Details
| Stereochemistry | ACHIRAL |
| Molecular Formula | C18H17FN4O |
| Molecular Weight | 324.3522 |
| Optical Activity | NONE |
| Defined Stereocenters | 0 / 0 |
| E/Z Centers | 0 |
| Charge | 0 |
SHOW SMILES / InChI
SMILES
CC(C)N1C=C(C=CC1=O)C2=NC=C(N)N=C2C3=CC=C(F)C=C3
InChI
InChIKey=MNUJNGGYFNZUNB-UHFFFAOYSA-N
InChI=1S/C18H17FN4O/c1-11(2)23-10-13(5-8-16(23)24)17-18(22-15(20)9-21-17)12-3-6-14(19)7-4-12/h3-11H,1-2H3,(H2,20,22)
| Molecular Formula | C18H17FN4O |
| Molecular Weight | 324.3522 |
| Charge | 0 |
| Count |
|
| Stereochemistry | ACHIRAL |
| Additional Stereochemistry | No |
| Defined Stereocenters | 0 / 0 |
| E/Z Centers | 0 |
| Optical Activity | NONE |
Approval Year
PubMed
| Title | Date | PubMed |
|---|---|---|
| A novel adenosine A(1) and A(2A) receptor antagonist ASP5854 ameliorates motor impairment in MPTP-treated marmosets: comparison with existing anti-Parkinson's disease drugs. | 2008-12-12 |
|
| Brain adenosine A2A receptor occupancy by a novel A1/A2A receptor antagonist, ASP5854, in rhesus monkeys: relationship to anticataleptic effect. | 2008-07 |
|
| Pharmacological characterization of a novel, potent adenosine A1 and A2A receptor dual antagonist, 5-[5-amino-3-(4-fluorophenyl)pyrazin-2-yl]-1-isopropylpyridine-2(1H)-one (ASP5854), in models of Parkinson's disease and cognition. | 2007-11 |
Patents
| Substance Class |
Chemical
Created
by
admin
on
Edited
Mon Mar 31 23:00:42 GMT 2025
by
admin
on
Mon Mar 31 23:00:42 GMT 2025
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| Record UNII |
BJS8Y4IC5V
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| Record Status |
Validated (UNII)
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| Record Version |
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Preferred Name | English | ||
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Common Name | English | ||
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| Code System | Code | Type | Description | ||
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851087-60-0
Created by
admin on Mon Mar 31 23:00:42 GMT 2025 , Edited by admin on Mon Mar 31 23:00:42 GMT 2025
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24810000
Created by
admin on Mon Mar 31 23:00:42 GMT 2025 , Edited by admin on Mon Mar 31 23:00:42 GMT 2025
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BJS8Y4IC5V
Created by
admin on Mon Mar 31 23:00:42 GMT 2025 , Edited by admin on Mon Mar 31 23:00:42 GMT 2025
|
PRIMARY |
| Related Record | Type | Details | ||
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ACTIVE MOIETY |
