SALAZOSULFAMIDE

Details

Stereochemistry	ACHIRAL
Molecular Formula	C13H11N3O5S
Molecular Weight	321.309
Optical Activity	NONE
Defined Stereocenters	0 / 0
E/Z Centers	1
Charge	0

SHOW SMILES / InChI

Structure Search

SMILES

NS(=O)(=O)C1=CC=C(C=C1)\N=N\C2=CC(C(O)=O)=C(O)C=C2

InChI

InChIKey=NBSRUZQXRUNPNY-FOCLMDBBSA-N

InChI=1S/C13H11N3O5S/c14-22(20,21)10-4-1-8(2-5-10)15-16-9-3-6-12(17)11(7-9)13(18)19/h1-7,17H,(H,18,19)(H2,14,20,21)/b16-15+

HIDE SMILES / InChI

Molecular Formula	C13H11N3O5S
Molecular Weight	321.309
Charge	0
Count

Stereochemistry	ACHIRAL
Additional Stereochemistry	No
Defined Stereocenters	0 / 0
E/Z Centers	1
Optical Activity	NONE

Description
Sources: https://www.ncbi.nlm.nih.gov/pubmed/28912853

Salazosulfamide was studied for the treatment of ankylosing spondylitis. It was found that salazosulfamide efficacy is associated with N-acetyltransferase 1 polymorphisms and in particularly, NAT1 AA/GG genotype at 263 locus. However, future studies should be conducted to investigate these issues.

Approval Year

PubMed

Title	Date	PubMed
Efficacy research of salazosulfamide in ankylosing spondylitis and NAT1 gene polymorphism.	2017 Oct	28912853

Sample Use Guides

In Vivo Use Guide

The experimental group received 7.5 mg of salazosulfamide (MTX) per week

Route of Administration: Oral

Substance Class	Chemical Created by `admin` on `Fri Dec 15 15:59:55 GMT 2023` Edited by `admin` on `Fri Dec 15 15:59:55 GMT 2023`
Record UNII	B6831ORH7W
Record Status	`Validated (UNII)`
Record Version

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Name

Type

Language

SALAZOSULFAMIDE

Official Name

English

salazosulfamide [INN]

Common Name

English

NSC-27236

Code

English

Classification Tree Code System Code

NCI_THESAURUS

C29739