriched allylic sulfur compounds.	2002-02-22	11846656
X-ray structures of the first platinum complexes with Z configuration iminoether ligands: trans-dichlorobis(1-imino-1-methoxy-2,2'-dimethylpropane)platinum(II) and trans-tetrachlorobis(1-imino-1-methoxy-2,2'-dimethylpropane)platinum(IV).	2002-02-11	11825073
Quantitative structure-activity studies of insect growth regulators: XIX. Effects of substituents on the aromatic moiety of dibenzoylhydrazines on larvicidal activity against the beet armyworm Spodoptera exigua.	2002-02	11852637
Sensitive markers used to identify compounds that trigger apoptosis in cultured hepatocytes.	2002-02	11812934
Novel 4,1-benzoxazepine derivatives with potent squalene synthase inhibitory activities.	2002-02	11741788
Design and synthesis of motilin antagonists derived from the [1-4] fragment of porcine motilin.	2002-01-31	11806718
Rate acceleration of the Baylis-Hillman reaction in polar solvents (water and formamide). Dominant role of hydrogen bonding, not hydrophobic effects, is implicated.	2002-01-25	11798324
Generation, reactions, and kinetics of sterically congested triplet diphenylcarbenes. Effects of bromine groups.	2002-01-23	11792219
Tryparedoxin peroxidase of Leishmania donovani: molecular cloning, heterologous expression, specificity, and catalytic mechanism.	2002-01-15	11795890
Ipso-substitution by cytochrome P450 with conversion of p-hydroxybenzene derivatives to hydroquinone: evidence for hydroperoxo-iron as the active oxygen species.	2002-01-01	11747318
Formation of triacylglycerol core aldehydes during rapid oxidation of corn and sunflower oils with tert-butyl hydroperoxide/Fe2+.	2002-01	11876266
Odorants of different chemical classes interact with distinct odorant binding protein subtypes.	2002-01	11751466
Bis(oxazoline)copper complexes covalently bonded to insoluble support as catalysts in cyclopropanation reactions.	2001-12-28	11749620
Electronic structure of high-spin iron(III)-alkylperoxo complexes and its relation to low-spin analogues: reaction coordinate of O-O bond homolysis.	2001-12-26	11749538
Enantioselective hydrogenations of arylalkenes mediated by [Ir(cod) (JM-Phos) ]+ complexes.	2001-12-17	11822439
Efficient scavenging of hydroxyl radicals and inhibition of lipid peroxidation by novel analogues of 1,3,7-trimethyluric acid.	2001-12-14	11798008
Alkynylcyclohexanol chairs and twist-boats: Co(2)(CO)(6) as a conformational switch.	2001-12-14	11735541
Isolation of some glycosides as aroma precursors in young leaves of Japanese pepper (Xanthoxylum piperitum DC.).	2001-12	11743780
Acid-catalyzed isomerization of pivalaldehyde to methyl isopropyl ketone via a reactive protosolvated carboxonium ion intermediate.	2001-11-28	11716708
Synthesis and structure determination of kahalalide F (1,2).	2001-11-21	11707116
[Use of cyclodextrins in the formulation of polyalkylcyanoacrylate nanoparticles charged with different active ingredients].	2001-11	11924510
Synthesis and in vitro Trichomonacidal activities of some new dialkylperoxides and 1,2,4-trioxanes.	2001-10	11738490
Structure-activity relationship studies of (+/-)-terbutaline and (+/-)-fenoterol on beta3-adrenoceptors in the guinea pig gastric fundus.	2001-08	11885748
Sedanolide, a natural phthalide from celery seed oil: effect on hydrogen peroxide and tert-butyl hydroperoxide-induced toxicity in HepG2 and CaCo-2 human cell lines.	2001	11846995
Receptorphin: a conserved peptide derived from the sequence of the opioid receptor, with opioid displacement activity and potent antiproliferative actions in tumor cells.	2001	11737867

Substance Class	Chemical Created by `admin` on `Mon Mar 31 17:36:24 GMT 2025` Edited by `admin` on `Mon Mar 31 17:36:24 GMT 2025`
Record UNII	BXR49TP611
Record Status	`Validated (UNII)`
Record Version

Download

Name

Type

Language

R 600A

Preferred Name

English

ISOBUTANE

Official Name

English

ISOBUTANE [FCC]

Common Name

English

ISOBUTANE [VANDF]

Common Name

English

Isobutane [WHO-DD]

Common Name

English

ISOBUTANE [II]

Common Name

English

TRIMETHYLMETHANE

Systematic Name

English

ISOBUTANE [MART.]

Common Name

English

ISOBUTANE [HSDB]

Common Name

English

1,1-DIMETHYLETHANE

Systematic Name

English

Classification Tree Code System Code

NCI_THESAURUS

C552