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Details

Stereochemistry ABSOLUTE
Molecular Formula C71H110N28O13
Molecular Weight 1563.8129
Optical Activity UNSPECIFIED
Defined Stereocenters 11 / 11
E/Z Centers 0
Charge 0

SHOW SMILES / InChI
Structure of ALA-LYS-ARG-HIS-HIS-GLY-TYR-LYS-ARG-LYS-PHE-HIS-NH2

SMILES

C[C@H](N)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CC1=CNC=N1)C(=O)N[C@@H](CC2=CNC=N2)C(=O)NCC(=O)N[C@@H](CC3=CC=C(O)C=C3)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CC4=CC=CC=C4)C(=O)N[C@@H](CC5=CNC=N5)C(N)=O

InChI

InChIKey=UIBPZXXSPHGPDS-GUBPWTFESA-N
InChI=1S/C71H110N28O13/c1-41(75)60(103)91-48(15-5-8-24-72)62(105)94-52(19-12-28-85-71(79)80)66(109)99-57(33-46-36-83-40-89-46)69(112)98-56(32-45-35-82-39-88-45)61(104)86-37-58(101)90-54(30-43-20-22-47(100)23-21-43)67(110)95-49(16-6-9-25-73)63(106)93-51(18-11-27-84-70(77)78)64(107)92-50(17-7-10-26-74)65(108)97-55(29-42-13-3-2-4-14-42)68(111)96-53(59(76)102)31-44-34-81-38-87-44/h2-4,13-14,20-23,34-36,38-41,48-57,100H,5-12,15-19,24-33,37,72-75H2,1H3,(H2,76,102)(H,81,87)(H,82,88)(H,83,89)(H,86,104)(H,90,101)(H,91,103)(H,92,107)(H,93,106)(H,94,105)(H,95,110)(H,96,111)(H,97,108)(H,98,112)(H,99,109)(H4,77,78,84)(H4,79,80,85)/t41-,48-,49-,50-,51-,52-,53-,54-,55-,56-,57-/m0/s1

HIDE SMILES / InChI

Molecular Formula C71H110N28O13
Molecular Weight 1563.8129
Charge 0
Count
Stereochemistry ABSOLUTE
Additional Stereochemistry No
Defined Stereocenters 11 / 11
E/Z Centers 7
Optical Activity UNSPECIFIED

Approval Year

PubMed

PubMed

TitleDatePubMed
Intracellular angiotensin II activates rat myometrium.
2011-09
Paraquat increases connective tissue growth factor and collagen expression via angiotensin signaling pathway in human lung fibroblasts.
2010-04
Effect of valsartan on angiotensin II-induced plasminogen activator inhibitor-1 biosynthesis in arterial smooth muscle cells.
2001-03
Role of central ANG II receptors in stress-induced cardiovascular and hyperthermic responses in rats.
1997-01
Angiotensin II antagonists.
1993-11
Characterization of alterations of hemodynamics and neuroendocrine hormones in dexamethasone induced hypertension in dogs.
1991
Identification of angiotensin II receptor subtypes.
1989-11-30
[Etiological studies of secondary hypertension. e. Drug-induced hypertension].
1984-02
Role of the anteroventral third ventricle region and the renin angiotensin system in methylprednisolone hypertension.
1981-11-01
Etiopathogenesis of excess methylprednisolone arterial hypertension in the rat.
1981
Rebound hypertensive after sodium nitroprusside prevented by saralasin in rats.
1980-02
Dopamine and saralasin antagonism of renal vasoconstriction and oliguria caused by amphotericin B in dogs.
1979-10
Effect of Sar1-ala8-angiotensin II on blood pressure and renin in Bartter's syndrome, before and after treatment with prostaglandin synthetase inhibitors.
1979-10
Substance Class Chemical
Created
by admin
on Mon Mar 31 18:07:24 GMT 2025
Edited
by admin
on Mon Mar 31 18:07:24 GMT 2025
Record UNII
B6WQB8NCPA
Record Status Validated (UNII)
Record Version
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Name Type Language
ALA-LYS-ARG-HIS-HIS-GLY-TYR-LYS-ARG-LYS-PHE-HIS-NH2
Common Name English
L-HISTIDINAMIDE, L-ALANYL-L-LYSYL-L-ARGINYL-L-HISTIDYL-L-HISTIDYLGLYCYL-L-TYROSYL-L-LYSYL-L-ARGINYL-L-LYSYL-L-PHENYLALANYL-
Preferred Name English
Code System Code Type Description
FDA UNII
B6WQB8NCPA
Created by admin on Mon Mar 31 18:07:24 GMT 2025 , Edited by admin on Mon Mar 31 18:07:24 GMT 2025
PRIMARY
PUBCHEM
16138585
Created by admin on Mon Mar 31 18:07:24 GMT 2025 , Edited by admin on Mon Mar 31 18:07:24 GMT 2025
PRIMARY
CAS
190673-58-6
Created by admin on Mon Mar 31 18:07:24 GMT 2025 , Edited by admin on Mon Mar 31 18:07:24 GMT 2025
PRIMARY
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