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Details

Stereochemistry ABSOLUTE
Molecular Formula C5H10O5
Molecular Weight 150.1299
Optical Activity UNSPECIFIED
Defined Stereocenters 3 / 3
E/Z Centers 0
Charge 0

SHOW SMILES / InChI
Structure of ARABINOSE, L-

SMILES

OC[C@H](O)[C@H](O)[C@@H](O)C=O

InChI

InChIKey=PYMYPHUHKUWMLA-VAYJURFESA-N
InChI=1S/C5H10O5/c6-1-3(8)5(10)4(9)2-7/h1,3-5,7-10H,2H2/t3-,4-,5+/m0/s1

HIDE SMILES / InChI

Molecular Formula C5H10O5
Molecular Weight 150.1299
Charge 0
Count
MOL RATIO 1 MOL RATIO (average)
Stereochemistry ABSOLUTE
Additional Stereochemistry No
Defined Stereocenters 3 / 3
E/Z Centers 0
Optical Activity UNSPECIFIED

Description

L-Arabinose is a monosaccharide extracted from plant gums, corn fiber and beet pulps. It is a poorly-absorbed, readily-available sweet-tasting pentose. L-Arabinose is known to suppress obesity by regulating the fasting blood glucose level and the insulin resistance index. L-arabinose is a non-caloric sugar. L-arabinose may inhibit intestinal sucrase activity and thereby delay sucrose digestion.

CNS Activity

Approval Year

Targets

Primary TargetPharmacologyConditionPotency
2.8 mM [Ki]

Conditions

ConditionModalityTargetsHighest PhaseProduct
Preventing
Unknown
Preventing
Unknown

Overview

CYP3A4CYP2C9CYP2D6hERG

OverviewOther

Other InhibitorOther SubstrateOther Inducer




Drug as perpetrator​

Sample Use Guides

In Vivo Use Guide
1,000 mg of l-arabinose and 200 ug of a patented food source chromium once daily.
Route of Administration: Oral
In Vitro Use Guide
Caco-2 cells were cultured for 21 d, homogenized, and used as an enzyme preparation with sucrose as substrate in concentrations from 7 to 280 mmol/L with 0.84, 1.4, and 2.8 mmol L-arabinose/L as inhibitor. The addition of L-arabinose resulted in uncompetitive inhibition of sucrase activity on 25%, 29%, and 38%, respectively.
Substance Class Chemical
Record UNII
B40ROO395Z
Record Status Validated (UNII)
Record Version