AKLOMIDE

Details

Stereochemistry	ACHIRAL
Molecular Formula	C7H5ClN2O3
Molecular Weight	200.579
Optical Activity	NONE
Defined Stereocenters	0 / 0
E/Z Centers	0
Charge	0

SHOW SMILES / InChI

Structure Search

SMILES

NC(=O)C1=C(Cl)C=C(C=C1)[N+]([O-])=O

InChI

InChIKey=GFGSZUNNBQXGMK-UHFFFAOYSA-N

InChI=1S/C7H5ClN2O3/c8-6-3-4(10(12)13)1-2-5(6)7(9)11/h1-3H,(H2,9,11)

HIDE SMILES / InChI

Molecular Formula	C7H5ClN2O3
Molecular Weight	200.579
Charge	0
Count

Stereochemistry	ACHIRAL
Additional Stereochemistry	No
Defined Stereocenters	0 / 0
E/Z Centers	0
Optical Activity	NONE

Description
Sources: https://www.gpo.gov/fdsys/pkg/CFR-2005-title21-vol6/pdf/CFR-2005-title21-vol6-sec558-35.pdf

Aklomide is an anticoccidial drug, which was approved by FDA fr the prevention of coccidiosis in chickens (in combination with sulfanitran), but lately withdrawn by the manufacturer decision.

Approval Year

Conditions

Condition	Modality	Targets	Highest Phase	Product
Coccidiosis 45 Sources: http://bionames.org/bionames-archive/issn/0018-0130/46/265.pdf	Preventing		Approved 8583	NOVASTAT Approved Use As an aid in the prevention of coccidiosis caused by E. tenella, E. necatrix, and E. acervulina.

PubMed

Title	Date	PubMed
Liquid chromatographic-electrochemical detection screening procedure for six nitro-containing drugs in chicken tissues at low ppb level.	1989-07-01	2759987
Simultaneous liquid chromatographic screening of five coccidiostats in chicken liver.	1988-01-01	3360706
Eimeria tenella: anticoccidial action of drugs in birds with surgically closed ceca.	1979-08	494707
Efficacy and cross-resistance studies on N, N'-bis (3,4 ditrifluoromethylphenyl) methylmalonamide, a novel anticoccidial agent.	1979-02	419002
Development of immunity to coccidiosis in chickens administered anticoccidials in feed.	1978-07-01	697660
beta-Glucuronidase activity in the urine, serum, kidney and bladder of rats fed 2-chloro-4-nitrobenzamide, 3,5-dinitrobenzamide or 3,5-dinitro-o-toluamide.	1969-07	5823977
The efficacy of 2-chloro-4-nitrobenzamide for the prevention and control of coccidiosis in chickens.	1966-03	5921881
The development of resistance to glycarbylamide and 2-chloro-4-nitrobenzamide in Eimeria tenella in chicks.	1966-02	5912231

Patents

Sample Use Guides

In Vivo Use Guide

Aklomide, 227 grams (0.025 percent) is combined with sulfanitran, 181.6 grams (0.02 percent) per ton of feed and given orally.

Route of Administration: Oral

In Vitro Use Guide

Unknown

Substance Class	Chemical Created by `admin` on `Mon Mar 31 17:54:30 GMT 2025` Edited by `admin` on `Mon Mar 31 17:54:30 GMT 2025`
Record UNII	B0E341RA20
Record Status	`Validated (UNII)`
Record Version

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Name

Type

Language

AKLOMIDE

Official Name

English

NSC-191832

Preferred Name

English

AKLOMIDE [MART.]

Common Name

English

BENZAMIDE, 2-CHLORO-4-NITRO-

Systematic Name

English

AKLOMIDE [GREEN BOOK]

Common Name

English

AKLOMIDE [MI]

Common Name

English

AKLOMIDE [USAN]

Common Name

English

2-Chloro-4-nitrobenzamide

Systematic Name

English

aklomide [INN]

Common Name

English

Classification Tree Code System Code

NCI_THESAURUS

C277