ALLOMETHADIONE

Possibly Marketed Outside US

Details

Stereochemistry	RACEMIC
Molecular Formula	C7H9NO3
Molecular Weight	155.1513
Optical Activity	( + / - )
Defined Stereocenters	0 / 1
E/Z Centers	0
Charge	0

SHOW SMILES / InChI

Structure Search

SMILES

CC1OC(=O)N(CC=C)C1=O

InChI

InChIKey=XWZXRENCCHMZNF-UHFFFAOYSA-N

InChI=1S/C7H9NO3/c1-3-4-8-6(9)5(2)11-7(8)10/h3,5H,1,4H2,2H3

HIDE SMILES / InChI

Molecular Formula	C7H9NO3
Molecular Weight	155.1513
Charge	0
Count

Stereochemistry	RACEMIC
Additional Stereochemistry	No
Defined Stereocenters	0 / 1
E/Z Centers	0
Optical Activity	( + / - )

Description
Sources: https://www.ncbi.nlm.nih.gov/pubmed/14394344 | https://www.ncbi.nlm.nih.gov/pubmed/14908612 | https://www.ncbi.nlm.nih.gov/pubmed/13045529 | Vida, J. (2013) Anticonvulsants, page 186, retrieved from: https://books.google.ru/books?id=u-qOecoMmqMC

Allomethadione is an anticonvulsant. It was used for the treatment of epilepsy. Allomethadione appears to have the advantage over tridione (another anticonvulsant) in not producing ataxia or gastric irritation. Photophobia is common in patients taking tridione but allomethadione did not produce photophobia. The drug causes renal damage. The compound has been marketed in Europe.

Approval Year

Sample Use Guides

In Vivo Use Guide

0.3 g five times a day

Route of Administration: Oral

Substance Class	Chemical Created by `admin` on `Fri Dec 15 16:10:36 UTC 2023` Edited by `admin` on `Fri Dec 15 16:10:36 UTC 2023`
Record UNII	BFT641Z2YT
Record Status	`Validated (UNII)`
Record Version

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Name

Type

Language

ALLOMETHADIONE

Official Name

English

MALIDONE

Brand Name

English

allomethadione [INN]

Common Name

English

MALAZOL

Brand Name

English

2,4-OXAZOLIDINEDIONE, 5-METHYL-3-(2-PROPEN-1-YL)-

Systematic Name

English

ALOXIDONE [MI]

Common Name

English

3-ALLYL-5-METHYLOXAZOLIDINE-2,4-DIONE

Systematic Name

English

ALOXIDONE

Common Name

English

Classification Tree Code System Code

NCI_THESAURUS

C264