U.S. Department of Health & Human Services Divider Arrow National Institutes of Health Divider Arrow NCATS

Approval Year

Substance Class Protein
Created
by admin
on Sat Dec 16 15:26:02 GMT 2023
Edited
by admin
on Sat Dec 16 15:26:02 GMT 2023
Protein Type REGULATOR PROTEIN
Protein Sub Type
Sequence Origin HUMAN
Sequence Type COMPLETE
Record UNII
AYN2H2T5GU
Record Status Validated (UNII)
Record Version
  • Download
Name Type Language
Lusacomfar Alfa
INN  
Official Name English
H FACTOR 1
Common Name English
CFH
Common Name English
GEM103
Code English
Complement factor H (recombinant human clone 0213)
Common Name English
human complement factor H (CFH, H factor 1), produced in human embryonic kidney cells (HEK293), glycoform alfa
Common Name English
COMPLEMENT FACTOR H
Common Name English
lusacomfar alfa [INN]
Common Name English
GEM-103
Code English
Classification Tree Code System Code
FDA ORPHAN DRUG 260308
Created by admin on Sat Dec 16 15:26:02 GMT 2023 , Edited by admin on Sat Dec 16 15:26:02 GMT 2023
Code System Code Type Description
NCI_THESAURUS
C190421
Created by admin on Sat Dec 16 15:26:02 GMT 2023 , Edited by admin on Sat Dec 16 15:26:02 GMT 2023
PRIMARY
CAS
80295-65-4
Created by admin on Sat Dec 16 15:26:02 GMT 2023 , Edited by admin on Sat Dec 16 15:26:02 GMT 2023
NO STRUCTURE GIVEN
CAS
2640087-71-2
Created by admin on Sat Dec 16 15:26:02 GMT 2023 , Edited by admin on Sat Dec 16 15:26:02 GMT 2023
PRIMARY
UNIPROT
P08603
Created by admin on Sat Dec 16 15:26:02 GMT 2023 , Edited by admin on Sat Dec 16 15:26:02 GMT 2023
PRIMARY
FDA UNII
AYN2H2T5GU
Created by admin on Sat Dec 16 15:26:02 GMT 2023 , Edited by admin on Sat Dec 16 15:26:02 GMT 2023
PRIMARY
INN
12202
Created by admin on Sat Dec 16 15:26:02 GMT 2023 , Edited by admin on Sat Dec 16 15:26:02 GMT 2023
PRIMARY
From To
1_3 1_48
1_34 1_62
1_67 1_111
1_96 1_123
1_128 1_174
1_160 1_187
1_192 1_233
1_219 1_244
1_249 1_291
1_276 1_302
1_307 1_356
1_339 1_367
1_371 1_413
1_398 1_424
1_430 1_476
1_459 1_487
1_491 1_535
1_518 1_546
1_551 1_593
1_579 1_605
1_612 1_655
1_641 1_666
1_673 1_715
1_701 1_726
1_735 1_774
1_763 1_785
1_821 1_846
1_852 1_897
1_883 1_908
1_913 1_955
1_941 1_966
1_971 1_1014
1_1000 1_1025
1_1030 1_1073
1_1059 1_1084
1_1091 1_1134
1_1120 1_1145
1_1149 1_1200
1_1183 1_1210
1_793 1_835
Glycosylation Type HUMAN
Glycosylation Link Type Site
N 1_511
N 1_700
N 1_784
N 1_804
N 1_864
N 1_893
N 1_1011
N 1_1077
Related Record Type Details
LIGAND->TARGET
PRECLINICAL
Related Record Type Details
ACTIVE MOIETY
For the treatment of dry age-related macular degeneration (AMD).
Name Property Type Amount Referenced Substance Defining Parameters References
Molecular Formula CHEMICAL
MOL_WEIGHT CHEMICAL