A-68930

NC[C@@H]1O[C@@H](CC2=C(O)C(O)=CC=C12)C3=CC=CC=C3

InChIKey=SUHGRZPINGKYNV-GJZGRUSLSA-N

InChI=1S/C16H17NO3/c17-9-15-11-6-7-13(18)16(19)12(11)8-14(20-15)10-4-2-1-3-5-10/h1-7,14-15,18-19H,8-9,17H2/t14-,15-/m0/s1

Stereochemistry	ABSOLUTE
Additional Stereochemistry	No
Defined Stereocenters	2 / 2
E/Z Centers	0
Optical Activity	UNSPECIFIED

Targets

Primary Target	Pharmacology	Condition	Potency
Dopamine D1 receptor 101 Target ID: CHEMBL2056 Sources: https://www.ncbi.nlm.nih.gov/pubmed/2143387	Agonist 2678		2.75 nM [EC50]
Dopamine D1 receptor 101 Target ID: CHEMBL2056 Sources: https://www.ncbi.nlm.nih.gov/pubmed/27067657\| https://www.ncbi.nlm.nih.gov/pubmed/26966979	Agonist 2678

PubMed

Title	Date	PubMed
Topographical assessment and pharmacological characterization of orofacial movements in mice: dopamine D(1)-like vs. D(2)-like receptor regulation.	2001 Apr 20	11334864
A 68930 and dihydrexidine inhibit locomotor activity and d-amphetamine-induced hyperactivity in rats: a role of inhibitory dopamine D(1/5) receptors in the prefrontal cortex?	2004	14960337
Differences between A 68930 and SKF 82958 could suggest synergistic roles of D1 and D5 receptors.	2005 Nov	16318870
Differential activation of adenylate cyclase and receptor internalization by novel dopamine D1 receptor agonists.	2005 Oct	15985612

Patents

Substance Class	Chemical Created by `admin` on `Fri Dec 15 18:00:32 GMT 2023` Edited by `admin` on `Fri Dec 15 18:00:32 GMT 2023`
Record UNII	B4NI77O5D4
Record Status	`Validated (UNII)`
Record Version

Name

Type

Language

A-68930

Common Name

English

A-70360

Code

English

1H-2-BENZOPYRAN-5,6-DIOL, 1-(AMINOMETHYL)-3,4-DIHYDRO-3-PHENYL-, (1R,3S)-

Systematic Name

English

A-70108

Code

English

Code System Code Type Description

WIKIPEDIA

A-68930