Details
| Stereochemistry | ACHIRAL |
| Molecular Formula | C13H11N3O5S |
| Molecular Weight | 321.309 |
| Optical Activity | NONE |
| Defined Stereocenters | 0 / 0 |
| E/Z Centers | 1 |
| Charge | 0 |
SHOW SMILES / InChI
SMILES
NS(=O)(=O)C1=CC=C(C=C1)\N=N\C2=CC(C(O)=O)=C(O)C=C2
InChI
InChIKey=NBSRUZQXRUNPNY-FOCLMDBBSA-N
InChI=1S/C13H11N3O5S/c14-22(20,21)10-4-1-8(2-5-10)15-16-9-3-6-12(17)11(7-9)13(18)19/h1-7,17H,(H,18,19)(H2,14,20,21)/b16-15+
| Molecular Formula | C13H11N3O5S |
| Molecular Weight | 321.309 |
| Charge | 0 |
| Count |
|
| Stereochemistry | ACHIRAL |
| Additional Stereochemistry | No |
| Defined Stereocenters | 0 / 0 |
| E/Z Centers | 1 |
| Optical Activity | NONE |
Salazosulfamide was studied for the treatment of ankylosing spondylitis. It was found that salazosulfamide efficacy is associated with N-acetyltransferase 1 polymorphisms and in particularly, NAT1 AA/GG genotype at 263 locus. However, future studies should be conducted to investigate these issues.
Approval Year
PubMed
| Title | Date | PubMed |
|---|---|---|
| Enhancement of reductive metabolism of p-nitrobenzoate and nitrazepam in isolated perfused rat liver by ethanol. | 1979 May-Jun |
|
| [Observation on therapeutic effect of heat needle combined with herb iontophoresis and western medicine on rheumatoid arthritis]. | 2007 Oct |
|
| NAT2 polymorphisms combining with smoking associated with breast cancer susceptibility: a meta-analysis. | 2010 Oct |
|
| Efficacy research of salazosulfamide in ankylosing spondylitis and NAT1 gene polymorphism. | 2017 Oct |
| Substance Class |
Chemical
Created
by
admin
on
Edited
Fri Dec 15 15:59:55 GMT 2023
by
admin
on
Fri Dec 15 15:59:55 GMT 2023
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| Record UNII |
B6831ORH7W
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| Record Status |
Validated (UNII)
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| Record Version |
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Official Name | English | ||
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Common Name | English | ||
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NCI_THESAURUS |
C29739
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100000080523
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C72640
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139-56-0
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CHEMBL377353
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205-366-7
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| Related Record | Type | Details | ||
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ACTIVE MOIETY |
